Adenoviral vector-mediated gene delivery to injured rat peripheral nerve

Journal of Neurotrauma

Volumn 15, Issue 6, 1998, Pages 387-397

  Dijkhuizen, Paul A ^a   Pasterkamp, R Jeroen ^a   Hermens, Wim T J M C ^a   De Winter, Fred ^a   Giger, Roman J ^a   Verhaagen, Joost ^a,b  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

Adenoviral vector; Crush lesion; Degeneration; Regeneration; Schwann cell; Sciatic nerve

Indexed keywords

CELL ADHESION MOLECULE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRUSH TRAUMA; GENE TARGETING; GENE TRANSFER; NERVE DEGENERATION; NERVE FIBER GROWTH; NONHUMAN; PERIPHERAL NERVE INJURY; RAT; REPORTER GENE; SCHWANN CELL; SCIATIC NERVE; SIGNAL TRANSDUCTION; TRANSGENE;

EID: 0031799466     PISSN: 08977151     EISSN: None     Source Type: Journal    
DOI: 10.1089/neu.1998.15.387     Document Type: Article

References (60)

1. AIGNER, L., ARBER, S., KAPFHAMMER, J.P., et al. (1995). Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell 83, 269-278.
2. AKLI, S., CAILLAUD, C., VIGNE, E., STRATFORD-PERRICAUDET, L.D., PERRIDCAUDET M., and PESCHANSKI, M.R. (1993). Transfer of a foreign gene into the brain using adenovirus vectors. Nat. Genet. 3, 224-228.
3. BAJOCCHI, G., FELDMAN, S.H., CRYSTAL, R.G., and MASTRANGELI, A. (1993). Direct in vivo gene transfer to ependymal cells in the central nervous system using recombinant adenovirus vectors. Nat. Genet. 3, 229-234.
4. BIXBY, J.L., LILIEN, J., and REICHARDT, L.F. (1988). Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro. J. Cell Biol. 107, 353-361.
5. BIXBY, J.L., and ZHANG, R. (1990). Purified N-cadherin is a potent substrate for the rapid induction of neurite out-growth. J. Cell Biol. 110, 1253-1260.
6. CARLSTEDT, T.P., HALLIN, R.G., HEDSTRÖM, K.G., and NILSSON-REMAHL, I.A. (1993). Functional recovery in primates with brachial plexus injury after spinal cord implantation of avulsed ventral roots. J. Neurol. Neurosurg. Psychiatry 56, 649-654.
7. CARLSTEDT, T.P., GRANE, P., HALLIN, R.G., and NOREN, G. (1995). Return of function after spinal cord implantation of avulsed spinal nerve roots. Lancet 346, 1323-1325.
8. DAVIDSON, B.L., ALLEN, E.D., KOZARSKY, K.F., WILSON, J.M., and ROESSLER, R.J. (1993). A model system for in vivo gene transfer into the CNS using an adenoviral vector. Nat. Genet. 3, 219-223.
9. DE KONING, P., BRAKKEE, J.H., and GISPEN, W.H. (1986). Method for producing a reproducible crush in the sciatic and tibial nerve of the rat and rapid and precise testing of return of sensory function. Beneficial effects of melanocortins. J. Neurol. Sci. 74, 237-256.
10. DIJKHUIZEN, P.A., HERMENS, W.T.J.M.C., TEUNIS, M.A.T., and VERHAAGEN, J. (1997). Adenoviral vector-directed expression of neurotrophin-3 in rat dorsal root ganglion explants results in a robust neurite outgrowth response. J. Neurobiol. 33, 172-184.
11. EDSTRÖM, A., EKSTRÖM, P.A.R., and TONGE, D. (1993). Axonal outgrowth and neuronal apoptosis in cultured adult mouse dorsal root ganglion preparations: effects of neurotrophins, of inhibition of neurotrophin actions and of prior axotomy. Neuroscience 75, 1165-1174.
12. FALLAUX, F.J., KRANENBURG, O., CRAMER, S.J., et al. (1996). Characterization of 911: a new helper cell line for the titration and propagation of early-region-1-deleted adenoviral vectors. Hum. Gene Gher. 7, 215-222.
13. FINIELS, F., GIMENEZ Y RIBOTTA, M., BARKATS, M., et al. (1995). Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone diseases. Neuroreport 6, 2473-2478.
14. FRYKMAN, G.K. (1993). The quest for better recovery from peripheral nerve injury: current status of nerve regeneration research. J. Hand Ther. 6, 83-88.
15. FU, S.Y., and GORDON, T. (1997). The cellular and molecular basis of peripheral nerve regeneration. Mol. Neurobiol. 14, 67-116.
16. GAO, W.-Q., DYBDAL, N., SHINSKY, N., et al. (1995). Neurotrophin-3 reverses experimental cisplatin-induced peripheral sensory neuropathy. Ann. Neurol. 38, 30-37.
17. GESCHWIND, M.D., HARTNICK, C.J., LIU, W., AMAT, J., VAN DE WATER, T.R., and FEDEROFF, H.J. (1996). Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neunte outgrowth: model for treatment of neuron loss following cochlear degeneration. Human Gene Ther. 7, 173-182.
18. GHABRIEL, M.N., and ALLT, G. (1979). The role of Schmidt-Lanterman incisures in Wallerian degeneration. Acta Neuropathol. 48, 83-93.
19. GIGER, R.J., ZIEGLER, U., HERMENS, W.T.J.M.C., KUNZ, B., KUNZ, S., and SONDEREGGER, P. (1997). Adenovirus-mediated gene transfer in neurons: construction and characterization of a vector for heterologous expression of the axonal cell adhesion molecule axonin-1. J. Neurosci. Meth. 71, 99-111.
20. GLAZNER, G.W., LUPIEN, S., MILLER, J.A., and ISHII, D.N. (1993). Insulin-like growth factor II increases the rate of sciatic nerve regeneration in rats. Neuroscience 54, 791-797.
21. GRAHAM, F.L., and PREVEC, L. (1991). Manipulation of adenovirus vectors, in: Methods in Molecular Biology, Vol. 7, Gene Transfer and Expression Protocols. E.J. Murray, (Ed.), Humana Press: Clifton, NJ, pps. 109-129.
22. HASSANKHANI, A., STEINHELPER, M.E., SOONPAA, M.H., et al. (1995). Overexpression of NGF within the heart of transgenic mice causes hyperinnervation, cardiac enlargement and hyperplasia of ectopic cells. Dev. Biol. 169, 309-321.
23. HELGREN, M.E., CLIFFER, K.D., TORRENTO, K., et al. (1997). Neurotrophin-3 administration attenuates deficits of pyridoxine-induced large-fiber sensory neuropathy. J. Neurosci. 17, 372-382.
24. HERMENS, W.T.J.M.C., GIGER, R.J., HOLTMAAT, A.J.G.D., DIJKHUIZEN, P.A., HOUWELING, D.A., and VERHAAGEN, J. (1997). Transient gene transfer to neurons and glia: analysis of adenoviral vector performance in the CNS and PNS. J. Neurosci. Meth. 71, 85-98.
25. HERMENS, W.T.J.M.C., and VERHAAGEN, J. (1997). Adenoviral vector-mediated gene expression in the nervous system of immunocompetent wistar and T cell-deficient nude rats: preferential survival of transduced astroglial cells in nude rats. Hum. Gene Ther. 8, 1049-1063.
26. HOLTMAAT, A.J.G.D., DIJKHUIZEN, P.A., OESTREICHER, A.B., et al. (1995). Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular growth. J. Neurosci. 15, 7953-7965.
27. HORY-LEE, F., RUSSEL, M., LINDSAY, R.M., and FRANK, E. (1993). Neurotrophin-3 supports the survival of developing muscle sensory neurons in culture. Proc. Natl. Acad. Sci. USA 90, 2613-2617.
28. KAPLITT, M.G., PFAUS, J.G., KLEOPOULOS, S.P., HANLON, B.A., RABKIN, S.D., and PFAFF, D.W. (1991). Expression of a functional foreign gene in adult mammalian brain following in vivo transfer via a herpes simplex type 1 defective viral vector. Mol. Cell. Neurosci. 2, 320-330.
29. KAY, M.A., GOLTERMAN, A.-X., MEUSE, L., et al. (1995). Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration. Nat. Genet. 11, 191-197.
30. KLINE, D.G., and HUDSON, A.R. (1995). Nerve Injuries: Operative Results for Major Nerve Injuries, Entrapments and Tumors. W.B. Saunders: Philadelphia.
31. LANDER, A.D. (1987). Molecules that make axons grow. Mol. Neurobiol. 1, 213-245.
32. LE GAL LA SALLE, G., ROBERT, J.J., BERRARD, S., et al. (1993). An adenovirus vector for gene transfer into neurons and glia in the brain. Science 259, 988-990.
33. LEWIN, G.R., RITTER, A.M., and MENDELL, L.M. (1993) Nerve growth factor-induced hyperalgesia in the neonatal and adult rat. J. Comp. Neurol. 13, 2136-2148.
34. LINDSAY, R.M. (1988). Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons. J. Neurosci. 8, 2394-2405.
35. LUNDBORG, G. (1998). Nerve Injury and Repair. Churchill Livingstone: New York.
36. MATA, M., ALESSI, D., and FINK, D.J. (1990). S100 is preferentially distributed in myelin-forming Schwann cells. J. Neurocytol. 19, 432-442.
37. MCLEAN, I.W., and NAKANE, P.W. (1977). Periodate-lysine-paraformaldehyde fixative: a new fixative for immuno electron microscopy. J. Histochem. Cytochem. 22, 1077-1083.
38. MILLESI, H. (1993). Forty-two years of peripheral nerve surgery. Microsurgery 14, 228-233.
39. MOHAJERI, H., BARTSCH, U., VAN DER PUTTEN, H., SANSIG, G., MUCKE, L., and SCHACHNER, M. (1996). Neurite outgrowth on non-permissive substrates in vitro is enhanced by ectopic expression of the neural adhesion molecule L1 by mouse astrocytes. Eur. J. Neurosci. 8, 1085-1097.
40. MUNSON, J.B., SHELTON, D.L., and MCMAHON, S.B. (1997). Adult mammalian sensory and motor neurons: roles of endogenous neurotrophins and rescue by exogenous neurotrophins after axotomy. J. Neurosci. 17, 470-476.
41. PEEL, A.L., ZOLOTUKHIN, S., SCHRIMSHER, G.W., MUZYCZKA, N., and REIER, P.J. (1997). Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters. Gene Ther. 4, 16-24.
42. RICH, K.M., ALEXANDER, T.D., PRYOR, J.C., and HOLLOWELL, J.P. (1989). Nerve growth factor enhances regeneration through silicone chambers. Exp. Neurol. 105, 162-170.
43. SAHENK, Z., SEHARASEYON, J., and MENDELL, J.R. (1994). CNTF potentiates peripheral nerve regeneration. Brain Res. 655, 246-250.
44. SAIDA, T., SAIDA, K., SILBERBERG, D.H., and BROWN, M.J. (1978). Transfer of demyelination by intraneural injection of experimental allergic neuritis serum. Nature 272, 639-641.
45. SAWCHUK, S.J., BOIVIN, G.P., DUWEL, L.E., et al. (1996). Anti-T cell receptor monoclonal antibody prolongs transgene expression following adenovirus-mediated in vivo gene transfer to mouse synovium. Hum. Gene Ther. 7, 499-506.
46. SECKEL, B.R. (1990). Enhancement of peripheral nerve regeneration. Muscle Nerve 13, 785-800.
47. SEILHEIMER, B., and SCHACHNER, M. (1988). Studies of adhesion molecules mediating interactions between cells of peripheral nervous systems indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture. J. Cell Biol. 107, 341-351.
48. SHY, M.E., TANI, M., SHI, Y.J., et al. (1995). An adenoviral vector can transfer LacZ expression into Schwann cells in culture and in sciatic nerve. Ann. Neurol. 38, 429-436.
49. SMITH, G.M., HALE, J., PASNIKOWSKI, E.M., LINDSAY, R.M., WONG, V., and RUDGE, J.S. (1996). Astrocytes infected with replication-defective adenovirus containing a secreted form of CNTF or NT-3 show enhanced support of neuronal populations in vitro. Exp. Neurol. 139, 156-166.
50. STERNE, G.D., BROWN, R.A., GREEN, C.J., and TERENGHI, G. (1997). Neurotrophin-3 delivered locally via fibronection mats enhances peripheral nerve regeneration. Eur. J. Neurosci. 9, 1388-1396.
51. SUNDERLAND, S. (1991). Nerve Injuries and Their Repair: A Critical Appraisal. Churchill Livingstone: Edinburgh.
52. USHIKI, T., and IDE, C. (1987). Scanning electron microscopic studies of the myelinated nerve fibres of the mouse sciatic nerve with special reference to the Schwann cell cytoplasmic network external to the myelin sheath. J. Neurocytol. 16, 737-747.
53. VAN LEEUWEN, F.W. (1988). An introduction to immunoelectron microscopy in neuroscience, in: Molecular Neuroanatomy (F.W. Van Leeuwen, R.M. Buijs, C.W. Pool, and O. Pach (eds). Elsevier Science Publishers: Amsterdam.
54. VERHAAGEN, J., EDWARDS, P.M., JENNEKENS, F.G.I., SCHOTMAN, P., and GISPEN, W.H. (1986). Characterization of epitopes shared by alpha-melanocyte-stimulating hormone and the 150 kD neurofilament protein (NF150): relationship to neurotrophic sequences. J. Neurosci. Res. 16, 589-600.
55. VERHAAGEN, J., EDWARDS, P.M., JENNEKENS, F.G.I., SCHOTMAN, P., and GISPEN, W.H. (1987). Early effect of an ACTH(4-9) analog (Org 2766) on regenerative sprouting demonstrated by the use of neurofilament-binding antibodies isolated from a serum raised by a-MSH immunization. Brain Res. 404, 142-150.
56. VOGT, L., GIGER, R.J., ZIEGLER, U., et al. (1996). Continuous renewal of the axonal pathway sensor apparatus by insertion of new sensor molecules into the growth cone membrane. Curr. Biol. 6, 1153-1158.
57. WATCHMAKER, G.P., and MACKINNON, S.E. (1997). Advances in peripheral nerve repair. Clin. Plast. Surg. 24, 63-73.
58. WILLIAMS, P.L., and HALL, S.M. (1971). Chronic Wallerian degeneration - an in vivo and ultrastructural study. J. Anat. 109, 487-503.
59. WINKLER, J., RAMIREZ, G.A., KUHN, H.G., et al. (1997). Reversible Schwann cell hyperplasia and sprouting of sensory and sympathetic neuntes after intraventricular administration of nerve growth factor. Ann. Neurol. 41, 82-93.
60. YANG, Y., SY, Q., GREWAL, I.S., SCHILZ, R., FLAVELL, R.A., and WILSON, J.M. (1996). Transient subversion of CD40 ligand function diminishes immune responses to adenovirus vectors in mouse liver and lung tissues. J. Virol. 70, 6370-6377.