A pilot study of fiberscopy-guided local injection of anti-cancer drugs bound to carbon particles for control of rectal cancer

Anti-Cancer Drugs

Volumn 9, Issue 4, 1998, Pages 363-367

  Hagiwara, Akeo ^a   Hirata, Youichi ^b   Takahashi, Toshio ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b Inoshita Hospital   (Japan)

Author keywords

Activated carbon particles; Ameliorative therapy; Anti cancer drugs; Rectal cancer

Indexed keywords

ACTIVATED CARBON; ANTINEOPLASTIC AGENT; METHOTREXATE; MITOMYCIN C; POVIDONE; POVIDONE K30; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER SIZE; CASE REPORT; CLINICAL TRIAL; COLONOSCOPY; DRUG DOSAGE FORM; DRUG FORMULATION; FEMALE; FEVER; FIBEROSCOPE; HUMAN; INJECTION; MALE; PRIORITY JOURNAL; RECTUM CARCINOMA;

EID: 0031799239     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199804000-00011     Document Type: Article

References (4)

1. Ballard BE. Biopharmaceutical considerations in subcutaneous and intramuscular drug administration. J Pharm Sci 1968; 57: 357-78.
2. Rusznyak I, Foldi M, Szabo G. Absorption into lymph capillaries. In: Youlten L, ed. Lymphatics and lymph circulation, physiology and pathology, 2nd edn. London: Pergamon 1967: 418-74.
3. Hagiwara A, Takahashi T, Sawai K, et al. Selective delivery of a greater amount of methotrexate to regional lymph nodes using a new dosage formulation, methotrexate adsorbed on activated carbon particles, in mice. Anti-Cancer Drugs 1994; 5: 194-8.
4. Hagiwara A, Takahashi T, Sawai K, et al. Lymph nodal vital staining with newer carbon particle suspensions compared with india ink. Lymphology 1992; 25: 84-9.