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Volumn 16, Issue 6, 1998, Pages 2025-2031

bcl-2 automated and quantitative immunocytochemical assays in breast carcinomas: Correlation with 10-year follow-up

Author keywords

[No Author keywords available]

Indexed keywords

PEROXIDASE; PROTEIN BCL 2;

EID: 0031799122     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/JCO.1998.16.6.2025     Document Type: Article
Times cited : (53)

References (45)
  • 1
    • 0023491915 scopus 로고
    • Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
    • Wyllie AH, Morris RG, Smith AL, et al: Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis. J Pathol 153:313-319, 1987
    • (1987) J Pathol , vol.153 , pp. 313-319
    • Wyllie, A.H.1    Morris, R.G.2    Smith, A.L.3
  • 2
    • 0027479796 scopus 로고
    • Apoptosis (The 1992 Frank Rose Memorial Lecture)
    • Wyllie AH: Apoptosis (The 1992 Frank Rose Memorial Lecture). Br J Cancer 67:205-208, 1993
    • (1993) Br J Cancer , vol.67 , pp. 205-208
    • Wyllie, A.H.1
  • 3
    • 0025204548 scopus 로고
    • bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, et al: bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:34-37, 1990
    • (1990) Nature , vol.348 , pp. 34-37
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3
  • 4
    • 0028040019 scopus 로고
    • bcl-2 and the regulation of programmed cell death
    • Reed JC: bcl-2 and the regulation of programmed cell death. J Cell Biol 124:1-6, 1994
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 5
    • 0029328602 scopus 로고
    • bcl-2, a novel regulator of cell death
    • Hockenbery DM: bcl-2, a novel regulator of cell death. BioEssays 17:631-638, 1995
    • (1995) BioEssays , vol.17 , pp. 631-638
    • Hockenbery, D.M.1
  • 6
    • 0030596710 scopus 로고    scopus 로고
    • Apoptosis provides new targets for chemotherapy
    • Holzman D: Apoptosis provides new targets for chemotherapy. J Natl Cancer Inst 88:1098-1100, 1996
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1098-1100
    • Holzman, D.1
  • 7
    • 0024988359 scopus 로고
    • Activation of programmed cell death by anticancer agents: Cisplatin as a model system
    • Eastman A: Activation of programmed cell death by anticancer agents: Cisplatin as a model system. Cancer Cells 2:275-280, 1990
    • (1990) Cancer Cells , vol.2 , pp. 275-280
    • Eastman, A.1
  • 8
    • 0026781986 scopus 로고
    • bcl-2 gene transfer increases relative resistance of S49.1 and WEH17.2 lymphoid cells to cell death and DNA fragmentation induced by glycocorticoids and multiple chemotherapeutic drugs
    • Miyashita T, Reed JC: bcl-2 gene transfer increases relative resistance of S49.1 and WEH17.2 lymphoid cells to cell death and DNA fragmentation induced by glycocorticoids and multiple chemotherapeutic drugs. Cancer Res 52:5407-5411, 1992
    • (1992) Cancer Res , vol.52 , pp. 5407-5411
    • Miyashita, T.1    Reed, J.C.2
  • 9
    • 0027389763 scopus 로고
    • bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC: bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 81:151-157, 1993
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 10
    • 0026599125 scopus 로고
    • Involvement of bcl-2 in glucocorticoid-induced apoptosis of human pre-B leukemia
    • Alnemri ES, Fernandez TF, Haldar S, et al: Involvement of bcl-2 in glucocorticoid-induced apoptosis of human pre-B leukemia. Cancer Res 52:491-495, 1992
    • (1992) Cancer Res , vol.52 , pp. 491-495
    • Alnemri, E.S.1    Fernandez, T.F.2    Haldar, S.3
  • 11
    • 0027279128 scopus 로고
    • bcl-2 modulation of apoptosis induced by anticancer drugs: Resistance to thymidylate stress is independent of classical resistance pathways
    • Fisher TC, Milner AE, Gregory CD, et al: bcl-2 modulation of apoptosis induced by anticancer drugs: Resistance to thymidylate stress is independent of classical resistance pathways. Cancer Res 53:3321-3327, 1993
    • (1993) Cancer Res , vol.53 , pp. 3321-3327
    • Fisher, T.C.1    Milner, A.E.2    Gregory, C.D.3
  • 12
    • 0023786047 scopus 로고
    • bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux D, Cory S, Adams J: bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440-442, 1988
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.1    Cory, S.2    Adams, J.3
  • 13
    • 0028214472 scopus 로고
    • The bcl-2 protein: A prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients
    • Silvestrini R, Veneroni S, Daidone MG, et al: The bcl-2 protein: A prognostic indicator strongly related to p53 protein in lymph node-negative breast cancer patients. J Natl Cancer Inst 86:499-504, 1994
    • (1994) J Natl Cancer Inst , vol.86 , pp. 499-504
    • Silvestrini, R.1    Veneroni, S.2    Daidone, M.G.3
  • 14
    • 0029077154 scopus 로고
    • Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis
    • Lipponen P, Pietillaïnen T, Kosma VM, et al: Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis. J Pathol 177:49-55, 1995
    • (1995) J Pathol , vol.177 , pp. 49-55
    • Lipponen, P.1    Pietillaïnen, T.2    Kosma, V.M.3
  • 15
    • 0029117078 scopus 로고
    • Prognostic value of bcl-2 expression in invasive breast cancer
    • Hellemans P, Van Dam PA, Weyler J, et al: Prognostic value of bcl-2 expression in invasive breast cancer. Br J Cancer 72:354-360, 1995
    • (1995) Br J Cancer , vol.72 , pp. 354-360
    • Hellemans, P.1    Van Dam, P.A.2    Weyler, J.3
  • 16
    • 0029863353 scopus 로고    scopus 로고
    • p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients
    • Silvestrini R, Benini E, Veneroni S, et al: p53 and bcl-2 expression correlates with clinical outcome in a series of node-positive breast cancer patients. J Clin Oncol 14:1604-1610, 1996
    • (1996) J Clin Oncol , vol.14 , pp. 1604-1610
    • Silvestrini, R.1    Benini, E.2    Veneroni, S.3
  • 17
    • 0027945796 scopus 로고
    • Modulation of bcl-2 and Ki-67 expression in oestrogen receptor-positive human breast cancer by tamoxifen
    • Johnston SRD, MacLennan KA, Sacks NPM, et al: Modulation of bcl-2 and Ki-67 expression in oestrogen receptor-positive human breast cancer by tamoxifen. Eur J Cancer 30A: 1662-1669, 1994
    • (1994) Eur J Cancer , vol.30 A , pp. 1662-1669
    • Johnston, S.R.D.1    MacLennan, K.A.2    Sacks, N.P.M.3
  • 18
    • 0027970798 scopus 로고
    • Immunocytochemical localization of bcl-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy
    • Gee JMW, Robertson JFR, Ellis IO, et al: Immunocytochemical localization of bcl-2 protein in human breast cancers and its relationship to a series of prognostic markers and response to endocrine therapy. Int J Cancer 59:619-628, 1994
    • (1994) Int J Cancer , vol.59 , pp. 619-628
    • Gee, J.M.W.1    Robertson, J.F.R.2    Ellis, I.O.3
  • 19
    • 0029157380 scopus 로고
    • Estrogen promotes chemotherapeutic drug resistance by a mechanism involving bcl-2 proto-oncogene expression in human breast cancer cells
    • Teixeira C, Reed JC, Pratt MAC: Estrogen promotes chemotherapeutic drug resistance by a mechanism involving bcl-2 proto-oncogene expression in human breast cancer cells. Cancer Res 55:3902-3907, 1995
    • (1995) Cancer Res , vol.55 , pp. 3902-3907
    • Teixeira, C.1    Reed, J.C.2    Pratt, M.A.C.3
  • 20
    • 0028247257 scopus 로고
    • Expression of bcl-2 in primary breast cancer and its correlation with tumour phenotype
    • Nathan B, Gusterson B, Jadayel D, et al: Expression of bcl-2 in primary breast cancer and its correlation with tumour phenotype. Ann Oncol 5:409-414, 1994
    • (1994) Ann Oncol , vol.5 , pp. 409-414
    • Nathan, B.1    Gusterson, B.2    Jadayel, D.3
  • 21
    • 84871471435 scopus 로고    scopus 로고
    • Automated and quantitative immunocytochemical assays of bcl-2 protein in breast carcinomas
    • in press
    • Charpin C, Garcia S, Bouvier C, et al: Automated and quantitative immunocytochemical assays of bcl-2 protein in breast carcinomas. Br J Cancer (in press)
    • Br J Cancer
    • Charpin, C.1    Garcia, S.2    Bouvier, C.3
  • 22
    • 0028173370 scopus 로고
    • Quantitative immunocytochemical assays of P-glycoprotein in breast carcinomas: Correlation to messenger RNA expression and to immunohistochemical prognostic indicators
    • Charpin C, Vielh P, Duffaud F, et al: Quantitative immunocytochemical assays of P-glycoprotein in breast carcinomas: Correlation to messenger RNA expression and to immunohistochemical prognostic indicators. J Natl Cancer Inst 86:1539-1545, 1994
    • (1994) J Natl Cancer Inst , vol.86 , pp. 1539-1545
    • Charpin, C.1    Vielh, P.2    Duffaud, F.3
  • 23
    • 0028948280 scopus 로고
    • CD 31 quantitative immunohistochemical assays in breast carcinomas. Correlation with current prognostic factors
    • Charpin C, Devictor B, Bergeret D, et al: CD 31 quantitative immunohistochemical assays in breast carcinomas. Correlation with current prognostic factors. Am J Clin Path 103:443-448, 1995
    • (1995) Am J Clin Path , vol.103 , pp. 443-448
    • Charpin, C.1    Devictor, B.2    Bergeret, D.3
  • 24
    • 0026808390 scopus 로고
    • The Nottingham prognostic index in primary breast cancer
    • Galea MH, Blarney RW, Elston CE, et al: The Nottingham prognostic index in primary breast cancer. Br Cancer Res Treat 22:207-219, 1992
    • (1992) Br Cancer Res Treat , vol.22 , pp. 207-219
    • Galea, M.H.1    Blarney, R.W.2    Elston, C.E.3
  • 25
    • 0022546957 scopus 로고
    • Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
    • Tsujimoto Y, Croce CM: Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci 83:5214-5218, 1986
    • (1986) Proc Natl Acad Sci , vol.83 , pp. 5214-5218
    • Tsujimoto, Y.1    Croce, C.M.2
  • 26
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t (14:18) translocation
    • Clearly ML, Smith SD, Sklar J: Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t (14:18) translocation. Cell 47:19-28, 1986
    • (1986) Cell , vol.47 , pp. 19-28
    • Clearly, M.L.1    Smith, S.D.2    Sklar, J.3
  • 28
    • 0029119560 scopus 로고
    • CDC25 phosphatases as potential human oncogenes
    • Galaktionov K, Lee AK, Eckstein J, et al: CDC25 phosphatases as potential human oncogenes. Science 269:1575-1577, 1995
    • (1995) Science , vol.269 , pp. 1575-1577
    • Galaktionov, K.1    Lee, A.K.2    Eckstein, J.3
  • 29
    • 0028799275 scopus 로고
    • Characterization of monoclonal antibodies against stromelysin-3 and their use to evaluate stromelysin-3 levels in breast carcinoma by semi-quantitative immunohistochemistry
    • Santavicca M, Noel A, Chenard MP, et al: Characterization of monoclonal antibodies against stromelysin-3 and their use to evaluate stromelysin-3 levels in breast carcinoma by semi-quantitative immunohistochemistry. Int J Cancer 64:336-341, 1995
    • (1995) Int J Cancer , vol.64 , pp. 336-341
    • Santavicca, M.1    Noel, A.2    Chenard, M.P.3
  • 30
    • 84965819899 scopus 로고
    • Multiparametric evaluation (SAMBA) of growth fraction (monoclonal Ki67) in breast carcinoma: A correlation of immunodetection in tissues sections and morphological data and estrogen and progesterone receptor immunocytochemical assays
    • Charpin C, Andrac L, Vacheret H, et al: Multiparametric evaluation (SAMBA) of growth fraction (monoclonal Ki67) in breast carcinoma: A correlation of immunodetection in tissues sections and morphological data and estrogen and progesterone receptor immunocytochemical assays. Cancer Res 48:4368-4374, 1988
    • (1988) Cancer Res , vol.48 , pp. 4368-4374
    • Charpin, C.1    Andrac, L.2    Vacheret, H.3
  • 31
    • 0028000255 scopus 로고
    • Biologic significance of quantitative estrogen receptor immunohistochemical assay by image analysis in breast cancer
    • Esteban JM, Cul AHN, Mehta P, et al: Biologic significance of quantitative estrogen receptor immunohistochemical assay by image analysis in breast cancer. Am J Clin Pathol 102:158-162, 1994
    • (1994) Am J Clin Pathol , vol.102 , pp. 158-162
    • Esteban, J.M.1    Cul, A.H.N.2    Mehta, P.3
  • 32
    • 0028106525 scopus 로고
    • Image analysis of in situ cell cycle related changes of PCNA and Ki-67 proliferation antigen expression
    • Santisteban MS, Brugal G: Image analysis of in situ cell cycle related changes of PCNA and Ki-67 proliferation antigen expression. Cell Prolif 27:435-453, 1994
    • (1994) Cell Prolif , vol.27 , pp. 435-453
    • Santisteban, M.S.1    Brugal, G.2
  • 33
    • 0028179558 scopus 로고
    • Dangers of using "optimal" cutpoint in the evaluation of prognostic factors
    • Altman DG, Lausen B, Sauerberi W, et al: Dangers of using "optimal" cutpoint in the evaluation of prognostic factors. J Natl Cancer Inst 86:829-835, 1994
    • (1994) J Natl Cancer Inst , vol.86 , pp. 829-835
    • Altman, D.G.1    Lausen, B.2    Sauerberi, W.3
  • 34
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto Y, Cossman J, Jaffe E, et al: Involvement of the bcl-2 gene in human follicular lymphoma. Science 228:1440-1443, 1985
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3
  • 35
    • 0026655474 scopus 로고
    • bcl-2 initiates a new category of oncogenes regulators of cell death
    • Korsmeyer SJ: bcl-2 initiates a new category of oncogenes regulators of cell death. Blood 80:879-886, 1992
    • (1992) Blood , vol.80 , pp. 879-886
    • Korsmeyer, S.J.1
  • 36
    • 0026664430 scopus 로고
    • Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice
    • Siegel RM, Katsumata M, Miyashita T, et al: Inhibition of thymocyte apoptosis and negative antigenic selection in bcl-2 transgenic mice. Proc Natl Acad Sci 89:7003-7007, 1992
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 7003-7007
    • Siegel, R.M.1    Katsumata, M.2    Miyashita, T.3
  • 37
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
    • Krajewski S, Tanaka S, Takayama S, et al: Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 53:4701-4714, 1993
    • (1993) Cancer Res , vol.53 , pp. 4701-4714
    • Krajewski, S.1    Tanaka, S.2    Takayama, S.3
  • 38
    • 0030140057 scopus 로고    scopus 로고
    • Regulation of apoptosis by bcl-2 and its related proteins: Immunochemical challenges and therapeutic implications
    • Kernohan NM, Cox LS: Regulation of apoptosis by bcl-2 and its related proteins: Immunochemical challenges and therapeutic implications. J Pathol 179:1-3, 1996
    • (1996) J Pathol , vol.179 , pp. 1-3
    • Kernohan, N.M.1    Cox, L.S.2
  • 39
    • 0029815350 scopus 로고    scopus 로고
    • bcl-2 proto-oncogene, apoptosis and oncogenesis: An overview
    • Kandouz M, Compel A, Therwath A: bcl-2 proto-oncogene, apoptosis and oncogenesis: An overview. Int J Oncol 9:563-566, 1996
    • (1996) Int J Oncol , vol.9 , pp. 563-566
    • Kandouz, M.1    Compel, A.2    Therwath, A.3
  • 40
    • 0027166048 scopus 로고
    • bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer SJ: bcl-2 heterodimerizes in vivo with a conserved homolog, bax, that accelerates programmed cell death. Cell 74:609-619, 1993
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 41
    • 0028809209 scopus 로고
    • Bad, a heterodimeric partner for bcl-xL and bcl-2 displaces ax and promotes cell death
    • Yang E, Zha J, Jock l J, et al: bad, a heterodimeric partner for bcl-xL and bcl-2 displaces ax and promotes cell death. Cell 80:285-921, 1995
    • (1995) Cell , vol.80 , pp. 285-921
    • Yang, E.1    Zha, J.2    Jock, L.J.3
  • 42
    • 0028986876 scopus 로고
    • Induction of apoptosis by the bcl-2 homologue bak
    • Chittenden T, Harrington EA, O'Connor R, et al: Induction of apoptosis by the bcl-2 homologue bak. Nature 374:733-736, 1995
    • (1995) Nature , vol.374 , pp. 733-736
    • Chittenden, T.1    Harrington, E.A.2    O'Connor, R.3
  • 43
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel bcl-2 binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, et al: Cloning and functional analysis of BAG-1: A novel bcl-2 binding protein with anti-cell death activity. Cell 80:279-284, 1995
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3
  • 44
    • 0028290446 scopus 로고
    • Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2
    • Gottschalk AR, Boise LH, Thompson CB, et al: Identification of immunosuppressant-induced apoptosis in a murine B-cell line and its prevention by bcl-x but not bcl-2. Proc Natl Acad Sci 91:7350-7354, 1994
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 7350-7354
    • Gottschalk, A.R.1    Boise, L.H.2    Thompson, C.B.3
  • 45
    • 0028335717 scopus 로고
    • Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo
    • Miyashita T, Krajewski S, Krajewska M, et al: Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo. Oncogene 9:1799-1805, 1994
    • (1994) Oncogene , vol.9 , pp. 1799-1805
    • Miyashita, T.1    Krajewski, S.2    Krajewska, M.3


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