Dose-response curve and time-course of effect of vecuronium in male and female patients

British Journal of Anaesthesia

Volumn 80, Issue 6, 1998, Pages 720-724

  Xue, F S ^a   Liao, X ^a   Liu, J H ^a   Tong, S Y ^a   Zhang, Y M ^a   Zhang, R J ^a   An, G ^a   Luo, L K ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Gender; Neuromuscular block vecuronium; Pharmacodynamics vecuronium

Indexed keywords

FENTANYL; NITROUS OXIDE; THIOPENTAL; VECURONIUM;

ADULT; ARTICLE; CLINICAL TRIAL; DOSE TIME EFFECT RELATION; ELECTIVE SURGERY; FEMALE; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; MUSCLE EXCITATION; MYOGRAPHY; NEUROMUSCULAR FUNCTION; NORMAL HUMAN; PLASTIC SURGERY; PRIORITY JOURNAL; SEX DIFFERENCE; WRIST;

EID: 0031798736     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/80.6.720     Document Type: Article

References (26)

1. Elliott MP, Mirakhur RK, Cooper R, Sharpe TDE, Clarke RSJ. Onset and duration of action of vecuronium in the elderly: comparison with adults. Acta Anaesthesiologica Scandinavica 1992; 36: 383-386.
2. D'Hollander A, Massaux F, Nevelsteen M, Agoston S. Age-dependent dose-response relationship of ORG NC 45 in anaesthetized patients. British Journal of Anaesthesia 1982; 54: 653-657.
3. Lebrault C, Berger JL, D'Hollander AA, Gemeni R, Henzel D, Duvaldestin P. Pharmacokinetics and pharmacodynamics of vecuronium (Org NC45) in patients with cirrhosis. Anesthesiology 1985; 62: 601-605.
4. Funk DI, Crul JF, van der Pol FM. Effect of changes in acid-base balance on neuromuscular blockade produced by ORG NC 45. Acta Anaesthesiologica Scandinavica 1980; 24: 119-124.
5. Buzello W, Schluermann D, Schindler M, Spillner G. Hypothermic cardiopulmonary bypass and vecuronium blockade by pancuronium and vecuronium. Anesthesiology 1985; 62: 201-204.
6. Schwartz AE, Matto RS, Ornstein E, Halevy JD, Diaz J. Pharmacokinetics and pharmacodynamics of vecuronium in the obese surgical patients. Anesthesia and Analgesia 1992; 74: 515-518.
7. Mcindewar IC, Marshall RJ. Interaction between the neuromuscular blocking drug ORG NC 45 and some anaesthetics, analgesics and antimicrobial agents. British Journal of Anaesthesia 1981; 53: 785-791.
8. Rupp SM, Miller RD, Gencarelli J. Vecuronium-induced neuromuscular blockade during enflurane, isoflurane, and halo thane anesthesia in human. Anesthesiology 1984; 41: 102-105.
9. Morita T, Tsukagoshi H, Sugaya T, Yoshikawa D, Fujita T. The effects of sevoflurane are similar to those of isoflurane on the neuromuscular block produced by vecuronium. British Journal of Anaesthesia 1994; 72: 465-476.
10. Pandit SK, Ferres CJ, Gibson FM, Mirakhur RK. Time- course of action of combinations of vecuronium and pancuronium. Anaesthesia 1986; 41: 151-154.
11. Krieg N, Hendrickx HHL, Crul JF. Influence of suxamethonium on the potency of ORG NC 45 in anaesthetized patients. British Journal of Anaesthesia 1981; 53: 259-262.
12. Buzzello W, Noeldge G, Krieg N, Brobmann GF. Vecuronium for muscle relaxation in patients with myasthenia gravis. Anesthesiology 1986; 64: 507-509.
13. Semple P, Hope DA, Clyburn P, Rodbert A. Relative potency of vecuronium in male and female patients in Britain and Australia. British Journal of Anaesthesia 1994; 72: 190-194.
14. Houghton IT, Aun CST, Oh TE. Vecuronium: an anthropometrie comparison. Anaesthesia 1992; 47: 741-746.
15. Gramstad L, Lilleasen P. Neuromuscular effects of atracuronium, vecuronium and pancuronium during bolus and infusion administration. British Journal of Anaesthesia 1985; 57: 1052-1059.
16. Donlon JV. A new approach to the study of four nondepolarizing relaxants in man. Anesthesia and Analgesia 1974; 53: 934-939.
17. Waud BE, Waud DR. On dose-response curves and anesthetics. Anesthesiology 1970; 33: 1-4.
18. Gibson FM, Mirakhur RK, Clarke RSJ, Lavery GG. Comparison of cumulative and single bolus dose techniques for determining the potency of vecuronium. British Journal of Anaesthesia 1985; 57: 1060-1062.
19. Smith CE, Donati F, Bevan DR. Cumulative dose-response with infusion: A technique to determine neuromuscular blocking potency of atracurium and vecuronium. Clinical Pharmacology and Therapeutics 1988; 44: 56-64.
20. Fisher DM, Fahey MR, Cronnelly R, Miller RD. Potency determination for vecuronium (Org NC 45): Comparison of cumulative and single-dose techniques. Anesthesiology 1982; 57: 309-312.
21. Vanlinthout LEH, Booij LHO, Egmond JV, Robertson EN. Effect of isoflurane and sevoflurane on the magnitude and time-course of neuromuscular block produced by vecuronium, pancuronium and atracurium. British Journal of Anaesthesia 1996; 76: 389-395.
22. Krieg N, Crul TF, Booij LHD. Relative potency of ORG NC 45, Pancuronium, alcuronium and tubocurarine in anaesthetized man. British Journal of Anaesthesia 1980; 52: 783-787.
23. Friis-Hansen B. Body composition during growth. In vivo measurements and biochemical data correlated to differential anatomical growth. Paediatrics 1971; 47: 264-274.
24. Meretoja OA. Neuromuscular blocking agents in paediatric patients: influence of age on the response. Anaesthesia and Intensive Care 1990; 18: 440-448.
25. Giudcelli JF, Tillement JP. Influence of sex on drug kinetics in man. Clinical Pharmacokinetics 1977; 2: 157-166.
26. Duvaldestin P, Henzel D. Binding of tubocurarine, fazadinium, pancuronium and ORG NC 45 to serum protein in normal man and in patients with cirrhosis. British Journal of Anaesthesia 1982; 54: 513-516.