Ocular residence time of carboxymethylcellulose solutions

Advances in Experimental Medicine and Biology

Volumn 438, Issue , 1998, Pages 761-767

  Paugh, Jerry R ^a   Chatelier, Ronald C ^b   Huff, Joseph W ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b CSIRO   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AQUALON; BORIC ACID; BUFFER; CARBOXYMETHYLCELLULOSE; DRUG VEHICLE; EYE DROPS; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG FORMULATION; DRUG INSTILLATION; EYE; FLOW KINETICS; FLUOROMETRY; HUMAN; HUMAN EXPERIMENT; MEAN RESIDENCE TIME; MOLECULAR WEIGHT; NORMAL HUMAN; PLASTICITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SHEAR RATE; TOPICAL DRUG ADMINISTRATION; VISCOSITY;

EID: 0031797547     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5359-5_107     Document Type: Conference Paper

References (14)

1. Maurice DM, Srinivas SP. Use of fluorometry in assessing the efficacy of a cation-sensitive gel as an ophthalmic vehicle: Comparison with scintigraphy. J Pharm Sci. 1992;81:615-619.
2. Paugh JR, Meadows DL, Garcia CG, et al. Evaluating the ocular retention time of two different artificial tear polymers using fluorophotometry in patients with dry eye. ARVO Abstracts. Invest Ophthalmol Vis Sci. 1994;35:S1694.
3. Meadows DL, Joshi AJ, Paugh JR. Diagnostic apparatus for determining pre-corneal retention time of ophthalmic formulations. US Patent #5,323,775; 1994.
4. Bron AJ, Tiffany JM. Pseudoplastic materials as tear substitutes: An exercise in design. In: van Bijsterveld OP, Lemp MA, Spinelli D, eds. The Lacrimal System. Symposium on the Lacrimal System, Singapore, March 17, 1990. Amsterdam: Kugler & Ghedini; 1991;27-33.
5. Ludwig A, van Ooteghem M. The evaluation of viscous ophthalmic vehicles by slit lamp fluorophotometry in humans. Int J Pharm. 1989;54:95-102.
6. Bothner H, Wik O. Rheology of hyaluronate. Acta Otolaryngol Suppl. 1987;442:25-30.
7. Zaki I, Fitzgerald P, Hardy JG, Wilson CG. A comparison of the effect of viscosity on the precorneal residence of solutions in rabbit and man. J Pharm Pharmacol. 1986;38:463-466.
8. Smart JD, Kellaway IW, Worthington HEC. An in vitro investigation of mucosa-adhesive materials for use in controlled drug delivery. J Pharm Pharmacol. 1984;36:295-299.
9. Leung SS, Robinson JR. The contribution of anionic polymer structural features to mucoadhesion. J Cont Release. 1988;5:223-231.
10. Mortazavi SA, Smart JD. Factors influencing gel-strengthening at the mucoadhesive-mucous interface. J Pharm Pharmacol. 1994;46:86-90.
11. Ludwig A, Unl̈u N, van Ooteghem M. Evaluation of viscous ophthalmic vehicles containing carbomer by slit-lamp fluorophotometry in humans. Int J Pharm. 1990;61:15-25.
12. Snibson GR, Greaves JL, Soper ND, Prydal JL, Wilson CG, Bron AJ. Precorneal residence times of sodium hyaluronate solutions studied by quantitative gamma scintigraphy. Eye. 1990;4:594-602.
13. ASTM Standard D 2196. Standard test methods for rheological properties of non-Newtonian materials by rotational (Brookfield) viscometer. Annual Book of ASTM Standards. Philadelphia: ASTM; 1991.
14. Tiffany JM. The viscosity of human tears. Int Ophthalmol. 1991;15:371-376.