Sex differences in discriminative stimulus and diuretic effects of the κ opioid agonist U69,593 in the rat

Pharmacology Biochemistry and Behavior

Volumn 61, Issue 4, 1998, Pages 395-403

  Craft, Rebecca M ^a   Kruzich, Paul J ^a   Boyer, Jill S ^a   Harding, Joseph W ^a   Hanesworth, Jody M ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Discrimination; Diuresis; Opioids; Sex differences; U69,593

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 HYDROXYBENZYL] N,N DIETHYLBENZAMIDE; BREMAZOCINE; ETHYLKETAZOCINE; KAPPA OPIATE RECEPTOR AGONIST; MORPHINE; N METHYL N [7 (1 PYRROLIDINYL) 1 OXASPIRO[4.5]DEC 8 YL]BENZENEACETAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DIURESIS; DRUG DISCRIMINATION; DRUG EFFECT; FEMALE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEX DIFFERENCE; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031797262     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(98)00124-5     Document Type: Article

References (50)

1. Baamonde, A. I.; Hidalgo, A.; Andres-Trelles, F.: Sex-related differences in the effects of morphine and stress on visceral pain. Neuropharmacology 28:967-970; 1989.
2. Bartok, R. E.; Craft, R. M.: Sex differences in opioid antinociception. J. Pharmacol. Exp. Ther. 282:769-778; 1997.
3. Beatty, W. W.; Holzer, G. A.: Sex differences in stereotyped behavior in the rat. Pharmacol. Biochem. Behav. 9:777-783; 1978.
4. Becker, J. B.; Robinson, T. E.; Lorenz, K. A.: Sex differences and estrous cycle variations in amphetamine-elicited rotational behavior. Eur. J. Pharmacol. 80:65-72; 1982.
5. Camp, D. M.; Robinson, T. E.: Susceptibility to sensitization. I. Sex differences in the enduring effects of chronic D-amphetamine treatment on locomotion, stereotyped behavior and brain monoamines. Behav. Brain Res. 30:55-68; 1988.
6. Chait, L. D.; Uhlenhuth, E. H.; Johanson, C-E.: Individual differences in the discriminative stimulus effects of d-amphetamine in humans. Drug Dev. Res. 16:451-460; 1989.
7. Cicero, T.; Nock, B.; Meyer, E.: Gender-related differences in the antinociceptive properties of morphine. J. Pharmacol. Exp. Ther. 279:767-773; 1996.
8. Comer, S. D.; McNutt, R. W.; Chang, K.-J.; DeCosta, B. R.; Mosberg, H. I.; Woods, J. H.: Discriminative stimulus effects of BW373U86: A nonpeptide ligand with selectivity for delta opioid receptors. J. Pharmacol. Exp. Ther. 267:866-874; 1993.
9. Craft, R. M.; Heideman, L. M.; Bartok, R. E.: Effect of gonadectomy on discriminative stimulus effects of morphine in female vs. male rats. Drug Alcohol Depend, (in press).
10. Craft, R.M.; Stratmann, J.A.: Discriminative stimulus properties of cocaine in female versus male rats. Drug Alcohol Depend. 42:27-37; 1996.
11. Craft, R. M.; Kalivas, P.; Stratmann, J. A.: Sex differences in discriminative stimulus effects of morphine. Behav. Pharmacol. 7:764-778; 1996.
12. Crofton, J. T.; Baer, P. G.; Share, L.; Brooks, D. P.: Vasopressin release in male and female rats: Effects of gonadectomy and treatment with gonadal steroid hormones. Endocrinology 117:1195-1200; 1985.
13. DeVries, G. J.; Buijs, R. M.; VanLeeuwen, F. W.: Sex differences in vasopressin and other neurotransmitter systems in the brain. In: DeVries, G. J.; DeBruin, J. P. C.; Uylings, H. B. M.; Corner, M. A., eds. Sex differences in the brain (progress in brain research, vol. 61). Amsterdam: Elsevier; 1984:185-203.
14. Eisenberg, R. M.: The occurrence of cross-tolerance between morphine and ethyl-ketocyclazocine using the tail-flick test: Lack of effect of diazepam, phenobarbital, or amphetamine. Life Sci. 37:915-922; 1985.
15. Forgie, M. L.; Stewart, J.: Sex differences in the locomotor-activating effects of amphetamine: Role of circulating testosterone in adulthood. Physiol. Behav. 55:6390-644; 1994.
16. Freeman, M. E.: The ovarian cycle in the rat. In: Knobil, E.; Neill, J., eds. The physiology of reproduction. New York: Raven Press; 1988:1893-1928.
17. Gear, R.; Gordon, N.; Heller, P.; Paul, S.; Miaskowski, C.; Levine, J.: Gender difference in analgesic response to the kappa-opioid pentazocine. Neurosci. Lett. 205:207-209; 1996.
18. Gear, R.; Miaskowski, C.; Gordon, N.; Paul, S.; Heller, P.; Levine, J.: Kappa-opioids produce significantly greater analgesia in women than in men. Nat. Med. 2:1248-1250; 1996.
19. Hammer, R. P.: μ-Opiate receptor binding in the medial preoptic area is cyclical and sexually dimorphic. Brain Res. 515:187-192; 1990.
20. Holtzman, S. G.; Cook, L.; Steinfels, G. F.: Discriminative stimulus effects of spiradoline, a kappa-opioid agonist. Psychopharmacology (Belrin) 105:447-452; 1991.
21. Kavaliers, M.; Innes, D.: Sex and day-night differences in opiate-induced responses of insular wild deer mice, Peromyscus maniculatus triangularis. Pharmacol. Biochem. Behav. 27:477-482; 1987.
22. Kepler, K. L.; Kest, B.; Kiefel, J. M.; Cooper, M. L.; Bodnar, R. J.: Roles of gender, gonadectomy and estrous phase in the analgesic effects of intracerebroventricular morphine in rats. Pharmacol. Biochem. Behav. 34:119-127; 1989.
23. Kepler, K. L.; Standifer, K. M.; Paul, D.; Kest, B.; Pasternak, G. W.; Bodnar, R. J.: Gender effects and central opioid analgesia. Pain 45:87-94; 1991.
24. 3H]U-69593: A highly selective ligand for the opioid receptor. Eur. J. Pharmacol. 109:281-284; 1985.
25. Leander, J. D.: A kappa opioid effect: Increased urination in the rat. J. Pharmacol. Exp. Ther. 224:89-94; 1983.
26. Leander, J. D.: Further study of kappa opioids on increased urination. J. Pharmacol. Exp. Ther. 227:35-41; 1983.
27. Leander, J. D.; Hart, J. C.; Zerbe, R. L.: Kappa agonist-induced diuresis: Evidence for stereoselectivity, strain differences, independence of hydration variables and a result of decreased plasma vasopressin levels. J. Pharmacol. Exp. Ther. 242:33-39; 1987.
28. Leander, J. D.; Zerbe, R. L.; Hart, J. C.: Diuresis and suppression of vasopressin by kappa opioids: Comparison with mu and delta opioids and clonidine. J. Pharmacol. Exp. Ther. 234:463-469; 1985.
29. Locke, K. W.; Gorney, G.; Cornfeldt, M.; Fielding, S.: Mu-opioid component of the ethylketocyclazocine (EKC) discriminative stimulus in the rat. Psychopharmacology (Berlin) 99:492-496; 1989.
30. O'Neal, M. F.; Means, L. W.; Porter, J. H.; Rosecrans, J. A.; Mokler, D. J.: Rats that acquire a THC discrimination more rapidly are more sensitive to THC and faster in reaching operant criteria. Pharmacol. Biochem. Behav. 29:67-71; 1988.
31. Negus, S. S.; Morgan, D.; Cook, C. D.; Picker, M. J.: Effects of the delta opioid agonist BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure. Psychopharmacology (Berlin) 126:199-205; 1996.
32. Negus, S. S.; Picker, M. J.; Dykstra, L. A.: Interactions between mu and kappa opioid agonists in the rat drug discrimination procedure. Psychopharmacology (Berlin) 102:465-473; 1990.
33. Negus, S. S.; Picker, M. J.; Dykstra, L. A.: Interactions between the discriminative stimulus effects of mu and kappa opioid agonists in the squirrel monkey. J. Pharmacol. Exp. Ther. 256:149-158; 1991.
34. Perkins, K. A.; DiMarco, A.; Grobe, J. E.; Scierka, A.; Stiller, R. L.: Nicotine discrimination in male and female smokers. Psychopharmacology (Berlin) 116:407-413; 1994.
35. Picker, M. J.; Doty, P.; Negus, S. S.; Mattox, S. R.; Dykstra, L. A.: Discriminative stimulus properties of U50,488 and morphine: Effects of training dose on stimulus substitution patterns produced by mu and kappa opioid agonists. J. Pharmacol. Exp. Ther. 254:13-22; 1990.
36. Picker, M. J.; Dykstra, L. A.: Comparison of the discriminative stimulus properties of U50,488 and morphine in pigeons. J. Pharmacol. Exp. Ther. 243:938-945; 1987.
37. Picker, M. J.; Negus, S. S.; Powell, K. R.: Differential cross-tolerance to mu and kappa opioid agonists in morphine-tolerant rats responding under a schedule of food presentation. Psychopharmacology (Berlin) 103:129-135; 1991.
38. Porreca, F.; Cowan, A.; Raffa, R. B.; Tallarida, R. J.: Tolerance and cross-tolerance studies with morphine and ethylketazocine. J. Pharm. Pharmacol. 34:666-667; 1982.
39. Salas, S. P.; Roblero, J.; Ureta, H.; Huidobro-Toro, J. P.: Diuretic effect of bremazocine, a kappa-opioid with central and peripheral sites of action. J. Pharmacol. Exp. Ther. 250:992-999; 1989.
40. Schecter, M. D.: Drug sensitivity of individual rats determines degree of drug discrimination. Pharmacol. Biochem. Behav. 19:1-4; 1983.
41. Shearman, G. T.; Herz, A.: Discriminative stimulus properties of bremazocine in the rat. Neuropharmacology 20:1209-1213; 1981.
42. Shearman, G. T.; Herz, A.: Evidence that the discriminative stimulus properties of fentanyl and ethylketazocine are mediated by an interaction with different opiate receptors. J. Pharmacol. Exp. Ther. 221:735-739; 1982.
43. Simerly, R. B.; McCall, L. D.; Watson, S. J.: Distribution of opioid peptides in the preoptic region: Immunohistochemical evidence for a steroid-sensitive enkephalin sexual dimorphism. J. Comp. Neurol. 276:442-459; 1988.
44. Smith, M. A.; Picker, M. J.: Examination of the kappa agonist and antagonist properties of opioids in the rat drug discrimination procedure: Influence of training dose and intrinsic efficacy. Behav. Pharmacol. 6:703-717; 1995.
45. Solomon, R.; Wasserman, E.; Gebhardt, G.: Tolerance to antinociceptive effects of morphine without tolerance to its effects on schedule controlled behavior. Psychopharmacology (Berlin) 92:327-333; 1987.
46. Soulard, C. D.; Guerif, S.; Payne, A.; Dahl, S. G.: Differential effects of fedotozine compared to other agonists on diuresis in rats. J. Pharmacol. Exp. Ther. 279:1379-1385; 1996.
47. Tallarida, R. J.; Murray, R. B.: Manual of pharmacologic calculations with computer programs, version 4. Philadelphia: Microcomputer Specialists; 1987.
48. van Haaren, F.; Meyer, M. E.: Sex differences in locomotor activity after acute and chronic cocaine administration. Pharmacol. Biochem. Behav. 39:923-927; 1991.
49. Wang, Y.-X.; Edwards, R. M.; Nambi, P.; Stack, E. J.; Pullen, M.; Share, L.; Crofton, J. T.; Brooks, D. P.: Sex difference in the antidiuretic activity of vasopressin in the rat. Am. J. Physiol. 265:R1284-R1290; 1993.
50. Yamada, K.; Imai, M.; Yoshida, S.: Mechanism of diuretic action of U-62,066E, a K opioid receptor agonist. Eur. J. Pharmacol. 160:229-237; 1989.