A case of MELAS showing CSF pleocytosis associated with stroke-like episodes

Clinical Neurology

Volumn 38, Issue 7, 1998, Pages 641-644

  Maruyama, Shun Ichiro ^a   Yamada, Takeshi ^a   Ishimoto, Yuko ^a   Hara, Hideo ^a   Taniwaki, Takayuki ^a   Kira, Jun Ichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

CSF pleocytosis; MELAS; Mitochondria; Stroke like episodes

Indexed keywords

GADOLINIUM PENTETATE; UBIDECARENONE;

ADULT; APHASIA; ARTICLE; BICEPS BRACHII MUSCLE; BLOOD BRAIN BARRIER; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; FEMALE; HOMONYMOUS HEMIANOPIA; HUMAN; INFLAMMATION; MELAS SYNDROME; MUSCLE BIOPSY; PLEOCYTOSIS; PROTON NUCLEAR MAGNETIC RESONANCE; STROKE;

CEREBROVASCULAR DISORDERS; FEMALE; HUMANS; LEUKOCYTOSIS; MELAS SYNDROME; MIDDLE AGED;

EID: 0031797123     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Robeck S, Stefan H, Engelhardt A, et al : Verlaufsbeobachtungen und endokrinologische Funktionsstorungen beim MELAS-Syndrom. Nervenarzt 67 : 465-470, 1996
2. Graham SH, Meyerhoff DJ, Bayne L, et al : Magnetic resonance spectroscopy of N-acetyl-aspartate in hypoxicischemic encephalopathy. Ann Neurol 35 : 490-494, 1994
3. (I I R) gene associated with MELAS subgroup of mitochondrial encephalomyopathies. Nature 348 : 651-653, 1990
4. Goto Y, Nonaka I, Horai S : A new mtDNA mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). Biochim Biophys Acta 1097 : 238-240, 1991
5. (I I R) gene in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). Biochem Biophys Res Commun 202 : 1624-1630, 1994
6. Morten KJ, Cooper JM, Brown GK, et al : A new point mutation associated with mitochondrial encephalomyopathy. Hum Mol Genet 2 : 2081-2087, 1993
7. (I I R) gene. Q J Med 86 : 709-713, 1993
8. Manfredi G, Schon EA, Moraes CT, et al : A new mutation associated with MELAS is located in a mitochondrial DNA polypeptide-coding gene. Neuromusc Dis 5 : 391-398, 1995
9. Barry E, Hauser WA : Pleocytosis after status epilepticus. Arch Neurol 51 : 190-193, 1994
10. Ohama E, Ohara S, Ikuta F, et al : Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy. Acta Neuropathol 74 : 226-233, 1987
11. Sakuta R, Nonaka I : Vascular involvement in mitochondrial myopathy. Ann Neurol 25 : 594-601, 1989
12. Hasegawa H, Matsuoka T, Goto Y, et al : Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes. Ann Neurol 29 : 601-605, 1991
13. Harding AE, Sweeney MG, Miller DH, et al : Occurence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation. Brain 115 : 979-989, 1992