Effect of different combinations of hydroxypropylmethyl cellulose on bioavailability of ibuprofen from press-coated time-controlled tablets

S.T.P. Pharma Sciences

Volumn 8, Issue 3, 1998, Pages 155-161

  Halsas, M ^a   Simelius, R ^a   Kiviniemi, A ^a   Veski, P ^b   Jurjenson H ^b   Marvola, M ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF TARTU   (Estonia)

Author keywords

Bioavailability; Compression coating; HPMC; Ibuprofen; Tablets; Time controlled release

Indexed keywords

HYDROXYPROPYLMETHYLCELLULOSE; IBUPROFEN; METHYLCELLULOSE;

ARTICLE; BIOAVAILABILITY; CIRCADIAN RHYTHM; DRUG BLOOD LEVEL; DRUG COATING; DRUG DOSAGE FORM; DRUG EFFECT; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; SUSTAINED RELEASE PREPARATION;

EID: 0031796993     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. LEMMER B. - The clinical relevance of chronopharmacology in therapeutics. - Pharmacol. Res., 33, 107-115, 1996.
2. MARVOLA M. and SIRKIÄ T. - Controlled release pharmaceutical preparations, Finnish patent 93924, 1995.
3. WILSON C.G., WASHINGTON N., GREAVES I., KAMALI F., REES J., SEMPIK A. and LAMPARD J. - Bimodal release of ibuprofen in a sustained release formulation: a scintigraphic and pharmacokinetic open study in healthy volunteers under different conditions of food intake. - Int. J. Pharm., 50, 211-281, 1989.
4. RITSCHEL W.A. - Handbook of Basic Pharmacokinetics, 4th Ed., Hamilton Press, Illinois, 1992, p. 541.
5. SKEITH K. and BROCKS D. - Pharmacokinetic optimisation of the treatment of osteoarthritis. - Clin. Pharmacokinet., 26, 233-242, 1994.
6. LABRECQUE G., BUREAU J.P. and REINBERG A.E. - Biological rhythms in the inflammatory response and in the effects of non-steroidal anti-inflammatory drugs. - Pharm. Ther., 66, 285-300, 1995.
7. SHAH A.C., BRITTEN N.J., OLANOFF L.S. and BADALAMENTI J.N. - Gel-matrix systems exhibiting bimodal controlled release for oral drug delivery. - J. Controlled Release, 9, 169-175, 1989.
8. TAHARA K., YAMAMOTO K. and NISHIHATA T. - Overall mechanism behind matrix sustained release (SR) tablets prepared with hydroxypropylmethyl cellulose 2910. - J. Controlled Release, 35, 59-66, 1995.
9. ALDERMAN D.A. - Review of cellulose ethers in hydrophilic matrices for oral controlled-release dosage forms. - Int. J. Pharm. Tech. and Prod. Mfr., 5, 1-9, 1984.
10. HALSAS M., ERVASTI P., VESKI, P. JÖRJENSON H. and MARVOLA M. - Biopharmaceutical evaluation of time-controlled press-coated tablets containing polymers to adjust drug release. - Proceedings of the Sixth European Congress of Biopharmaceutics and Pharmacokinetics, Athens, 22-24 April 1996, in press.
11. AVGERINOS A. and HUTT A.J. - High-performance liquid chromatographic determination of ibuprofen in human plasma and urine by direct injection. - J. Chromatogr., 380, 468-471 1986.
12. SHAH V.P., MIDHA K.K., DIGHE S., MCGILVERAY I.J., SKELLY J.P., YACOBI A., LAYLOFF T., VISWANATHAN C.T., COOK C.E., McDOWALL R.D., PITTMAN K.A. and SPECTOR S. - Analytical methods validation: Bioavailability, bioequivalence, and pharmacokinetic studies. - J. Pharm. Sci., 81, 309-312 1992.
13. Methocel Cellulose Ethers, Technical Handbook. - The Dow Chemical Company, USA.
14. FORD J., RUBINSTEIN M. and HOGAN J. - Propranolol hydrochloride and aminophylline release from matrix tablets containing hydroxypropylmethyl cellulose. - Int. J. Pharm., 24, 339-350, 1985.
15. SIRKIÄ J., MÄKIMARTTI M., LIUKKO-SIPI S. and MARVOLA M. - Development and biopharmaceutical evaluations of a new press-coated prolonged-release salbutamol sulphate tablet in man - Eur. J. Pharm., 1, 195-201, 1994.
16. PARR A., BEIHN R., FRANZ R., SZPUNAR G. and JAY M. - Correlation of ibuprofen bioavailability with gastrointestinal transit by cintigraphic monitoring of 171Er-labeled sustained release tablets. - Pharm. Res., 4, 486-489, 1987.