Genotyping microsatellite polymorphisms by agarose gel electrophoresis with ethidium bromide staining: Application to quantitative trait loci analysis of seizure susceptibility in mice

Psychiatric Genetics

Volumn 8, Issue 4, 1998, Pages 227-233

  Ferraro, T N ^a   Schill, J F ^a   Ballas, C ^a   Mulholland, N ^a   Golden, G T ^a,b   Smith, G G ^a,b   Buono, R J ^a   Berrettini, W H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Agarose gel electrophoresis; Epilepsy; Genotyping; Microsatellites; Mouse; Quantitative trait locus mapping; Seizures

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ETHIDIUM BROMIDE; MICROSATELLITE DNA; PENTETRAZOLE; RECEPTOR SUBUNIT;

AGAR GEL ELECTROPHORESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHROMOSOME 5; CONTROLLED STUDY; DNA DETERMINATION; DNA POLYMORPHISM; GENE AMPLIFICATION; GENE LOCUS; GENE MAPPING; GENETIC SUSCEPTIBILITY; GENOTYPE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SEIZURE; SEIZURE SUSCEPTIBILITY;

ANIMALIA;

EID: 0031795244     PISSN: 09558829     EISSN: None     Source Type: Journal    
DOI: 10.1097/00041444-199808040-00005     Document Type: Article

References (26)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA et al. (1998). Current protocols in molecular biology, Volume 1. New York: Wiley-Interscience. pp. 255-259.
2. Berrettini WH, Ferraro TN, Alexander RA, Vogel H (1994). Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains. Nat Genet 7:54-58.
3. Brilliant MH, Williams RW, Holdener BC, Angel JM (1996). Encyclopedia of the mouse genome V. Mouse chromosome 7. Mamm Genome 6:S135-S150.
4. Crook R, Hardy J, Duff K (1994). Single-day apolipoprotein E genotyping. J Neurosci Meth 53:125-127.
5. Dietrich W, Kat H, Lincoln SE, Shin SE, Friedman J, Dracopoli N, Lander ES (1992). A genetic map suitable for typing intraspecific crosses. Genetics 131:423-447.
6. Dietrich WF, Miller J, Steen RG, Merchant M, Damron D, Nahf R et al. (1994). A genetic map of the mouse with 4,006 simple sequence length polymorphism. Nat Genet. 7:220-245.
7. Ferraro TN, Berrettini WH (1996). Quantitative trait loci mapping in mouse models of complex behavior. In: Function and dysfunction in the nervous system, proceedings of the cold spring harbor symposium on quantitative biology. New York: Cold Spring Harbor. pp. 771-781.
8. Ferraro TN, Golden GT, Smith GG, Schork NJ, St Jean P, Ballas C, Berrettini WH (1997). Mapping murine loci for seizure response to kainic acid. Mamm Genome 8:200-208.
9. Flaherty L (1981). Congenic strains. In: The mouse in biomedical research, Vol. 1. Foster HL, Small JD, Fox JG (editors). New York: Academic Press, pp. 215-222.
10. Kosobud AE, Crabbe JC (1990). Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs. Brain Res 526:8-16.
11. Kosobud AE, Crabbe JC (1992). Neural sensitivity to pentylenetetrazol convulsions in inbred and selectively bred mice. Brain Res 592:122-128.
12. Kline MC, Redman JW, Reeder DJ, Duewer DL (1996). Intercomparison of DNA sizing ladders in electrophoretic separation matrices and their potential for accurate typing of the D1S80 locus. Appl Theor Electrophor 6:33-41.
13. Kozak CA, Bucan M, Goffinet A, Stephenson DA (1996). Encyclopedia of the mouse genome V. Mouse chromosome 5. Mamm Genome 6:S97-S112.
14. Lahiri DK, Nurnberger JI (1991). A rapid non-enzymatic method for the preparation of high molecular weight DNA from blood for RFLP studies. Nucl Acid Res 19:5444.
15. Lander ES, Kruglyak L (1995). Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
16. MacDonald RL, Barker JL (1977). Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated postsynaptic inhibition in cultured mammalian neurones. Nature 267:720-721.
17. Mock BA, Stoye J, Spence J, Jackson I, Eppig JT, Fiedorek FT, Neumann PE (1996). Encyclopedia of the mouse genome V. Mouse chromosome 4. Mamm Genome 6:S73-S96.
18. Porter RJ, Cereghino JJ, Gladding GD, Hessie BJ, Kupferberg HJ, Scoville B, White BG (1984). Anitepileptic drug development program. Cleve Clin Quarterly 51:293-305.
19. Reymer PW, Groenemeyer BE, van de Burg R, Kastelein JJ (1995). Apolipoprotein E genotyping on agarose gels. Clin Chem 41:1046-1047.
20. Routman E, Cheverud J (1994). A rapid method of scoring simple sequence repeat polymorphisms with agarose gel electrophoresis. Mamm Genome 5:187-188.
21. Saiki RK, Gelfand H, Stoffel S, Scharf SJ, Higushi R, Horn GT et al. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science 239:487-491.
22. Sambrook J, Fritsch EF, Maniatis T (1989). Molecular cloning: a laboratory manual. New York: Cold Spring Harbor, pp. B.1-B.28.
23. Tanksley SD, McCouch SR (1997). Seed banks and molecular maps: unlocking genetic potential from the wild. Science 277:1063-1066.
24. Watkins-Chow D, Roller M, Newhouse MM, Buchberg AM (1996). Encyclopedia of the mouse genome V. Mouse chromosome 11. Mamm Genome 6:S201-S220.
25. Weber JL, May PE (1989). Abundant class of human DNA polymorphism which can be typed using the polymerase chain reaction. Am J Hum Genet 44:388-396.
26. Woodbury DM (1980). Convulsant drugs: mechanisms of action. Adv Neurol 27:249-303.