Depletion of the enteric nervous system by gene targeting results in haemorrhagic necrosis of the ileum

Gut

Volumn 43, Issue 6, 1998, Pages 742-743

  Macdonald, T T ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; GLIAL FIBRILLARY ACIDIC PROTEIN; MYELOPEROXIDASE; THYMIDINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BACTERIAL OVERGROWTH; CONTROLLED STUDY; ENTERITIS; GASTROINTESTINAL HEMORRHAGE; GENE TARGETING; HERPES SIMPLEX VIRUS; ILEITIS; ILEUM DISEASE; INTESTINE INNERVATION; INTESTINE NECROSIS; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 0031794816     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.43.6.742     Document Type: Article

References (6)

1. Sharkey KA, Coggins PJ, Tetzlaff W, et al. Distribution of growth associated protein B-50 (GAP-43) in the mammalian enteric nervous system. Neoruscience 1990;38:13-20.
2. De Giorgio R, Parodi JE, Brecha NC, et al. Nitric oxide producing neurones in the monkey and human digestive system. J Comp Neurol 1994;342:619-27.
3. Fan WQ, Smolich JJ, Wild J, et al. Nitric oxide modulates regional blood flow differences in the fetal gastrointestinal tract. Am J Physiol 1996;271:G598-604.
4. Klemm K, Moody FG. Regional intestinal blood flow and nitric oxide synthase inhibition during sepsis in the rat. Ann Surg 1998;227:126-33.
5. Kubota Y, Petras RE, Ottaway CA, et al. Colonic vasoactive intestinal peptide nerves in inflammatory bowel disease. Gastroenterology 1992;102: 1242-51
6. Simpson SJ, de Jong YP, Comiskey M, et al. T cells in mouse models of gut inflammation. In: MacDonald TT, ed. Mucosal T cells. Basel: Karger, 1998: 118-38.