Improvement of specificity in PSA-based screening by using PSA- transition zone density and percent free PSA in addition to total PSA levels

Prostate

Volumn 37, Issue 3, 1998, Pages 133-137

  Horninger, W ^a   Reissigl, A ^a   Klocker, H ^a   Rogatsch, H ^b   Fink, K ^a   Strasser, H ^a   Bartsch, G ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Percent free PSA; PSA transition zone density; PSA based screening; Repeat prostate biopsy

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER SCREENING; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; DRUG BLOOD LEVEL; EARLY DIAGNOSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE CANCER; PROSTATE HYPERTROPHY; TISSUE SPECIFICITY; ULTRASOUND;

BIOPSY; DIAGNOSIS, DIFFERENTIAL; HUMANS; MALE; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC HYPERPLASIA; PROSTATIC NEOPLASMS; REAGENT KITS, DIAGNOSTIC; RECTUM; SENSITIVITY AND SPECIFICITY;

EID: 0031794753     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19981101)37:3<133::AID-PROS1>3.0.CO;2-W     Document Type: Article

References (14)

1. Reissigl A, Klocker H, Pointner J, Fink K, Horninger W, Ennemoser O, Strasser H, Colleselli K, Höltl L, Bartsch G: Usefulness of the ratio free/total prostate specific antigen in addition to total PSA levels in prostate cancer screening. Urology 1996; 48:62-66.
2. Reissigl A, Klocker H, Pointner J, Ennemoser O, Falk M, Bartsch G: Improvement of prostate cancer screening by determination of the ratio free/total PSA in addition to PSA levels. Prostate 1997;30:243-247.
3. Catalona WJ, Smith DS, Wolfert RL, Wang TJ, Rittenhouse HG, Ratliff TL, Nadler RB: Evaluation of percentage of free serum prostate specific antigen to improve specificity of prostate cancer screening. JAMA 1995;274:1214-1220.
4. McNeal JE: The prostate gland: Morphology and pathobiology. Monogr Urol 1988;9:36-54.
5. Oesterling JE, Jacobson SJ, Chute CG, Guess HA, Girman CJ, Panser LA, Liber MM: Serum prostate specific antigen in a community based population of healthy men. Establishment of age specific reference ranges. JAMA 1993;270:860-864.
6. Benson MC, Whang IS, Olsson CA, McMahon DJ, Cooner WH: The use of prostate specific antigen density to enhance the predictive value of intermediate levels of serum prostate specific antigen. J Urol 1992;147:187-821.
7. Benson MC, Whang IS, Pantuck A, Ring K, Kaplan SA, Olsson CA, Cooner WH: Prostate specific antigen density. A means of distinguishing benign prostate hypertrophy and prostate cancer. J Urol 1992;147:815-816.
8. Bazinet M, Meshref AW, Trudel C, Aronson S, Peloquin F, Nachabe M, Begin LR, Elhilali MM: Prospective evaluation of prostate-specific antigen density and systematic biopsies for early detection of prostatic carcinoma. Urology 1994;43:44-52.
9. Rommel FM, Agusta VE, Breslin JA, Huffnagle HW, Pohl CE, Sieber PR, Stahl CA: The use of prostate specific antigen and prostate specific antigen density in the diagnosis of prostate cancer in a community based urology practice. J Urol 1994;151: 88-93.
10. Drawer MK, Aramburu EAG, Chen GL, Preston SD, Ellis WJ: The inability of prostate specific antigen index to enhance the predictive value of prostate specific antigen in the diagnosis of prostatic carcinoma. J Urol 1993;150:369-373.
11. Bare R, Hart L, McCullough DL: Correlation of prostate-specific antigen and prostate-specific antigen density with outcome of prostate biopsy. Urology 1994;43:191-196.
12. Presti JC, Hovey R, Carroll PR, Shinohara K: Prospective evaluation of prostate specific antigen and prostate specific antigen density in the detection of nonpalpable and stage T1C carcinoma of the prostate. J Urol 1996;156:1685-1690.
13. Kalish J, Cooner WH, Graham SD Jr: Serum PSA adjusted for volume of transitional zone (PSAT) is more accurate than PSA adjusted for total gland volume (PSAD) in detecting adenocarcinoma of the prostate. Urology 1994;43:601-606.
14. Zlotta AR, Djavan B, Marberger M, Schulman CC: Prostate specific antigen density of the transitional zone: A new effective parameter for prostate cancer prediction. J Urol 1997;157:1315-1321.