C-reactive protein as an indicator of sepsis

Intensive Care Medicine

Volumn 24, Issue 10, 1998, Pages 1052-1056

  Povoa P ^a   Almeida, E ^a   Moreira, P ^a   Fernandes, A ^a   Mealha, R ^a   Aragao A ^a   Sabino, H ^a  

^a HOSPITAL GARCIA DE ORTA   (Portugal)

Author keywords

C reactive; Protein; Sepsis

Indexed keywords

C REACTIVE PROTEIN;

ADULT; AGED; ARTICLE; BODY TEMPERATURE; CLINICAL ARTICLE; FEMALE; FOLLOW UP; HUMAN; INTENSIVE CARE UNIT; LEUKOCYTE COUNT; MALE; PROTEIN BLOOD LEVEL; SEPSIS; STATISTICAL ANALYSIS;

AGED; BIOLOGICAL MARKERS; BODY TEMPERATURE; C-REACTIVE PROTEIN; FEMALE; FEVER; HUMANS; LEUKOCYTE COUNT; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 0031794705     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050715     Document Type: Article

References (16)

1. Bone RC, Fisher CJ, Clemmer TP, Slotnuin GJ, Metz CA, Balk RA, the Methylprednisolone Severe Sepsis Study Group (1989) Sepsis syndrome: a valid clinical entity. Crit Care Med 17: 389-393
2. British Thoracic Society Research Committee (1987) Community-acquired pneumonia in adults in British hospitals in 1982-1983: a survey of actiology, mortality, prognostic factors and outcome. Q J Med 62: 195-220
3. Pepys MB, Baltz ML (1983) Acute phase proteins with special reference to C-reactive protein and related proteins (pentraxins) and serum amyloid A protein. Adv Immunol 34: 141-212
4. Okamura JM, Miyagi JM, Terada K, et al. (1990) Potential clinical applications of C-reactive protein. J Clin Lab Anal 4: 231-235
5. Castell JV, Gomez-Lechon MJ, David M, et al. (1990) Acute phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6. Hepalology 12: 1179-1186
6. Sim JE, March CD, Cosman D, et al. (1988) cDNA expression cloning of the IL-1 receptor, a member of the immunoglobulin super-family. Science 241: 585-589
7. Matson A, Soni N, Sheldon J (1991) C-reactive protein as a diagnostic test of sepsis in critically ill. Anaesth Intensive Care 19: 182-186
8. Schentag JJ, O'Keefe D, Marmion M, Weis PB (1984) C-reactive protein as an indicator of infection relapse in patients with abdominal sepsis. Arch Surg 119:300-304
9. Adnet F, Bekka R, Vicaut H, Lapostolle F, Giraudeaux V, Bismuth C, Baud F (1996) C-reactive protein (CRP) as an indicator to detect bacterial contamination of aspiration pneumonia (abstract). Intensive Care Med 22 (Suppl 3):S-319
10. Cox ML, Rudd AG, Gallimore R, Hodkinson HM, Pepys MB (1986) Realtime measurement of serum C-reactive protein in the management of infection in the elderly. Age Ageing 15: 257-266
11. Smith RP, Lipworth BJ, Cree IA, Spiers EM, Winter JH (1995) C-reactive protein: a clinical marker in community-acquired pneumonia. Chest 108: 1288-1291
12. Yentis SM, Soni N, Sheldon J (1995) C-reactive protein as an indicator of resolution of sepsis in the intensive care unit. Intensive Care Med 21: 602-605
13. Marshall JC, Cook DJ, Sibbald WJ, Roy PD, Christou NV (1992) The multiple organ dysfunction (MOD) score: a reliable descriptor of a complex clinical outcome (abstract). Crit Care Med 20:S80
14. ACCP/SCCM Consensus Conference (1992) Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 20: 864-874
15. Goldstcin H (1995) Models for repeated measures data. In: Harvey Goldstein, Kendall's Library of Statistics 3, Multi-level Statistical Models, 2nd edn. Arnold, London Sydney Auckland, pp 87-95
16. Vigushin DM, Pepys MB, Hawkins PN (1993) Metabolic and scintigraphic studies of radioiodinated human C-reactive protein in health and disease. J Clin Invest 90: 1351-1357