Structure-function analysis of a conserved aromatic cluster in the N-terminal domain of human epidermal growth factor

Protein Engineering

Volumn 11, Issue 11, 1998, Pages 1041-1050

  Murray, Mary Beth ^a   Tadaki, Douglas K ^d   Campion, Stephen R ^e   Lamerdin, John A ^b   Serpersu, Engin H ^b   Bradrick, Thomas D ^c   Niyogi, Salil K ^a  

^a OAK RIDGE NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d NAVAL MEDICAL RESEARCH INSTITUTE   (United States)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

Aromatic cluster of human EGF; Circular dichroism; Mutagenesis; NMR analysis; Receptor binding

Indexed keywords

AROMATIC COMPOUND; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; HISTIDINE; MUTANT PROTEIN; TYROSINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; HUMAN; HYDROPHOBICITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

EID: 0031794332     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.11.1041     Document Type: Article

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