Oral clonidine premedication enhances the pressor response to ephedrine during spinal anesthesia

Anesthesia and Analgesia

Volumn 87, Issue 6, 1998, Pages 1336-1339

  Goyagi, Toru ^a   Tanaka, Makoto ^b   Nishikawa, Toshiaki ^b  

^a TSUCHIURA KYODO GENERAL HOSPITAL   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CLONIDINE; EPHEDRINE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; HEMODYNAMIC MONITORING; HUMAN; PREMEDICATION; PRIORITY JOURNAL; SPINAL ANESTHESIA; VASOCONSTRICTION;

EID: 0031794132     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/00000539-199812000-00023     Document Type: Article

References (17)

1. Morgan P. The role of vasopressors in the management of hypotension induced by spinal and epidural anaesthesia. Can J Anaesth 1994;41:404-13.
2. Critchley LAH, Stuart JC, Conway F, Short TG. Hypotension during subarachnoid anaesthesia: haemodynamic effects of ephedrine. Br J Anaesth 1995;74:373-8.
3. Datta S, Alper MH, Ostheimer GW, Weiss JB. Method of ephedrine administration and nausea and hypotension during spinal anesthesia for cesarean section. Anesthesiology 1982;56:68-70.
4. Taivainen T. Comparison of ephedrine and etilefrine for the treatment of arterial hypotension during spinal anaesthesia in elderly patients. Acta Anaesthesiol Scand 1991;35:164-9.
5. Singh H, Liu J, Graines GY, White PF. Effect of oral clonidine and intrathecal fentanyl on tetracaine spinal block. Anesth Analg 1994;79:1113-6.
6. Ota K, Namiki A, Ujike Y, Takahashi I. Prolongation of tetracaine spinal anesthesia by oral clonidine. Anesth Analg 1992;75: 262-4.
7. Ota K, Namiki A, Iwasaki H, Takahashi I. Dosing interval for prolongation of tetracaine spinal anesthesia by oral clonidine in humans. Anesth Analg 1994;79:1117-20.
8. Ota K, Namiki A, Iwasaki H, Takahashi I. Dose-related prolongation of spinal anesthesia by oral clonidine in humans. Anesth Analg 1994;79:1121-5.
9. Azad A, Kats RL, Patel RV, et al. The effect of oral clonidine on the duration of lidocaine spinal anesthesia. Anesthesiology 1994;81:A944.
10. Goyagi T, Nishikawa T. Oral clonidine premedication enhances the quality of postoperative analgesia by intrathecal morphine. Anesth Analg 1996;82:1192-6.
11. Nishikawa T, Kimura T, Taguchi N, Dohi S. Oral clonidine premedication augments the pressor responses to intravenous ephedrine in awake or anesthetized patients. Anesthesiology 1991;74:705-10.
12. Tanaka M, Nishikawa T. Enhancement of pressor response to ephedrine following clonidine medication. Anaesthesia 1996;51: 123-7.
13. Inomata S, Nishikawa T, Kihara S, Akiyoshi Y. Enhancement of pressor response to intravenous phenylephrine following oral clonidine medication in awake and anaesthetised patients. Can J Anaesth 1995;42:119-25.
14. Nishikawa T, Tajima K, Kimura T, Satsumae T. Hemodynamic effects of oral clonidine premedication in lumbar epidural anesthesia. J Anesth 1996;10:248-51.
15. Filos KS, Patroni O, Goudas LC, et al. A dose-response study of orally administered clonidine as premedication in the elderly: evaluating hemodynamic safety. Anesth Analg 1993;77:1185-92.
16. Fujimura A, Ebihara A, Ohashi K, et al. Comparison of the pharmacokinetics, pharmacodynamics, and safety of oral (Catapres) and transdermal (M-5041T) clonidine in healthy subjects. J Clin Pharmacol 1994;34:260-5.
17. Lowenthal DT, Matzek KM, MacGregor TR. Clinical pharmacokinetics of clonidine. Clin Pharmacokinet 1988;14:287-310.