Migration of human keratinocytes in electric fields requires growth factors and extracellular calcium

Journal of Investigative Dermatology

Volumn 111, Issue 5, 1998, Pages 751-756

  Fang, K S ^a   Farboud, B ^a   Nuccitelli, R ^a   Isseroff, R R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bovine pituitary extract; Epidermal growth factor; Galvanotaxis; Motility; Wound current; Wound healing

Indexed keywords

CALCIUM; EGTAZIC ACID; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; HYPOPHYSIS EXTRACT; INSULIN;

ARTICLE; CELL MIGRATION; CONTROLLED STUDY; ELECTRIC FIELD; ELECTRODERMAL RESPONSE; ELECTROSTIMULATION; HUMAN; HUMAN CELL; KERATINOCYTE; NEWBORN; PRIORITY JOURNAL;

EID: 0031793971     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.1998.00366.x     Document Type: Article

References (65)

1. B. Alberts D. Bray J. Lewis M. Raff K. Roberts J.D. Watson Molecular Biology of the Cell 1989 Garland Publishing New York
2. G. Albrecht-Buehler The phagokinetic tracks of 3T3 cells Cell 11 1997 395 404
3. Y. Ando P.J. Jensen Epidermal growth factor and insulin-like growth factor I enhance keratinocyte migration J Invest Dermatol 100 1993 633 639
4. A.T. Barker L.F. Jaffe Jw Vanable Jr The glabrous epidermis of cavies contains a powerful battery Am J Physiol 242 1982 R358 R366
5. Y. Barrandon H. Green Cell migration is essential for sustained growth of keratinocyte colonies: the roles of transforming growth factor-alpha and epidermal growth factor Cell 50 1987 1131 1137
6. N.T. Bennett G.S. Schultz Growth factors and wound healing: biochemical properties of growth factors and their receptors Am J Surg 166 1993 74 81
7. S.T. Boyce R.G. Ham Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture J Invest Dermatol 81 1983 33s 40s
8. D. Breitkreutz H.J. Stark P. Plein M. Baur N.E. Fusenig Differential modulation of epidermal keratinization in immortalized (HaCaT) and tumorigenic human skin keratinocytes (HaCaT-ras) by retinoic acid and extracellular Ca2+ Differentiation 54 1993 201 217
9. M.J. Brown L.M. Loew Electric field-directed fibroblast locomotion involves cell surface molecular reorganization and is calcium independent J Cell Biol 127 1994 117 128
10. G.L. Brown L.B. Nanney J. Griffen Enhancement of wound healing by topical treatment with epidermal growth factor New Engl J Med 321 1989 76 79
11. F. Bussolino M.F. Di Renzo M. Ziche Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth J Cell Biol 119 1992 629 641
12. D. Cha P. O’brien E.A. O’toole D.T. Woodley L.G. Hudson Enhanced modulation of keratinocyte motility by transforming growth factor-alpha (TGF-alpha) relative to epidermal growth factor (EGF) J Invest Dermatol 106 1996 590 597
13. P. Chen K. Gupta A. Wells Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis J Cell Biol 124 1994 547 555
14. J.D. Chen M. Helmold J.P. Kim K.C. Wynn D.T. Woodley Human keratinocytes make uniquely linear phagokinetic tracks Dermatology 188 1994 6 12
15. J.D. Chen J.C. Lapiere D.N. Sauder C. Peavey D.T. Woodley Interleukin-1 alpha stimulates keratinocyte migration through an epidermal growth factor/transforming growth factor-alpha-independent pathway J Invest Dermatol 104 1995 729 733
16. M.C. Chiang Ej Cragoe Jr Jw Vanable Jr Intrinsic electric fields promote epithelialization of wounds in the newt, Notophthalmus viridescens Dev Biol 146 1991 377 385
17. RaF Clark Cutaneous tissue repair: basic biologic considerations J Am Acad Dermatol 13 1985 701 725
18. E.A. Clark J.S. Brugge Integrins and signal transduction pathways: the road taken Science 268 1995 233 239
19. N.W. DeLapp D.K. Dieckman Effect of basic fibroblast growth factor (bFGF) and insulin-like growth factors type I (IGF-I) and type II (IGF-II) on adult human keratinocyte growth and fibronectin secretion J Invest Dermatol 94 1990 777 780
20. H. Doong S. Dissanayake T.R. Gowrishankar M.C. LaBarbera R.C. Lee The 1996 Lindberg Award. Calcium antagonists alter cell shape and induce procollagenase synthesis in keloid and normal human dermal fibroblasts J Burn Care Rehabil 17 1996 497 514
21. C.A. Erickson R. Nuccitelli Embryonic fibroblast motility and orientation can be influenced by physiological electric fields J Cell Biol 98 1984 296 307
22. I.S. Foulds A.T. Barker Human skin battery potentials and their possible role in wound healing Br J Dermatol 109 1983 515 522
23. E. Fuchs Epidermal differentiation: the bare essentials J Cell Biol 111 1990 2807 2814
24. S. Giordano Z. Zhen E. Medico G. Gaudino F. Galimi P.M. Comoglio Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene Proc Natl Acad Sci USA 90 1993 649 653
25. D. Gospodarowicz G. Neufeld L. Schweigerer Fibroblast growth factor Mol Cell Endocrinol 46 1986 187 204
26. D.G. Greenhalgh K.H. Sprugel M.J. Murray R. Ross PDGF and FGF stimulate wound healing in the genetically diabetic mouse Am J Pathol 136 1990 1235 1246
27. 2+ J Cell Biol 117 1992 1109 1117
28. J.J. Grzesiak M.D. Pierschbacher Changes in the concentrations of extracellular Mg++ and Ca++ down-regulate E-cadherin and up-regulate alpha 2 beta 1 integrin function, activating keratinocyte migration on type I collagen J Invest Dermatol 104 1995 768 774
29. J.J. Grzesiak M.D. Pierschbacher Shifts in the concentrations of magnesium and calcium in early porcine and rat wound fluids activate the cell migratory response J Clin Invest 95 1995 227 233
30. H. Hennings K. Holbrook P. Steinert S. Yuspa Growth and differentiation of mouse epidermal cells in culture: effects of extracellular calcium Current Problems in Dermatology 10 1980 3 25
31. H. Hennings D. Michael C. Cheng P. Steinert K. Holbrook S.H. Yuspa Calcium regulation of growth and differentiation of mouse epidermal cells in culture Cell 19 1980 245 254
32. C.M. Illingworth A.T. Barker Measurement of electrical currents emerging during the regeneration of amputated fingertip in children Clin Phys Physiol Meas 1 1980 87 89
33. R.R. Isseroff V.A. Ziboh R.S. Chapkin D.T. Martinez Conversion of linoleic acid into arachidonic acid by cultured murine and human keratinocytes J Lipid Res 28 1987 1342 1349
34. E.W. Johnson S.F. Meunier C.J. Roy N.L. Parenteau Serial cultivation of normal human keratinocytes: a defined system for studying the regulation of growth and differentiation In Vitro Cell Dev Biol 28A 1992 429 435
35. W.D. Ju J.T. Schiller M.K. Kazempour D.R. Lowy TGF alpha enhances locomotion of cultured human keratinocytes J Invest Dermatol 100 1993 628 632
36. J.P. Kim K. Zhang J.D. Chen K.C. Wynn R.H. Kramer D.T. Woodley Mechanism of human keratinocyte migration on fibronectin: unique roles of RGD site and integrins J Cell Physiol 151 1992 443 450
37. J.F. Krane D.P. Murphy D.M. Carter J.G. Krueger Synergistic effects of epidermal growth factor (EGF) and insulin-like growth factor I/somatomedin C (IGF-I) on keratinocyte proliferation may be mediated by IGF-I transmodulation of the EGF receptor J Invest Dermatol 96 1991 419 424
38. W.S. Krawczyk A pattern of epidermal cell migration during wound healing J Cell Biol 49 1971 247 263
39. T.S. Lange A.K. Bielinsky K. Kirchberg I. Bank K. Herrmann T. Krieg K. Scharffetter-Kochanek Mg2+ and Ca2+ differentially regulate beta 1 integrin-mediated adhesion of dermal fibroblasts and keratinocytes to various extracellular matrix proteins Exp Cell Res 214 1994 381 388
40. M.A. Lawson F.R. Maxfield Ca (2+) – and calcineurin-dependent recycling of an integrin to the front of migrating neutrophils Nature 376 1995 75 79
41. I.M. Leigh F.M. Watt The culture of human epidermal keratinocytes I.M. Leigh E.B. Lane F.M. Watt The Keratinocyte Handbook 1994 Cambridge University Press Cambridge
42. L. Li F.H. Kruszewski K. Punnone R.W. Tucker S.H. Yuspa H. Hennings Strontium induces murine keratinocyte differentiation in vitro in the presence of serum and calcium J Cell Physiol 154 1993 643 653
43. S.E. Lynch R.B. Colvin H.N. Antoniades Growth factors in wound healing. Single and synergistic effects on partial thickness porcine skin wound J Clin Invest 84 1989 640 646
44. P. Martin Wound healing-aiming for perfect skin regeneration Science 276 1997 75 81
45. L.J. McCawley P. O’brien L.G. Hudson Overexpression of the epidermal growth factor receptor contributes to enhanced ligand-mediated motility in keratinocyte cell lines Endo 138 1997 121 127
46. P.L. McNeil L. Muthukrishnan E. & AdaP Warder Growth factors are released by mechanically wounded endothelial cells J Cell Biol 109 1989 811 822
47. B.J. Nickoloff R.S. Mitra B.L. Riser V.M. Dixit J. Varani Modulation of keratinocyte motility Am J Pathol 132 1988 543 551
48. K.Y. Nishimura R.R. Isseroff R. Nuccitelli Human keratinocytes migrate to the negative pole in direct current electric fields comparable to those measured in mammalian wounds J Cell Sci 109 1996 199 207
49. R. Nuccitelli Physiological electric fields can influence cell motility, growth, and polarity Adv Cell Biol 2 1988 213 233
50. R. Nuccitelli T. Smart J. Ferguson Protein kinases are required for embryonic neural crest cell galvanotaxis Cell Motil Cytoskeleton 24 1993 54 66
51. E.J. O’keefe R.A. Briggaman B. Herman Calcium-induced assembly of adherens junctions in keratinocytes J Cell Biol 105 1987 807 817
52. B.K. Pilcher J.A. Dumin B.D. Sudbeck S.M. Krane H.G. Welgus W.C. Parks The activity of collagenase-1 is required for keratinocyte migration on a type I collagen matrix J Cell Biol 137 1997 1445 1457
53. J.G. Rheinwald H. Green Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes Nature 265 1977 421 424
54. Y. Sarret D.T. Woodley K. Grigsby K. Wynn J. Oke Human keratinocyte locomotion: the effect of selected cytokines J Invest Dermatol 98 1992 12 16
55. G. Schultz D.S. Rotatori W. Clark EGF and TGF-alpha in wound healing and repair J Cell Biochem 45 1991 346 352
56. G.S. Schultz M. White R. Mitchell G. Brown J. Lynch D.R. Twardzik G.J. Todaro Epithelial wound healing enhanced by transforming growth factor alpha and vaccinia growth factor Science 235 1987 350 352
57. G.R. Sharpe C. Fisher J.I. Gillespie J.R. Greenwell Growth and differentiation stimuli induce different and distinct increses in intracellular free calcium in human keratinocytes Arch Dermatol Res 284 1993 445 450
58. G.R. Sharpe J.I. Gillespie J.R. Greenwell An increase in intracellular free calcium is an early event during differentiation of cultured human keratinocytes FEBS Lett 254 1989 25 28
59. D.M. Sheridan R.R. Isseroff R. Nuccitelli Imposition of a physiologic DC electric field alters the migratory response of human keratinocytes on extracellular matrix molecules J Invest Dermatol 106 1996 642 646
60. H. Steenfos Growth factors and wound healing Scand J Plast Reconstr Hand Surg 28 1994 95 105
61. W.R. Taylor A.H. Greenberg E.A. Turley J.A. Wright Cell motility, invasion, and malignancy induced by overexpression of K-FGF or bFGF Exp Cell Res 204 1993 295 301
62. R. Tsuboi C. Sato Y. Kurita D. Ron J.S. Rubin H. Ogawa Keratinocyte growth factor (FGF-7) stimulates migration and plasminogen activator activity of normal human keratinocytes J Invest Dermatol 101 1993 49 53
63. E. Williams F. Walsh P. Doherty Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth J Cell Biol 124 1994 1029 1237
64. D.T. Woodley J.D. Chen J.P. Kim Y. Sarret T. Iwasaki Y.H. Kim J. Oke Reepithelialization: human keratinocyte locomotion Dermatol Clin 11 1993 641 646
65. S.H. Yuspa A.E. Kilkenny P.M. Steinert D.R. Roop Expression of murine epidermal differentiation markers in tightly regulated by restricted extracellular calcium concentrations in vitro J Cell Biol 109 1989 1207 1217