Systolic coronary flow impediment in the dog: Role of ventricular pressure and contractility

Experimental Physiology

Volumn 83, Issue 6, 1998, Pages 821-831

  Pagliaro, Pasquale ^b   Gattullo, Donatella ^a   Linden, Ronald J ^d   Losano, Gianni ^a   Westerhof, Nico ^c  

^a UNIVERSITY OF TURIN   (Italy)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DOG; EXTRACORPOREAL CIRCULATION; HEART LEFT VENTRICLE PRESSURE; HEART VENTRICLE CONTRACTILITY; HEART VENTRICLE VOLUME; NONHUMAN; PERFUSION PRESSURE; SYSTOLIC BLOOD PRESSURE; VASODILATATION;

EID: 0031792893     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.1998.sp004162     Document Type: Article

References (23)

1. BOUMA, P., SIPKEMA, P. & WESTERHOF, N. (1994). Vasomotor tone affects diastolic and systolic coronary flow and flow impediment by contraction similarly. American Journal of Physiology 266, H1944-1950.
2. BRUINSMA, P., ARTS, T., DANKELMAN, J. & SPAAN, J. A. (1988). Model of the coronary circulation based on pressure dependence of coronary resistance and compliance. Basic Research in Cardiology 83, 510-524.
3. CHILIAN, W. M., LAYNE, S. M., KLAUSNER, E. C., EASTHAM, C. L. & MARCUS, M. L. (1989). Redistribution of coronary microvascular resistance produced by dipyridamole. American Journal of Physiology 856, H383-390.
4. DOWNEY, H. F. & KIRK, E. S. (1975). Inhibition of coronary flow by a vascular waterfall mechanism. Circulation Research 36, 753-760.
5. FEIGL, E. O. (1983). Coronary Physiology, Physiological Reviews 63, 1-203.
6. FUJII, M., NUNO, D. W., LAMPING, K. G., DELLSPERGER, K. C., EASTHAM, C. L. & HARRISON, D. G. (1992). Effect of hypertension and hypertrophy on coronary microvascular pressure. Circulation Research 71, 120-126.
7. GATTULLO, D., LINDEN, R. J., LOSANO, G., PAGLIARO, P. & WESTERHOF, N. (1994). Ventricular distension and diastolic coronary blood flow in the anaesthetized dog. Basic Research in Cardiology 88, 340-349.
8. GREGG, D. E., KHOURI, E. M. & RAYFORD, C. R. (1965). Systemic and coronary energetics in the resting dog. Circulation Research 16, 102-113.
9. HALPERIN, H. R., CHEW, P. H., WEISFELDT, M. L., SAGAWA, K., HUMPHREY, J. D. & YIN, F. C. P. (1987). Transverse stiffness: a method for estimation of myocardial wall stress. Circulation Research 61, 695-703.
10. KLASSEN, G. & ZBOROWSKA-SLUIS, D. T. (1979). The effect of myocardial force on coronary transmural flow distribution. Cardiovascular Research 13, 365-369.
11. KLOCKE, F. J. (1976). Coronary blood flow in man. Progress in Cardiovascular Disease 19, 117-166.
12. KOUWENHOVEN, E., VERGROESEN, I., HAN, Y. & SPAAN, J. A. E. (1992). Retrograde coronary flow is limited by time-varying elastance. American Journal of Physiology 263, H484-490.
13. KRAMS, R., SIPKEMA, P. & WESTERHOF, N. (1989a). The varying elastance concept may explain coronary systolic flow impediment. American Journal of Physiology 257, H1471-1479.
14. KRAMS, R., SIPKEMA, P. & WESTERHOF, N. (1989b). Contractility is the main determinant of coronary systolic flow impediment. American Journal of Physiology 257, H1936-1944.
15. LIN, D. H. & YIN, F. C. P. (1995). Biaxial mechanical properties of barium-activated left ventricular myocardium. FASEB Journal 9, A559 (abstract).
16. McMAHON, N. C., DRINKHILL, M. J. & HAINSWORTH, R. (1996). Reflex vascular responses from aortic arch, carotid sinus, and coronary baroreceptors in the anaesthetized dog. Experimental Physiology 81, 397-408.
17. REASER, J., LIVINGSTON, J. Z., HALPERIN, H. R., SIPKEMA, P., KRAMS, R. & YIN, F. C. P. (1990). Effect of wall stretch on coronary hemodynamics in isolated canine interventricular septum. American Journal of Physiology 259, H1869-1880.
18. SPAAN, J. A. E., BREULS, N. W. P. & LAIRD, J. D. (1981). Diastolic-systolic coronary flow differences are caused by intramyocardial pump action in the anaesthetized dog. Circulation Research 49, 584-593.
19. SUGA, H., SAGAWA, K. & SHOUKAS, A. A. (1973). Load impedance of the instantaneous pressure-volume ratio of the canine left ventricle and effects of epinephrine and heart rate on the ratio. Circulation Research 32, 314-322.
20. TODAKA, K., OGINO, K., GU, A. & BURKHOFF, D. (1998). Effect of ventricular stretch on contractile stretch calcium transient, cAMP in intact canine hearts. American Journal of Physiology 274, H990-1000.
21. TRIMBLE, J. & DOWNEY, J. (1979). Contribution of myocardial contractility to myocardial perfusion. American Journal of Physiology 236, H121-126.
22. VIS, M. A., SIPKEMA, P. & WESTERHOF, N. (1997a). Modeling pressure-flow relations in cardiac muscle in diastole and systole. American Journal of Physiology 272, H1516-1526.
23. VIS, M. A., SIPKEMA, P. & WESTERHOF, N. (1997b). Compression of intramyocardial arterioles during cardiac contraction is attenuated by accompanying venules. American Journal of Physiology 273, H1003-1011.