Radiosynthesis of [18F]N-(4-Phenylbutyl)-4-(4-fluorobenzoyl)piperidine for studying serotonin 5-HT(2A) receptors

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 41, Issue 10, 1998, Pages 941-949

  Hashimoto, Kenji ^a,b,e   Hatano, Kentaro ^c   Minabe, Yoshio ^a   Iyo, Masaomi ^b   Taniguchi, Masahiko ^d   Hoshino, Osamu ^d   Sakiyama, Yojiro ^c   Kawasumi, Yasuhiro ^c  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (Japan)

^c NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^d TOKYO UNIVERSITY OF SCIENCE   (Japan)

^e Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

Fluorine 18; Positron emission tomography (PET); Radiolabeling; Serotonin 5 HT(2A) receptor

Indexed keywords

FLUORINE; FLUORINE COMPOUNDS; POSITRONS;

FLUORINE-18; HIGH AFFINITY; IN-VIVO; KRYPTOFIX 222; POSITRON EMISSION TOMOGRAPHY; RADIOLABELLING; RADIOSYNTHESIS; SELECTIVE BINDING; SEROTONIN 5-HT(2A) RECEPTOR; VIVO STUDIES;

POSITRON EMISSION TOMOGRAPHY;

FLUORINE 18; N (4 PHENYLBUTYL) 4 (4 FLUOROBENZOYL)PIPERIDINE; PIPERIDINE DERIVATIVE; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RECEPTOR AFFINITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALIA;

EID: 0031792710     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(1998100)41:10<941::AID-JLCR151>3.0.CO;2-6     Document Type: Article

References (24)

1. Zifa E. and Fillion G. - Pharmacol. Rev. 44: 401 (1992)
2. Fuller R.W. - J. Clin. Psychiatry 53 (10 suppl): 36 (1992)
3. Dubovsky S.L. and Thomas M. - J. Clin. Psychiatry 56 (suppl 2): 38 (1995)
4. Arranz M., Collier D., Sodhi M., Ball D., Roberts G., Price J., Sham P. and Kerwin R. - Lancet 346: 281 (1995)
5. Busatto G.F. - Eur. J. Nucl. Med 23: 867 (1996)
6. Crouzel C., Guillaume M., Barre L., Lemaire C. and Pike V.W. - Nucl. Med. Biol. 19: 857 (1992)
7. Berridge M., Comar D., Crouzel C. and Baron J.C. - J. Labelled Compd. Radiopharm. 20: 73 (1983)
8. Burns H.D., Dannals R.F., Langstrom B., - J. Nucl. Med. 25: 1222 (1984)
9. Lever J.R., Dannals R.F., Wilson A.A., Ravert H.T., Schefell U., Hoffman B.J., Hartig P.R., Wong D.F. and Wagner H.N. - Nucl. Med. Biol 16: 697 (1989)
10. Shiue C.Y., Fowler J.S., Wolf A.P., Watanabe M and Arnett C.D. - J. Nucl. Med. 26: 181 (1985)
11. Crouzel C., Venet M., Irie T., Sanz G. and Boullais C. - J. Labelled Compd. Radiopharm. 25: 403 (1988)
12. Lemaire C., Cantineau R., Guillaume M., Plenevaux A. and Christiaens L. - J. Nucl. Med. 32: 2266 (1991)
13. Biver F., Goldman S., Luxen A., Monclus M., Forestini M., Mendlewicz J. and Lotstra F. - Eur. J. Nucl. Med. 21: 937 (1994)
14. Lasne M.C., Barre L., Huard C., Le Secq B. and Collins M. - Appl. Radiat. Isot. 45: 1085 (1994)
15. Tan P., Fowler J.S., Ding Y.-S. and Schlyer D.J. - J. Labelled Compd Radiopharm. 36: 719 (1995)
16. Lundkvist C., Halldin C., Ginovart N., Nyberg S., Swahn C.-G., Varr A.A., Brunner F. and Farde L. - Life Sciences 58: PL 187 (1996)
17. Herndon J.H., Ismaiel A., Ingher S.P., Teitler I.M. and Glennon R.A. - J. Med. Chem. 35: 4903 (1992)
18. Hamatcher, K., Blessing, G. and Nebeling, B. - Appl Radiat Isot. 41: 49 (1990)
19. Lemaire C., Plenevaux A., Del Fiore G., Aerts J., Le Bars D. and Comar D. - J. Labelled. Compds. Radiopharm. 37: 723 (1995)
20. Iwata R., Ido T., Brady F., Takahashi T. and Ujiie A. - Appl. Radiat. Isot. 35: 979 (1987)
21. Fajolles C., Boireau A., Ponchant M. and Laduron P.M. - Eur. J. Pharmacol. 216: 53 (1992)
22. Hashimoto K., Narita N., Tomitaka S., Iyo M. and Minabe Y. - Life Sciences 60: 2245 (1997)
23. Hashimoto K., Hatano K., Taniguchi M. and Hoshino O. - NMCC Annual Report 2: 194 (1994)
24. Hashimoto K., Hatano K., Taniguchi M. and Hoshino O. - NMCC Annual Report 3: 167 (1995)