A single midnight serum cortisol measurement distinguishes Cushing's syndrome from pseudo-Cushing states

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 4, 1998, Pages 1163-1167

  Papanicolaou, Dimitris A ^a   Yanovski, Jack A ^a   Cutler Jr , Gordon B ^a,b   Chrousos, George P ^a   Nieman, Lynnette K ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

17 HYDROXYCORTICOSTEROID; GLUCOCORTICOID; HYDROCORTISONE;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CIRCADIAN RHYTHM; CONTROLLED STUDY; CUSHING SYNDROME; CUSHINGOID SYNDROME; DIAGNOSTIC ACCURACY; FEMALE; HUMAN; HUMAN TISSUE; HYDROCORTISONE BLOOD LEVEL; HYDROCORTISONE URINE LEVEL; MAJOR CLINICAL STUDY; MALE; NIGHT; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; CHILD; CHILD, PRESCHOOL; CIRCADIAN RHYTHM; CUSHING SYNDROME; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; HYDROCORTISONE; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; ROC CURVE; SECRETORY RATE;

EID: 0031792497     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.83.4.1163     Document Type: Article

References (29)

1. Orth DN. 1995 Cushing's syndrome [published erratum appears in N Engl J Med 1995 Jun 1;332(22):1527]. N Engl J Med. 332:791-803.
2. Gold PW, Loriaux DL, Roy A, et al. 1986 Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications. N Engl J Med. 314:1329-1335.
3. Lamberts SW, Klijn JG, de Jong FH, Birkenhager JC. 1979 Hormone secretion in alcohol-induced pseudo-Cushing's syndrome. Differential diagnosis with Cushing disease. JAMA. 242:1640-1643.
4. Wand GS, Dobs AS. 1991 Alterations in the hypothalamic-pituitary-adrenal axis in actively drinking alcoholics. J Clin Endocrinol Metab. 72:1290-1295.
5. Smith MA, Kling MA, Whitfield HJ, et al. 1989 Corticotropin-releasing hormone: from endocrinology to psychobiology. Horm Res. 31:66-71.
6. Tsigos C, Young RJ, White A. 1993 Diabetic neuropathy is associated with increased activity of the hypothalamic-pituitary-adrenal axis. J Clin Endocrinol Metab. 76:554-558.
7. Roy MS, Roy A, Gallucci WT, et al. 1993 The ovine corticotropin-releasing hormone-stimulation test in type I diabetic patients and controls: suggestion of mild chronic hypercortisolism. Metabolism. 42:696-700.
8. Yanovski JA, Cutler GBJ, Chrousos GP, Nieman LK. 1993 Corticotropin-releasing hormone stimulation following low-dose dexamethasone administration. A new test to distinguish Cushing's syndrome from pseudo-Cushing's states. JAMA. 269:2232-2238.
9. Tsigos C, Papanicolaou DA, Chrousos GP. 1995 Advances in the diagnosis and treatment of Cushing's syndrome. Bailliere Clin Endocrinol Metab. 9:315-336.
10. Pavlatos FC, Smilo RP, Forsham PH. 1965 A rapid screening test for Cushing's syndrome. JAMA. 193:720-723.
11. Crapo L. 1979 Cushing's syndrome: a review of diagnostic tests. Metabolism. 28:955-977.
12. Murphy BE. 1991 Steroids and depression. J Steroid Biochem Mol Biol. 38:537-559.
13. Meikle AW, Lagerquist LG, Tyler FH. 1975 Apparently normal pituitary-adrenal suppressibility in Cushing's syndrome: dexamethasone metabolism and plasma levels. J Lab Clin Med. 86:472-478.
14. Terzolo M, Borretta G, Ali A, et al. 1995 Misdiagnosis of Cushing's syndrome in a patient receiving rifampicin therapy for tuberculosis [published erratum appears in Horm Metab Res 1995 May;27(5):261]. Horm Metab Res. 27:148-150.
15. Yanovski JA, Cutler Jr GB, Chrousos GP, Nieman LK. Prospective evaluation of the dexamethasone-suppressed corticotropin-releasing hormone test in the differential diagnosis of Cushing syndrome and pseudo-Cushing states. Proc of the 77th Annual Meet of The Endocrine Soc. 1995; 99.
16. Krieger DT, Allen W, Rizzo F, Krieger HP. 1971 Characterization of the normal temporal pattern of plasma corticosteroid levels. J Clin Endocrinol Metab. 32:266-284.
17. Pirich K, Vierhapper H. 1988 24-hour serum concentration profile of cortisol in patients with Cushing's disease. Exp Clin Endocrinol. 92:275-279.
18. Follenius M, Brandenberger G, Hietter B. 1982 Diurnal cortisol peaks and their relationships to meals. J Clin Endocrinol Metab. 55:757-761.
19. Swets JA. 1988 Measuring the accuracy of diagnostic systems. Science. 240:1285-1293.
20. Friedman TC, Yanovski JA. 1995 Morning plasma free cortisol: inability to distinguish patients with mild Cushing syndrome from patients with pseudo-Cushing states. J Endocrinol Invest. 18:696-701.
21. Glass AR, Zavadil III AP, Halberg F, Cornelissen G, Schaaf M. 1984 Circadian rhythm of serum cortisol in Cushing's disease. J Clin Endocrinol Metab. 59:161-165.
22. Tourniaire J, Chalendar D, Rebattu B, et al. 1986 The 24-h cortisol secretory pattern in Cushing's syndrome. Acta Endocrinol (Copenh). 112:230-237.
23. Shimatsu A, Kato Y, Sakami H, Nakai Y, Imura H. 1988 Phase-shifted diurnal rhythm of cortisol secretion in a patient with Cushing's syndrome due to adrenocortical adenoma. Endocrinol Jpn. 35:261-266.
24. Newell-Price J, Trainer P, Perry L, Wass J, Grossman A, Besser M. 1995 A single sleeping midnight cortisol has 100% sensitivity for the diagnosis of Cushing's syndrome. Clin Endocrinol (Oxf). 43:545-550.
25. Atkinson AB, Kennedy AL, Carson DJ, Hadden DR, Weaver JA, Sheridan B. 1985 Five cases of cyclical Cushing's syndrome. Br Med J (Clin Res Ed). 291:1453-1457.
26. Streeten DHP, Anderson Jr GH, Dalakos T, Joachimpillai AD. 1997 Intermittent hypercortisolism: a disorder strikingly prevalent after hypophysial surgical procedures. Endocr Pract. 3:123-129.
27. Velkeniers B, Beckers A, Stevenaert A, Smits J, Finne E, Vanhaelst L. 1991 Cyclical Cushing's disease. A case report. Pathol Res Pract. 187:603-607.
28. Nieman LK, Cutler Jr GB. The sensitivity of the urine free cortisol measurement as a screening test for Cushing's syndrome. Proc of the 72nd Annual Meet of The Endocrine Soc. 1990; 230.
29. Atkinson AB, McCance DR, Kennedy L, Sheridan B. 1992 Cyclical Cushing's syndrome first diagnosed after pituitary surgery: a trap for the unwary Clin Endocrinol (Oxf). 36:297-299.