Evidence for multiple enzyme site involvement in the modulation of thrombin activity by products of prothrombin proteolysis

Biophysical Chemistry

Volumn 75, Issue 3, 1998, Pages 187-199

  Shi, Fang ^a   Hogg, Philip J ^a   Winzor, Donald J ^b   Jackson, Craig M ^a  

^a AMERICAN RED CROSS BLOOD SERVICES   (United States)

^b Funct Eng   (Australia)

Author keywords

Blood coagulation; Fragment 1; Fragment 2; Proteolysis; Thrombin inhibition; Thrombin modulation

Indexed keywords

PROTHROMBIN; THROMBIN;

ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME MODIFICATION; MICHAELIS CONSTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ALLOSTERIC SITE; CATALYTIC DOMAIN; CHEMISTRY, PHYSICAL; CHROMOGENIC COMPOUNDS; ENZYME PRECURSORS; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; PROTHROMBIN; SUBSTRATE SPECIFICITY; THROMBIN;

EID: 0031791946     PISSN: 03014622     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-4622(98)00205-1     Document Type: Article

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