The S100B protein inhibits phosphorylation of GFAP and vimentin in a cytoskeletal fraction from immature rat hippocampus

Neurochemical Research

Volumn 23, Issue 10, 1998, Pages 1259-1263

  Ziegler, Denize R ^a   Innocente, Carla E ^a   Leal, Rodrigo B ^b   Rodnight, Richard ^a   Gonçalves, Carlos A ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Cytoskeleton; GFAP; Hippocampus; Protein phosphorylation; S100B protein; Vimentin

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM; CALCIUM BINDING PROTEIN; CALMODULIN; CYCLIC AMP; EGTAZIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERMEDIATE FILAMENT PROTEIN; MAGNESIUM CHLORIDE; PROTEIN S 100; VIMENTIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; CYTOSKELETON; FEMALE; GLIA; HIPPOCAMPUS; IMMATURITY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; CALCIUM-BINDING PROTEINS; CYTOSKELETON; FEMALE; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; MALE; NERVE GROWTH FACTORS; PHOSPHORYLATION; RATS; RATS, WISTAR; S100 PROTEINS; VIMENTIN;

ANIMALIA; HIPPOCAMPUS HIPPOCAMPUS;

EID: 0031791750     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020740115790     Document Type: Article

References (20)

1. Fanò, G., Biocca, S., Fulle, S., Mariggiò, Belia, S., and Calissano, P. 1995. The S-100: A protein family in search of a function. Prog. Neurobiol. 46:71-82.
2. Kligman, D., and Hilt, D. C. 1988. The S100 protein family. Trends Biochem. Sci. 13:437-443.
3. 2+-induced disassembly of brain microrubule proteins in vitro. FEBS Lett. 147:165-168.
4. 2+-calmodulin-dependent protein kinase II. J. Biol. Chem. 263:5876-5883.
5. Selinfreund, R. H., Barger, S. W., Welsh, M. J., and Van Eldik, L. J. 1990. Antisense inhibition of glial S-100b production results in alterations of cell morfology, cytoskeletal reorganization and cell proliferation. J. Cell Biol., 111:2021-2028.
6. Bianchi, R., Garbuglia, M., Verzini, M., Giambuco, I., Ivanenkov, V. V., Dimlich, R. V., Jamieson, G. A., and Donato, R. 1996. S-100 (and) binding peptide (TRTK-12) blocks S-100/GFAP interaction: identification of a putative target epitope within the head domain of GFAP. Biochim. Biophys. Acta. 1313:258-267.
7. 2+-dependent manner. J. Biol. Chem. 268:12669-12674.
8. Patel, J., Marangos, P. J., Heydom, W. E., Chang, G., Verma, A., and Jacobowitz, D. 1983. S-100-mediated inhibition of brain protein phosphorylation. J. Neurochem. 41:1040-1045.
9. Baudier, J., Mochly-Rosen, D., Newton, A., Lee, S., Koshland, D. E., and Cole, R. D. 1987. Comparasion of S-100b protein with calmodulin: Interaction with mellitin and microtubule-associated proteins and inhibition of phosphorylation of proteins by protein kinase C. Biochemistry 2:2889-2893.
10. Hagiwara, M., Ochiai, M., Owada, K., Tanaka, T., and Hidaka, H. 1988. Modulation of tyrosine phosphorylation of p36 and other substrates by the S-100 protein. J. Biol. Chem. 263:6438-6441.
11. Sheu, F.-S., Azmitia, E. C., Marshak, D. R., Parker, P. J., and Routtenberg, A. 1994. Glial-derived S100b protein selectively inhibits recombinant protein kinase C (PKC) phosphorylation of neuron-specific protein F1/GAP43. Mol. Brain Res. 21:62-66.
12. Rodnight, R., Gonçalves, C. A., Wofchuk, S. T., and Leal, R. 1997. Control of the phosphorylation of astrocyte marker GFAP in the immature rat hippocampus by glutamate nad calcium ions: possible key factor in astrocytic plasticity. Braz. J. Med. Biol. Res. 30:325-338.
13. Leal, R., Gonçalves, C. A., and Rodnight, R. 1997. The change in external calcium-dependence of the phosphorylation of glial fibrillary acidic protein during development is not due to a change in kinase activity: a study using tryptic phosphopeptide mapping. Dev. Brain Res. 104:1-10.
14. Harrison, B. C., and Mobley, P. L. 1992. Phosphorylation of glial fibrillary acidic protein and vimentin by cytoskeletal-associated intermediate filament protein kinase activity in astrocytes. J. Neurochem. 58:320-327.
15. Rodnight, R., Zamani, R., and Tweedale, A. 1988. An investigation of the experimental conditions for studying protein phosphorylation in micro-slices of rat brain by two-dimensional electrophoresis. J. Neurosci. Meth. 24:27-38.
16. Gonçalves, C. A., and Rodnight, R. 1992. Apparent identity of ppH-47, a protein highly phosphorylated in the hippocampus, with a form of glial fibrillary acidic protein. Neuroscience Res. Commun. 11:109-117.
17. Donato, R. 1991. Perspectives in S-100 protein biology. Cell Calcium. 12:713-721.
18. Chen, W.-J., and Liem, R. H. K. 1994. The endless story of glial fibrillary acidic protein. J. Cell Biol. 107:2299-2311.
19. 2+/S100 regulation of giant protein kinases. Nature 380:636-639.
20. Inagaki, M., Matsuoka, Y., Tsujimura, K., Ando, S., Tokui T., Takahashi, T., and Inagaki, N. 1996. Dynamic property of intermediate filaments: regulation by phosphorylation. BioEssays 18: 481-487.