In vitro approach to investigating the phototoxicity of the diuretic drug triamterene

Toxicology in Vitro

Volumn 12, Issue 6, 1998, Pages 661-667

  Vargas, F ^a   Fuentes, A ^a   Sequera, J ^b   Mendez H ^b   Fraile, G ^c   Velasquez M ^c   Medina, R ^c  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b UNIVERSIDAD SIMÓN BOLÍVAR   (Venezuela)

^c UNIVERSIDAD DE CARABOBO   (Venezuela)

Author keywords

Diuretics; Photohaemolysis; Phototoxicity; Singlet oxygen; Triamterene

Indexed keywords

1,4 DIAZABICYCLO[2.2.2]OCTANE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); BUFFER; BUTYLATED HYDROXYANISOLE; DIURETIC AGENT; FURFURYL ALCOHOL; GLUTATHIONE; HUMAN SERUM ALBUMIN; HYDROCHLOROTHIAZIDE PLUS TRIAMTERENE; LINOLEIC ACID; METHANOL; PHOSPHATE; SINGLET OXYGEN; SODIUM AZIDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TRIAMTERENE;

ARTICLE; CONTROLLED STUDY; HEMOLYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MONONUCLEAR CELL; PHOTODEGRADATION; PHOTOLYSIS; PHOTOTOXICITY; POLYMORPHONUCLEAR CELL; RISK ASSESSMENT; ULTRAVIOLET A RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 0031790976     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(98)00057-5     Document Type: Article

References (18)

1. 2) in illuminated solutions of p-amino benzoic acid (PABA). Journal of Photochemistry and Photobiology B: Biology 32, 33-38.
2. Alvarez S. and Boveris A. (1993) Induction of antioxidant enzymes and DT-diaphorase in human blood mononuclear cells by light stress. Archives of Biochemistry and Biophysics 305, 247-251.
3. Costanzo L. L., De Guidi G., Condorelli G., Cambria A. and Fama M. (1989) Molecular mechanism of drug photosensitization-II. Photohemolysis sensitized by ketoprofen. Photochemistry and Photobiology 50, 359-365.
4. Darken M. and McBurney E. (1988) Subacute cutaneous lupus erythema-tosus-like drug eruption due to combination diuretic hydrochloro-thiazide and triamterene. Journal of the American Academy of Dermatology 18, 38-42.
5. Fernández de C. L., Bernaola G., Fernández E., Leanizbarrutia I. and Muñoz D. (1987) Photodermatitis from triamterene. Contact Dermatitis 17, 114-115.
6. Gollnick K. and Griesbeck A. (1983) [4 + 2]-Cycloaddition of singlet oxygen to 2,5-dimethylfuran: isolation and reactions of the monomeric and dimeric endoperoxides. Angewante Chemie International (Ed. in English) 22, 726-728.
7. Haag W. R., Hoigne J., Gassman E. and Braun A. D. (1984) Singlet oxygen in surface waters - part I: furfuryl alcohol as a trapping agent. Chemosphere 13, 631-640.
8. Johnson B. E., Walker E. M. and Hetherington A. (1986) In vitro models for cutaneous phototoxicity. In Skin Models. Edited by R. Marks and G. Plewig, pp. 263-281. Springer, Berlin.
9. Lovell W. W. and Sanders D. J. (1990) Screening test for phototoxins using solutions of simple biochemicals. Toxicology in Vitro 4, 318-320.
10. Miranda M. A. (1992) Phototoxicity of drugs. In Alternative In Vitro Models to Animal Experimentation in Pharmaco-toxicology. Edited by J. V. Castell, Vol. 239. Farmaindustria, Barcelona.
11. Moore D. E. and Chappuis P. P. (1988) A comparative study of the photochemistry of the non-steroidal anti-inflammatory drugs naproxen, benoxaprofen and indomethacin. Photochemistry and Photobiology 47, 173-180.
12. Moore D. E. and Mallesch J. L. (1991) Photochemical interaction between triamterene and hydrochlorothiazide. International Journal of Pharmacy 76, 187-190.
13. Oertel R., Richter K., Dobrev K., Berndt A. and Gramatté T. H. (1994) Eine empfindliche HPLC-Methode zur bestimmung von Triamterenen im Serum. Pharmazie 49, 700-702.
14. Valenzeno D. P. and Trank J. W. (1985) Measurement of cell lysis by light scattering. Photochemistry and Photobiology 42, 335-339.
15. Vargas F., Rivas C., Machado R. and Miranda M. A. (1991) Photodegradation of nalidixic and tiaprofenic acids and of nifedipine in aerobic conditions. Photodermatology, Photoimmunology and Photomedicine 8, 218-221.
16. Vargas F. and Fuentes A. (1997) Evidence of formation and participation of singlet oxygen in the in vitro phototoxicity of the combined diuretic triamterene and hydrochlorothiazide. Pharmazie 52, 328-330.
17. Recknagel R. O. and Glenden E. A. (1984) Oxygen radicals in biological systems. In Methods in Enzymology. Edited by L. Packer, Vol. 105, p. 331. Academic Press, New York.
18. White I. R. (1983) Photopatch test in a hydrochlorothiazide drug eruption. Contact Dermatitis 9, 237.