Thymosin fraction 5 inhibits the proliferation of the rat neuroendocrine MMQ pituitary adenoma and C6 glioma cell lines in vitro

Endocrinology

Volumn 139, Issue 4, 1998, Pages 2155-2162

  Spangelo, Bryan L ^a   Farrimond, Derald D ^a   Thapa, Mahesh ^a   Bulathsinghala, Charles M ^a   Bowman, Kay Lynn ^a   Sareh, Alaleh ^a   Hughes Jr , Francis M ^b   Goldstein, Allan L ^c   Badamchian, Mahnaz ^c  

^a UNIVERSITY OF NEVADA   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THYMOSIN ALPHA1; THYMOSIN BETA4; THYMOSIN FRACTION 5;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GLIOMA CELL; HYPOPHYSIS ADENOMA; NEUROENDOCRINE TUMOR; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0031790551     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.139.4.5935     Document Type: Article

References (35)

1. Spangelo BL, Gorospe WC 1995 Role of the cytokines in the neuroendocrine-immune system axis. Front Neuroendocrinol 16:1-22
2. Spangelo BL 1995 The thymic-endocrine connection. J Endocrinol 147:5-10
3. Spangelo BL, Judd AM, Call GB, Zumwalt J, Gorospe WC 1995 Role of the cytokines in the hypothalamic-pituitary-adrenal and gonadal axes. Neuroimmunomodulation 2:299-312
4. McGillis JP, Hall NR, Vahouny GV, Goldstein AL 1985 Thymosin fraction 5 causes increased serum corticosterone in rodents in vivo. J Immunol 134:3952-3955
5. Healy DL, Hodgen GD, Schulte HM, Chrousos GP, Loriaux DL, Hall NR, Goldstein AL 1983 The thymus-adrenal connection: thymosin has corticotropin-releasing activity in primates. Science 222:1353-1355
6. Spinedi E, Hadid R, Daneva T, Gaillard RC 1992 Cytokines stimulate the CRH but not the vasopressin neuronal system: evidence for a median eminence site of interleukin-6 action. Neuroendocrinology 56:46-53
7. Goya RG, Castro MG, Hannah MJ, Sosa YE, Lowry PJ 1993 Thymosin peptides stimulate corticotropin release by a calcium-dependent mechanism. Neuroendocrinology 57:230-235
8. Milenkovic L, McCann SM 1992 Effects of thymosin alpha-1 on pituitary hormone release. Neuroendocrinology 55:14-19
9. 1 on hypothalamic hormone release. Neuroendocrinology 56:674-679
10. Spangelo BL, Judd AM, Ross PC, Login IS, Jarvis WD, Badamchian M, Goldstein AL, MacLeod RM 1987 Thymosin fraction 5 stimulates prolactin and growth hormone release from anterior pituitary cells in vitro. Endocrinology 121:2035-2043
11. Badamchian M, Spangelo BL, Damavandy T, MacLeod RM, Goldstein AL 1991 Complete amino acid sequence analysis of a peptide isolated from the thymus that enhances release of growth hormone and prolactin. Endocrinology 128:1580-1588
12. Badamchian M, Wang S-S, Spangelo BL, Damavandy T, Goldstein AL 1990 Chemical and biological characterization of MB-35: a thymic-derived peptide that stimulates the release of growth hormone and prolactin from rat anterior pituitary cells. Prog NeuroEndocrinImmunol 3:258-265
13. Arzt E, Buric R, Stelzer G, Stalla J, Sauer J, Renner U, Stalla GK 1993 Interleukin involvement in anterior pituitary cell growth regulation: effects of IL-2 and IL-6. Endocrinology 132:459-467
14. Sawada T, Koike K, Kanda Y, Ikegami H, Jikihara H, Maeda T, Osako Y, Hirota K, Miyake A 1995 Interleukin-6 stimulates cell proliferation of rat pituitary clonal cell lines in vitro. J Endocrinol Invest 18:83-90
15. Renner U, Newton CJ, Pagotto U, Sauer J, Arzt E, Stalla GK 1995 Involvement of interleukin-1 and interleukin-1 receptor antagonist in rat pituitary cell growth regulation. Endocrinology 136:3186-3193
16. Judd AM, Login IS, Kovaks K, Ross PC, Spangelo BL, Jarvis WD, MacLeod RM 1988 Characterization of the MMQ cell, a prolactin-secreting clonal cell line that is responsive to dopamine. Endocrinology 123:2341-2350
17. Benda P, Lightbody J, Sato G, Levine L, Sweet L 1977 Differentiated rat glial cell strain in tissue culture. Science 161:370-371
18. Mosmann T 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63
19. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ 1951 Protein measurement with the folin phenol reagent. J Biol Chem 193:265-275
20. Spangelo BL, Hall NR, Goldstein AL 1987 Biology and chemistry of thymosin peptides: modulators of immunity and neuroendocrine circuits. Ann NY Acad Sci 496:196-204
21. Attia WY, Badamchian M, Goldstein AL, Spangelo BL 1993 Thymosin stimulates interleukin-6 production from rat spleen cells in vitro, Immunopharmacology 26:171-179
22. Hadden EM, Malec P, Sosa M, Hadden JW 1992 Mixed interleukins and thymosin fraction V synergistically induce T lymphocyte development in hydrocortisone-treated aged mice. Int J Immunopharmacol 14:345-352
23. Ikemoto S, Kamizuru M, Hayahara N, Okamoto S, Wada S, Kishimoto T, Maekawa M 1992 Thymus lymphocytes in uraemic rats and the effect of thymosin fraction 5 in vivo. Clin Exp Immunol 87:220-223
24. 1 and α/β-interferon on NK activity in tumor bearing mice. Int J Immunopharmacol 11:443-450
25. 1 potentiates the anti-tumor activity of interleukin-2 with cyclophosphamide in the treatment of the Lewis lung carcinoma in mice. Int J Cancer 50:493-499
26. Kouttab NM, Goldstein AL, Lu M, Lu L, Campbell B, Maizel AL 1988 Production of human B and T cell growth factors is enhanced by thymic hormones. Immunopharmacology 16:97-105
27. Ganguli S, Hu L, Menke P, Collier RJ, Gertler A 1996 Nuclear accumulation of multiple protein kinases during prolactin-induced proliferation of Nb2 rat lymphoma cells. J Cell Physiol 167:251-260
28. Caron-Leslie L-AM, Evans RB, Cidlowski JA 1994 Bcl-2 inhibits glucocorticoid-induced apoptosis but only partially blocks calcium ionophore or cycloheximide-regulated apoptosis in S49 cells. FASEB J 8:639-645
29. Hall AK 1995 Thymosin beta-10 accelerates apoptosis. Cell Mol Biol Res 41:167-180
30. 1 down-regulates the growth of human non-small cell lung cancer cells in vitro and in vivo. Cancer Res 53:5214-5218
31. Plotkin SR, Banks WA, Kastin AJ 1996 Comparison of saturable transport and extracellular pathways in the passage of interleukin-1α across the blood-brain barrier. J Neuroimmunol 67:41-47
32. Gutierrez EG, Banks WA, Kastin AJ 1993 Murine tumor necrosis factor is transported from blood to brain in the mouse. J Neuroimmunol 47:169-176
33. Alvarez CV, Zalvide JB, Cancio E, Dieguez C, Regueiro BJ, Vega FV, Dominguez F 1993 Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells. Neuroendocrinology 57:1048-1056
34. Monier JC, Auger C, Corvee N, Stahli C, Fabien N 1988 Immunoreactivity of aqueous extracts of rat and mouse tissue with anti-thymosin alpha 1, antibovine thymopoietin and anti-thymulin antibodies. Thymus 11:173-183
35. 1-like peptides: localization and biochemical characterization in the rat brain and pituitary gland. Peptides 4:463-467