Identical twin marrow transplantation for venous thrombosis in paroxysmal nocturnal hemoglobinuria; Long-term complete remission as assessed by flow cytometry

Bone Marrow Transplantation

Volumn 22, Issue 7, 1998, Pages 717-721

  Doukas, M A ^a   Fleming, D ^b   Jennings, D ^c  

^a LEXINGTON VA MEDICAL CENTER   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

Flow cytometry; Marrow transplantation; Paroxysmal nocturnal hemoglobinuria

Indexed keywords

CD59 ANTIGEN;

ADULT; ARTICLE; BONE MARROW TRANSPLANTATION; CASE REPORT; CONTROLLED STUDY; DEEP VEIN THROMBOSIS; FEMALE; FLOW CYTOMETRY; FOLLOW UP; HISTOCOMPATIBILITY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MONOZYGOTIC TWINS; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; REMISSION;

EID: 0031790416     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701345     Document Type: Article

References (19)

1. Crosby W. Paroxysmal nocturnal hemoglobinuria: a classic description by Paul Strubing in 1882, and a bibliography of the disease. Blood 1951; 6: 270-284.
2. Hillmen P, Lewis SM, Bessler M et al. Natural history of paroxysmal nocturnal hemoglobinuria. New Engl J Med 1995; 333: 1253-1258.
3. Rosse W. Paroxysmal nocturnal hemoglobinuria: present status and future prospects. West J Med 1980; 132: 219-228.
4. Yeh ETH, Rosse WF. Paroxysmal nocturnal hemoglobinuria and the glycosylphosphatidylinositol anchor. J Clin Invest 1994; 93: 2305-2310.
5. Takeda J, Miyata T, Kawagoe K et al. Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 1993; 73: 703-711.
6. Peytremann R, Rhodes R, Hartmann R. Thrombosis in paroxysmal nocturnal hemoglobinuria (PNH) with particular reference to progressive, diffuse hepatic venous thrombosis. Ser Haematol 1972; 5: 115-136.
7. Doukas MA, DiLorenso PE, Mohler DN. Intestinal infarction caused by paroxysmal nocturnal hemoglobinuria. Am J Hematol 1983; 16: 673-675.
8. Crosby W. Paroxysmal nocturnal hemoglobinuria: relation of the clinical manifestations to underlying pathogenic mechanisms. Blood 1953; 8: 769-812.
9. Dacie JV, Lewis SM. Paroxysmal nocturnal hemoglobinuria, clinical manifestations, hematology and nature of the disease. Ser Haematol 1972; 5: 3-23.
10. Kawahara K, Witherspoon RP, Storb R. Marrow transplantation of paroxysmal nocturnal hemoglobinuria. Am J Hematol 1992; 39: 283-288.
11. Ostendorf T, Nischan C, Schubert J et al. Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria. Blood 1995; 84: 1640-1646.
12. Besler M, Mason P, Hillmen P, Luzzatto L. Somatic mutations and cellular selection in paroxysmal nocturnal hemoglobinuria. Lancet 1994; 343: 951-953.
13. Nafa K, Mason PH, Hillmen P et al. Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type. Blood 1995; 86: 4650-4655.
14. Pramoonjago P, Wanachiwanawin W, Chinprasertsak S et al. Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria. Blood 1995; 86: 1736-1739.
15. Wiedmer T, Hall SE, Ortel TL et al. Complement-induced vesiculation and exposure of membrane prothrombinase sites in platelets of paroxysmal nocturnal hemoglobinuria. Blood 1993; 82: 1192-1196.
16. Ploug M, Plesner T, Ronne E et al. The receptor for urokinasetype plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria. Blood 1992; 79: 1447-1455.
17. Ware RE, Rosse WF, Hall SE. Immunophenotypic analysis of reticulocytes in paroxysmal nocturnal hemoglobinuria. Blood 1995; 86: 1586-1589.
18. Perez-Oteyza J, Roldan E, Brieva JA et al. Expression of phosphatidylinositol anchored membrane proteins in paroxysmal nocturnal hemoglobinuria after bone marrow transplantation. Bone Marrow Transplant 1992; 10: 297-299.
19. Endo M, Beatty PG, Vreeke TM et al. Syngeneic bone marrow transplantation without conditioning in a patient with paroxysmal nocturnal hemoglobinuria: in vivo evidence that the mutant stem cells have a survival advantage. Blood 1996; 88: 742-750.