A targeted κ immunoglobulin gene containing a deletion of the nuclear matrix association region exhibits spontaneous hyper-recombination in pre-B cells

Molecular Immunology

Volumn 35, Issue 10, 1998, Pages 609-620

  Hale, Michael A ^a   Garrard, William T ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

immunoglobulin gene; Gene rearrangement; MAR; V and J region usage

Indexed keywords

IMMUNOGLOBULIN KAPPA CHAIN;

ARTICLE; B LYMPHOCYTE ACTIVATION; CELL NUCLEUS MATRIX; CHROMATIN STRUCTURE; DEMETHYLATION; DNA METHYLATION; ENHANCER REGION; GENE DELETION; GENE LOCUS; GENE MUTATION; GENE REARRANGEMENT; GENE TARGETING; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; IMMUNOGLOBULIN GENE; INTRON; NONHUMAN; PRIORITY JOURNAL;

ALLELES; ANIMALS; B-LYMPHOCYTES; BINDING SITES; DNA; DNA NUCLEOTIDYLTRANSFERASES; ENHANCER ELEMENTS (GENETICS); GENE REARRANGEMENT, B-LYMPHOCYTE, LIGHT CHAIN; GENE TARGETING; GENES, IMMUNOGLOBULIN; HEMATOPOIETIC STEM CELLS; IMMUNOGLOBULIN J-CHAINS; IMMUNOGLOBULIN KAPPA-CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; NUCLEAR MATRIX; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; VDJ RECOMBINASES;

EID: 0031790033     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0161-5890(98)00060-1     Document Type: Article

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