Anticoagulant activity in non-immunoglobulin fraction from plasma of patients with antiphospholipid syndrome

Seminars in Thrombosis and Hemostasis

Volumn 24, Issue 5, 1998, Pages 473-477

  Sugimura, Motoi ^a   Su, Fan ^a   Kanayama, Naohiro ^a   Kobayashi, Hiroshi ^a   Kobayashi, Takao ^a   Terao, Toshihiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Anticoagulant; Antiphospholipid syndrome (APS); IgG; Lupus anticoagulant (LA); Thrombin generation

Indexed keywords

BETA2 GLYCOPROTEIN 1; IMMUNOGLOBULIN G; LUPUS ANTICOAGULANT; PROTEIN KINASE C;

ANTICOAGULATION; ANTIPHOSPHOLIPID SYNDROME; BLOOD CLOTTING; CONFERENCE PAPER; HUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTHROMBIN TIME; SERODIAGNOSIS;

EID: 0031789425     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-996042     Document Type: Conference Paper

References (21)

1. Santoro SA. Antiphospholipid antibodies and thrombotic predisposition: Underlying pathogenic mechanisms. Blood 1994;83: 2389-2391
2. Carreras LO, Machin SJ, Deman R, et al. Arterial thrombosis, intrauterine death, and lupus anticoagulant: Detection of immunoglobulin interfering with prostacyclin formation. Lancet 1981;1:244-246
3. Freyssinet JM, Cazenava JP. Lupus-like anticoagulants-modulation of the protein C pathway and thrombosis. Thromb Haemostas 1987;58:679-681
4. Vogt E, Ng AK, Rote NS. A model for the antiphospholipid antibody syndrome: Monoclonal antiphosphatidylserine antibody induces intrauterine growth restriction in mice. Am J Obstet Gynecol 1996;174:700-707
5. Exner T, Triplett DA, Taberner D, Machin SJ. Guidelines for testing and revised criteria for lupus anticoagulants. SSC Subcommittee for the standardization of lupus anticoagulants. Thromb Haemostas 1991;65:320-322
6. Thiagarajan P, Shapiro SS, Mardeza LDM. Monoclonal immunoglobulin Mλ coagulation inhibitor with phospholipid specificity. J Clin Invest 1980;66:397-405
7. Rao LVM, Hoang AD, Rapaport SI. Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid. Blood 1996;88:4173-4182
8. Bevers EM, Galli M, Barburi T, Comfurius P, Zwaal RFA. Lupus anticoagulant IgG's (LA) are not directed to phospholipids only, but to a complex of lipid-bound human prothrombin. Thromb Haemostas 1991;66:629-632
9. Permpikul P, Rao LVM, Rapaport SI. Functional and binding studies of the role of prothrombin and β2-glycoprotein I in the expression of lupus anticoagulant activity. Blood 1994;83:2878-2892
10. Branch DW. Thoughts on the mechanism of pregnancy loss associated with the antiphospholipid syndrome. Lupus 1994;3: 275-280
11. Alving BM, Baldwin PE, Richards RL, Jackson BJ. The dilute phospholipid aPTT: A sensitive assay for verification of lupus anticoagulants. Thromb Haemostas 1985;54:709-712
12. Thiagarajan P, Pengo V, Shapiro SS. The use of the dilute Russell viper venom time for the diagnosis of lupus anticoagulants. Blood 1986;68:869-874
13. Liu HW, Wong KL, Lin CK, Wong WS, Tse PWT, Chan GTC. The reappraisal of dilute tissue thromboplastin inhibition test in the diagnosis of lupus anticoagulant. Br J Haematol 1989; 72:229-234
14. Triplett DA, Brandt JT, Kaczor D, Schaeffer J. Laboratory diagnosis of lupus inhibitor: A comparison of the tissue thromboplastin inhibition procedure with a new platelet neutralization procedure. Am J Clin Pathol 1983;79:678-682
15. Kaburaki J, Kuwana M, Yamamoto M, Kawai S, Matsuura E, Ikeda Y. Disease distribution of β2-glycoprotein I-dependent anticardiolipin antibodies in rheumatic diseases. Lupus 1995;4:S27-S31
16. Peng Z, Simons, FER, Becker AB. Differential binding properties of protein A and protein G for dog immunoglobulins. J Immunol Methods 1991;145:259-262
17. Sugimura M, Donato R, Kakkar VV, Scully MF. Annexin V as a probe of the contribution of anionic phospholipids to the procoagulant activity of tumour cell surfaces. Blood Coag Fibrinolysis 1994;5:365-373
18. Rosing J, Tans G, Govers-Reimslag WP, Zwaal RFA, Hemker HC. The role of phospholipid and factor Va in the prothrombinase complex. J Biol Chem 1980;255:274-283
19. Harris EN, Gharavi AE, Hughes GRV. Anti-phospholipid antibodies. Clin Rheum Dis 1985;11:591-609
20. Funakoshi T, Heimark RL, Hendrickson LE, MacMullen BA, Fujikawa K. Human placental anticoagulant protein: Isolation and characterization. Biochemistry 1987;26:5572-5578
21. Galli M, Bevers EM, Comfurius P, Barbui T, Zwaal RFA. Effect of antiphospholipid antibodies on procoagulant activity of activated platelets and platelet-derived microvesicles. Br J Haematol 1993;83:466-472