메뉴 건너뛰기




Volumn 9, Issue 8, 1998, Pages 689-696

Pharmacokinetics of recombinant human interferon-α2a combined with 5-fluorouracil in patients with advanced colorectal carcinoma

Author keywords

5 Fluorouracil; Colon carcinoma; Colorectal carcinoma; Interferon; Recombinant human interferon 2a

Indexed keywords

ALPHA2A INTERFERON; ANTINEOPLASTIC AGENT; FLUOROURACIL;

EID: 0031788827     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-199809000-00004     Document Type: Article
Times cited : (3)

References (31)
  • 1
    • 0027194943 scopus 로고
    • Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer
    • Shimada Y, Yoshino M, Wakui A, et al. Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. J Clin Oncol 1993; 11: 909-13.
    • (1993) J Clin Oncol , vol.11 , pp. 909-913
    • Shimada, Y.1    Yoshino, M.2    Wakui, A.3
  • 2
    • 0030818926 scopus 로고    scopus 로고
    • Phase II trial of irinotecan in patients with metastatic colorectal carcinoma
    • Pitot HC, Wender DB, O'Connell MJ, et al. Phase II trial of irinotecan in patients with metastatic colorectal carcinoma. J Clin Oncol 1997; 15: 2910-9.
    • (1997) J Clin Oncol , vol.15 , pp. 2910-2919
    • Pitot, H.C.1    Wender, D.B.2    O'Connell, M.J.3
  • 3
    • 0012797224 scopus 로고    scopus 로고
    • Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines
    • Machover D, Diaz-Rubio E, de Gramont A, et al. Two consecutive phase II studies of oxaliplatin (L-OHP) for treatment of patients with advanced colorectal carcinoma who were resistant to previous treatment with fluoropyrimidines. Ann Oncol 1996; 7: 95-8.
    • (1996) Ann Oncol , vol.7 , pp. 95-98
    • Machover, D.1    Diaz-Rubio, E.2    De Gramont, A.3
  • 4
    • 0023874456 scopus 로고
    • A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma
    • Erlichman C, Fine S, Wong A, Elhakim T. A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma. J Clin Oncol 1988; 6: 469-75.
    • (1988) J Clin Oncol , vol.6 , pp. 469-475
    • Erlichman, C.1    Fine, S.2    Wong, A.3    Elhakim, T.4
  • 5
    • 0024347268 scopus 로고
    • Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma
    • Poon MA, O'Connell MJ, Moertel CG, et al. Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma. J Clin Oncol 1989; 7: 1407-17.
    • (1989) J Clin Oncol , vol.7 , pp. 1407-1417
    • Poon, M.A.1    O'Connell, M.J.2    Moertel, C.G.3
  • 6
    • 0025606259 scopus 로고
    • Phase II study of fluorouracil and recombinant interferon alfa-2a in previously untreated advanced colorectal carcinoma
    • Pazdur R, Ajani JA, Patt YZ, et al. Phase II study of fluorouracil and recombinant interferon alfa-2a in previously untreated advanced colorectal carcinoma. J Clin Oncol 1990; 8: 2027-31.
    • (1990) J Clin Oncol , vol.8 , pp. 2027-2031
    • Pazdur, R.1    Ajani, J.A.2    Patt, Y.Z.3
  • 7
    • 0025668632 scopus 로고
    • Interferon alpha-2a and 5-fluorouracil for advanced colorectal carcinoma
    • Kemeny N, Younes A, Seiter K, et al. Interferon alpha-2a and 5-fluorouracil for advanced colorectal carcinoma. Cancer 1990; 66: 2470-5.
    • (1990) Cancer , vol.66 , pp. 2470-2475
    • Kemeny, N.1    Younes, A.2    Seiter, K.3
  • 8
    • 0026733526 scopus 로고
    • Phase II trial of 5-fluorouracil and recombinant interferon alfa-2b in metastatic colorectal carcinoma
    • Weh HJ, Platz D, Braumann D, et al. Phase II trial of 5-fluorouracil and recombinant interferon alfa-2b in metastatic colorectal carcinoma. Eur J Cancer 1992; 28A: 1820-3.
    • (1992) Eur J Cancer , vol.28 A , pp. 1820-1823
    • Weh, H.J.1    Platz, D.2    Braumann, D.3
  • 9
    • 0026635713 scopus 로고
    • Treatment of advanced colorectal cancer with recombinant interferon alpha and fluorouracil: Activity in liver metastasis
    • Diaz-Rubio E, Jimeno J, Camps C, et al. Treatment of advanced colorectal cancer with recombinant interferon alpha and fluorouracil: activity in liver metastasis. Cancer Invest 1992; 10: 259-64.
    • (1992) Cancer Invest , vol.10 , pp. 259-264
    • Diaz-Rubio, E.1    Jimeno, J.2    Camps, C.3
  • 10
    • 0024834136 scopus 로고
    • Fluorouracil and recombinant alfa-2a-interferon: An active regimen against advanced colorectal carcinoma
    • Wadler S, Schwartz EL, Goldman M, et al. Fluorouracil and recombinant alfa-2a-interferon: an active regimen against advanced colorectal carcinoma. J Clin Oncol 1989; 7: 1769-75.
    • (1989) J Clin Oncol , vol.7 , pp. 1769-1775
    • Wadler, S.1    Schwartz, E.L.2    Goldman, M.3
  • 11
    • 0025945855 scopus 로고
    • Phase II trial of fluorouracil and recombinant interferon alfa-2a in patients with advanced colorectal carcinoma: An Eastern Cooperative Oncology Group study
    • Wadler S, Lembersky B, Atkins M, Kirkwood J, Petrelli N. Phase II trial of fluorouracil and recombinant interferon alfa-2a in patients with advanced colorectal carcinoma: an Eastern Cooperative Oncology Group study. J Clin Oncol 1991; 9: 1806-10.
    • (1991) J Clin Oncol , vol.9 , pp. 1806-1810
    • Wadler, S.1    Lembersky, B.2    Atkins, M.3    Kirkwood, J.4    Petrelli, N.5
  • 12
    • 2642621053 scopus 로고
    • Interferon-alpha increases 5-fluorouracil (5FU) plasma levels 64-fold within one hour: Results of a phase I study
    • abstr II6-31
    • Lindley C, Bernard S, Gavigan M, Kaluzny B, Meadows L. Interferon-alpha increases 5-fluorouracil (5FU) plasma levels 64-fold within one hour: results of a phase I study. J Interferon Cytokine Res 1990; 10: (suppl 1): S132 (abstr II6-31).
    • (1990) J Interferon Cytokine Res , vol.10 , Issue.1 SUPPL.
    • Lindley, C.1    Bernard, S.2    Gavigan, M.3    Kaluzny, B.4    Meadows, L.5
  • 13
    • 0025949491 scopus 로고
    • A pilot study of interferon alfa-2a in combination with fluorouracil plus high-dose leucovorin in metastatic gastrointestinal carcinoma
    • Grem JL, McAtee N, Murphy RF, et al. A pilot study of interferon alfa-2a in combination with fluorouracil plus high-dose leucovorin in metastatic gastrointestinal carcinoma. J Clin Oncol 1991; 9: 1811-20.
    • (1991) J Clin Oncol , vol.9 , pp. 1811-1820
    • Grem, J.L.1    McAtee, N.2    Murphy, R.F.3
  • 14
    • 0025823831 scopus 로고
    • Pharmacokinetic aspects of the combination of interferon α2b and folinic acid with fluorouracil
    • Czejka MJ, Jager W, Schuller J, Fogl U, Schernthaner G. Pharmacokinetic aspects of the combination of interferon (α2b and folinic acid with fluorouracil. Arzneim-Forsch 1991; 41: 860-3.
    • (1991) Arzneim-Forsch , vol.41 , pp. 860-863
    • Czejka, M.J.1    Jager, W.2    Schuller, J.3    Fogl, U.4    Schernthaner, G.5
  • 15
    • 15144344523 scopus 로고
    • Lack of pharmacokinetic interaction when interferon-α2a is added to a combination of 5-fluorouracil and folinic acid
    • abstr P124
    • Patel N, Joel SP, Seymour MT, Slevin ML, Wrigley PFM. Lack of pharmacokinetic interaction when interferon-α2a is added to a combination of 5-fluorouracil and folinic acid. BrJ Cancer 1992; 65 (suppl 16): 61 (abstr P124).
    • (1992) BrJ Cancer , vol.65 , Issue.16 SUPPL. , pp. 61
    • Patel, N.1    Joel, S.P.2    Seymour, M.T.3    Slevin, M.L.4    Wrigley, P.F.M.5
  • 16
    • 0027267811 scopus 로고
    • Phase I trial of low-dose, prolonged continuous infusion fluorouracil plus interferon-alfa: Evidence for enhanced fluorouracil toxicity without pharmacokinetic perturbation
    • Sparano JA, Wadler S, Diasio RB, et al. Phase I trial of low-dose, prolonged continuous infusion fluorouracil plus interferon-alfa: evidence for enhanced fluorouracil toxicity without pharmacokinetic perturbation. J Clin Oncol 1993; 11: 1609-17.
    • (1993) J Clin Oncol , vol.11 , pp. 1609-1617
    • Sparano, J.A.1    Wadler, S.2    Diasio, R.B.3
  • 17
    • 0027403409 scopus 로고
    • Phase I and plasma pharmacokinetic study of infusional fluorouracil combined with recombinant interferon alfa-2b in patients with advanced cancer
    • Danhauser LL, Freimann JH, Gilchrist TL, et al. Phase I and plasma pharmacokinetic study of infusional fluorouracil combined with recombinant interferon alfa-2b in patients with advanced cancer. J Clin Oncol 1993; 11: 751-61.
    • (1993) J Clin Oncol , vol.11 , pp. 751-761
    • Danhauser, L.L.1    Freimann, J.H.2    Gilchrist, T.L.3
  • 18
    • 0028826705 scopus 로고
    • Pharmacokinetic interaction of 5-fluorouracil and interferon alpha-2b with or without folinic acid
    • Schuller J, Czejka M. Pharmacokinetic interaction of 5-fluorouracil and interferon alpha-2b with or without folinic acid. Med Oncol 1995; 12: 47-53.
    • (1995) Med Oncol , vol.12 , pp. 47-53
    • Schuller, J.1    Czejka, M.2
  • 19
    • 0019740867 scopus 로고
    • Purification of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies
    • Staehelin T, Hobbs DS, Kung H-F, Pestka S. Purification of recombinant human leukocyte interferon (IFLrA) with monoclonal antibodies. Methods Enzymol 1981; 78: 505-12.
    • (1981) Methods Enzymol , vol.78 , pp. 505-512
    • Staehelin, T.1    Hobbs, D.S.2    Kung, H.-F.3    Pestka, S.4
  • 20
    • 0026033464 scopus 로고
    • The analysis of 5-fluorouracil in human plasma by gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS) with stable isotope dilution
    • Bates CD, Watson DG, Willmott N, Logan H, Goldberg J. The analysis of 5-fluorouracil in human plasma by gas chromatography-negative ion chemical ionization mass spectrometry (GC-NICIMS) with stable isotope dilution. J Pharm Biomed Anal 1991; 9: 19-21.
    • (1991) J Pharm Biomed Anal , vol.9 , pp. 19-21
    • Bates, C.D.1    Watson, D.G.2    Willmott, N.3    Logan, H.4    Goldberg, J.5
  • 21
    • 0026004676 scopus 로고
    • Clinical trials of fluorouracil with alpha-interferon in advanced colorectal carcinoma
    • Pazdur R, Bready B, Moore DF. Clinical trials of fluorouracil with alpha-interferon in advanced colorectal carcinoma. Semin Oncol 1991; 18: 67-70.
    • (1991) Semin Oncol , vol.18 , pp. 67-70
    • Pazdur, R.1    Bready, B.2    Moore, D.F.3
  • 22
    • 0027395849 scopus 로고
    • Phase II evaluation of recombinant alpha-2a-interferon and continuous infusion fluorouracil and continuous infusion fluorouracil in previously untreated metastatic colorectal adenocarcinoma
    • Pazdur R, Ajani JA, Patt YZ, Gomez J, Bready B, Levin B. Phase II evaluation of recombinant alpha-2a-interferon and continuous infusion fluorouracil and continuous infusion fluorouracil in previously untreated metastatic colorectal adenocarcinoma. Cancer 1993; 71: 1214-8.
    • (1993) Cancer , vol.71 , pp. 1214-1218
    • Pazdur, R.1    Ajani, J.A.2    Patt, Y.Z.3    Gomez, J.4    Bready, B.5    Levin, B.6
  • 23
    • 0025058867 scopus 로고
    • Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion
    • Harris BE, Song R, Soong S-J, Diasio RB. Relationship between dihydropyrimidine dehydrogenase activity and plasma 5-fluorouracil levels with evidence for circadian variation of enzyme activity and plasma drug levels in cancer patients receiving 5-fluorouracil by protracted continuous infusion. Cancer Res 1990; 50: 197-201.
    • (1990) Cancer Res , vol.50 , pp. 197-201
    • Harris, B.E.1    Song, R.2    Soong, S.-J.3    Diasio, R.B.4
  • 24
    • 0029131435 scopus 로고
    • Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer
    • Hill M, Norman A, Cunningham D, et al. Impact of protracted venous infusion fluorouracil with or without interferon alfa-2b on tumor response, survival, and quality of life in advanced colorectal cancer. J Clin Oncol 1995; 13: 2317-23.
    • (1995) J Clin Oncol , vol.13 , pp. 2317-2323
    • Hill, M.1    Norman, A.2    Cunningham, D.3
  • 25
    • 0029016021 scopus 로고
    • Royal Marsden phase III trial of fluorouracil with or without interferon alfa-2b in advanced colorectal cancer
    • Hill M, Norman A, Cunningham D, et al. Royal Marsden phase III trial of fluorouracil with or without interferon alfa-2b in advanced colorectal cancer. J Clin Oncol 1995; 13: 1297-302.
    • (1995) J Clin Oncol , vol.13 , pp. 1297-1302
    • Hill, M.1    Norman, A.2    Cunningham, D.3
  • 26
    • 10144247244 scopus 로고    scopus 로고
    • Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer
    • Greco FA, Figlin R, York M, et al. Phase III randomized study to compare interferon alfa-2a in combination with fluorouracil versus fluorouracil alone in patients with advanced colorectal cancer. J Clin Oncol 1996; 14: 2674-81.
    • (1996) J Clin Oncol , vol.14 , pp. 2674-2681
    • Greco, F.A.1    Figlin, R.2    York, M.3
  • 27
    • 0029743089 scopus 로고    scopus 로고
    • Fluorouracil and leucovorin with or without interferon alfa-2b in advanced colorectal cancer: Analysis of a prospective randomized phase III trial
    • Kosmidis PA, Tsavaris N, Skarlos D, et al. Fluorouracil and leucovorin with or without interferon alfa-2b in advanced colorectal cancer: analysis of a prospective randomized phase III trial. J Clin Oncol 1996; 14: 2682-7.
    • (1996) J Clin Oncol , vol.14 , pp. 2682-2687
    • Kosmidis, P.A.1    Tsavaris, N.2    Skarlos, D.3
  • 28
    • 0028956096 scopus 로고
    • Phase III randomized study of two fluorouracil combinations with either interferon alfa-2a or leucovorin for advanced colorectal cancer
    • The Corfu-A Study Group. Phase III randomized study of two fluorouracil combinations with either interferon alfa-2a or leucovorin for advanced colorectal cancer. J Clin Oncol 1995; 13: 921-8.
    • (1995) J Clin Oncol , vol.13 , pp. 921-928
  • 29
    • 0026501911 scopus 로고
    • A phase II trial of 5-fluorouracil and recombinant alpha-2a-interferon in previously untreated metastatic gastric carcinoma
    • Pazdur R, Ajani JA, Winn R, et al. A phase II trial of 5-fluorouracil and recombinant alpha-2a-interferon in previously untreated metastatic gastric carcinoma. Cancer 1992; 69: 878-82.
    • (1992) Cancer , vol.69 , pp. 878-882
    • Pazdur, R.1    Ajani, J.A.2    Winn, R.3
  • 30
    • 0026757016 scopus 로고
    • Phase II evaluation of fluorouracil and recombinant α-2a-interferon in previously untreated patients with pancreatic adenocarcinoma
    • Pazdur R, Ajani JA, Abbruzzese JL, et al. Phase II evaluation of fluorouracil and recombinant α-2a-interferon in previously untreated patients with pancreatic adenocarcinoma. Cancer 1992; 70: 2073-6.
    • (1992) Cancer , vol.70 , pp. 2073-2076
    • Pazdur, R.1    Ajani, J.A.2    Abbruzzese, J.L.3
  • 31
    • 0003328398 scopus 로고    scopus 로고
    • The relative efficacy of 5-FU + leucovorin (FU-LV) and 5-FU-LV + interferon alfa-2a (IFN) in patients with Dukes' B and C carcinoma of the colon: First report of NSABP C-05
    • abstr 981
    • Wolmark N, Bryant J, Hyams DM, et al. The relative efficacy of 5-FU + leucovorin (FU-LV) and 5-FU-LV + interferon alfa-2a (IFN) in patients with Dukes' B and C carcinoma of the colon: first report of NSABP C-05. Proc Am Soc Clin Oncol 1998; 17: 255a (abstr 981).
    • (1998) Proc Am Soc Clin Oncol , vol.17
    • Wolmark, N.1    Bryant, J.2    Hyams, D.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.