Use of an ultrasensitive recombinant cell bioassay to determine estrogen levels in girls with precocious puberty treated with a luteinizing hormone- releasing hormone agonist

Journal of Clinical Endocrinology and Metabolism

Volumn 83, Issue 7, 1998, Pages 2387-2389

  Klein, Karen Oerter ^a   Baron, Jeffrey ^b   Barnes, Kevin M ^b   Pescovitz, Ora Hirsch ^b,c   Cutler Jr , Gordon B ^b,d  

^a NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c INDIANA UNIVERSITY MEDICAL CENTER   (United States)

^d ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DESLORELIN; ESTRADIOL; FOLLITROPIN; GONADORELIN AGONIST; GONADOTROPIN; LUTEINIZING HORMONE;

ARTICLE; BIOASSAY; BONE AGE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ESTRADIOL BLOOD LEVEL; FEMALE; GROWTH RATE; HUMAN; PRECOCIOUS PUBERTY; PREPUBERTY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0031788538     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.83.7.4929     Document Type: Article

References (8)

1. Mansfield MJ, Beardsworth DE, Loughlin JS, et al. 1983 Long-term treatment of central precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone: effects on somatic growth and skeletal maturation. N Engl J Med. 309:1286-1290.
2. Styne DM, Harris DA, Egli CA, et al. 1985 Treatment of true precocious puberty with a potent luteinizing hormone-releasing factor agonist: effect on growth, sexual maturation, pelvic sonography, and the hypothalamic-pituitary-gonadal axis. J Clin Endocrinol Metab. 61:142-151.
3. Boepple PA, Mansfield MJ, Wierman ME, et al. 1986 Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty. Endocr Rev. 7:24-33.
4. Manasco PK, Pescovitz OH, Hill SC, et al. 1989 Six-year results of luteinizing hormone releasing hormone (LHRH) agonist treatment in children with LHRH-dependent precocious puberty. J Pediatr. 115:105-108.
5. Pescovitz OH, Barnes KM, Cutler Jr GB. 1991 Effect of Deslorelin dose in the treatment of central precocious puberty. J Clin Endocrinol Metab. 72:60-64.
6. Klein K Oerter, Baron J, Colli MJ, McDonnell DP, Cutler Jr GB. 1994 Estrogen levels in childhood determined by an ultra-sensitive recombinant cell bioassay J Clin invest. 94:2475-2480.
7. Comite F, Cutler Jr GB, Rivier J, Vale WW, Loriaux DL, Crowley WF. 1981 Short-term treatment of idiopathic precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone. N Engl J Med. 305:1546-1550.
8. Norjavaara E, Ankarberg C, Albertsson-Wikland K. 1996, Diurnal rhythm of 17β-estradiol secretion thoughout pubertal development in healthy girls: evaluation by a sensitive readioimmunoassay, J Clin Endocrinol Metab. 81:4095-4102.