Novel OXA-10-derived extended-spectrum β-lactamases selected in vivo or in vitro

Antimicrobial Agents and Chemotherapy

Volumn 42, Issue 12, 1998, Pages 3113-3116

  Mugnier, P ^a,c   Casin, I ^a,b   Bouthors, A T ^a   Collatz, E ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c UNIVERSITY OF KENT   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMPICILLIN; ANTIBIOTIC AGENT; AZTREONAM; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOTAXIME; CEFSULODIN; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; DNA FRAGMENT; GENTAMICIN; IMIPENEM; PENICILLIN DERIVATIVE; PIPERACILLIN PLUS TAZOBACTAM; TIMENTIN;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; DNA SEQUENCE; ESCHERICHIA COLI; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIN RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA;

EID: 0031787913     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.42.12.3113     Document Type: Article

References (36)

1. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). Current protocols in molecular biology. Greene Publishing Associates and Wiley Interscience, New York, N.Y.
2. Bradford, M. M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing a principle of protein-dye binding. Anal. Biochem. 72:248-254.
3. Bush, K., G. A. Jacoby, and A. A. Medeiros. 1995. A functional classification scheme for β-lactamases and its correlation with molecular structure. Antimicrob. Agents Chemother. 39:1211-1233.
4. Casin, I., F. Bordon, P. Bertin, A. Coutrot, I. Podglajen, R. Brasseur, and E. Collatz. 1998. Aminoglycoside 6′-N-acetyltransferase variants of the Ib type with altered substrate profiles in clinical isolates of Enterobacter cloacae and Citrobacter freundii. Antimicrob. Agents Chemother. 42:209-215.
5. Collis, C. M., and R. M. Hall. 1995. Expression of antibiotic resistance genes in the integrated cassettes of integrons. Antimicrob. Agents Chemother. 39: 155-162.
6. Couture, F., J. Lachapelle, and R. C. Levesque. 1992. Phytogeny of LCR-1 and OXA-5 with class A and class D β-lactamases. Mol. Microbiol. 6:1693-1705.
7. Danel, F., L. M. C. Hall, and D. M. Livermore. 1997. Laboratory mutants of OXA-10 β-lactamase giving ceftazidime resistance in Pseudomonas aeruginosa, abstr. no. C191. In Program and Abstracts of the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
8. Danel, F., L. M. C. Hall, D. Gur, and D. M. Livermore. 1995. OXA-14, another extended-spectrum variant of OXA-10 (PSE-2) β-lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 39:1881-1884.
9. Danel, F., L. M. C. Hall, D. Gur, and D. M. Livermore. 1997. OXA-15, an extended-spectrum variant of OXA-2 β-lactamase, isolated from a Pseudomonas aeruginosa strain. Antimicrob. Agents Chemother. 41:785-790.
10. Hall, L. M., D. M. Livermore, D. Gur, M. Akova, and H. E. Akalin. 1993. OXA-11, an extended spectrum variant of OXA-10 (PSE-2) β-lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 37:1637-1644.
11. Hall, R. M., and C. M. Collis. 1995. Mobile gene cassettes and integrons: capture and spread of genes by site-specific recombination. Mol. Microbiol. 15:593-600.
12. Hedges, R. W., N. Datta, P. Kontomichalou, and J. T. Smith. 1974. Molecular specificities of R factor-determined β-lactamase: correlation with plasmid compatibility. J. Bacteriol. 117:56-62.
13. Huovinen, P., S. Huovinen, and G. A. Jacoby. 1988. Sequence of PSE-2 β-lactamase. Antimicrob. Agents Chemother. 32:134-136.
14. Jacobs, C., L. J. Huang, E. Bartowsky, S. Normark, and J. T. Park. 1994. Bacterial cell wall recycling provides cytosolic muropeptides as effectors for β-lactamase induction. EMBO J. 13:1684-1694.
15. Kado, C. I., and S. T. Liu. 1981. Rapid procedure for detection and isolation of large and small plasmids. J. Bacteriol. 145:1365-1373.
16. Knox, J. R. 1995. Extended-spectrum and inhibitor-resistant TEM-type β-lactamases: mutations, specificity, and three-dimensional structure. Antimicrob. Agents Chemother. 39:2593-2601.
17. Lambert, T., M. C. Ploy, and P. Courvalin. 1994. A spontaneous point mutation in the aac(6′)-Ib′ gene results in altered substrate specificity of aminoglycoside 6′-N-acetyltransferase of a Pseudomonas fluorescens strain. FEMS Microbiol. Lett. 115:297-304.
18. Ledent, P., X. Raquet, B. Joris, J. van Beeumen, and J. M. Frère. 1993. A comparative study of class D β-lactamases. Biochem. J. 292:555-562.
19. Lévesque, C., S. Brassard, J. Lapointe, and P. H. Roy. 1994. Diversity and relative strength of tandem promoters for the antibiotic-resistance genes of several integrons. Gene 142:49-54.
20. Mugnier, P., I. Podglajen, F. W. Goldstein, and E. Collatz. 1998. Carbapenems as inhibitors of OXA-13, a novel, integron-encoded β-lactamase in Pseudomonas aeruginosa. Microbiology 144:1021-1031.
21. Mugnier, P., I. Podglajen, L. Gutmann, and E. Collatz. 1994. Cloning and nucleotide sequence analysis of two Pseudomonas aeruginosa genes encoding the novel OXA-type β-lactamase variants OXA-12 and OXA-13, susceptible to inhibition by imipenem, abstr. no. C98. In Program and Abstracts of the 34th Interscience Conference on Antimicrobial Agents and Chemotherapy. American Society for Microbiology, Washington, D.C.
22. Mugnier, P., P. Dubrous, I. Casin, G. Arlet, and E. Collatz. 1996. A TEM-derived extended-spectrum β-lactamase in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 40:2488-2493.
23. Nordmann, P., and T. Naas. 1994. Sequence analysis of PER-1 extended-spectrum β-lactamase from Pseudomonas aeruginosa and comparison with class A β-lactamases. Antimicrob. Agents Chemother. 38:104-114.
24. Philippen, L. N., T. Naas, A.-T. Bouthors, V. Barakett, and P. Nordmann. 1997. OXA-18, a class D clavulanic-acid inhibited extended spectrum β-lactamase from Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 41: 2188-2195.
25. Pridmore, R. D. 1987. New and versatile cloning vectors with kanamycin-resistance marker. Gene 56:309-312.
26. Raquet, X., J. Lamotte-Brasseur, E. Fonzé, S. Goussard, P. Courvalin, and J. M. Frère. 1994. TEM β-lactamase mutants hydrolysing third-generation cephalosporins. J. Mol. Biol. 244:625-639.
27. Rather, P. N., H. Munayyer, P. A. Mann, R. S. Hare, G. H. Miller, and K. J. Shaw. 1992. Genetic analysis of bacterial acetyltransferases: identification of amino acids determining the specificities of the aminoglycoside 6′-N-acetyl-transferase Ib and IIa proteins. J. Bacteriol. 174:3196-3203.
28. Robillard, N. J. 1990. Broad-host-range gyrase A gene probe. Antimicrob. Agents Chemother. 34:1889-1894.
29. Sanschagrin, F., F. Couture, and R. C. Levesque. 1995. Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D β-lactamases. Antimicrob. Agents Chemother. 39:887-893.
30. Schmidt, F. R. J., E. J. Nücken, and R. B. Henschke. 1989. Structure and function of hot spots providing signals for site-directed specific recombination and gene expression in Tn21 transposons. Mol. Microbiol. 3:1545-1555.
31. Scoulica, E., A. Aransay, and Y. Tselentis. 1995. Molecular characterization of the OXA-7 β-lactamase gene. Antimicrob. Agents Chemother. 39:1379-1382.
32. Seifert, S. H., M. So, and F. Heffron. 1986. Shuttle mutagenesis: a method of introducing transposons into transformable organisms, p. 128-134. In J. K. Setlow and A. Hollander (ed.), Genetic engineering, principles and methods, vol. 8. Plenum, New York, N.Y.
33. Stokes, H. W., and R. M. Hall. 1989. A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons. Mol. Microbiol. 3:1669-1683.
34. Strynadka, N. C. J., H. Adachi, S. E. Jensen, K. Johns, A. Sielecki, C. Betzel, K. Sutoh, and M. N. G. James. 1992. Molecular structure of the acyl-enzyme intermediate in β-lactam hydrolysis at 1.7 Å resolution. Nature (London) 359:700-705.
35. Takahashi, S., and Y. Nagano. 1984. Rapid procedure for isolation of plasmid DNA and application to epidemiological analysis. J. Clin. Microbiol. 20: 608-613.
36. Tran Van Nhieu, G., and E. Collatz. 1987. Primary structure of an amino-glycoside 6′-N-acetyltransferase, AAC(6′)-4, fused in vivo with the signal peptide of the Tn3-encoded β-lactamase. J. Bacteriol. 169:5708-5714.