Comparison of total and free phenytoin serum concentrations measured by high-performance liquid chromatography and standard TDx assay: Implications for the prediction of free phenytoin serum concentrations

Therapeutic Drug Monitoring

Volumn 20, Issue 6, 1998, Pages 619-623

  May, Theodor W ^a,c   Rambeck, Bernard ^a   Jürges, Uta ^b   Blankenhorn, Volker ^b   Jürgens, Uwe ^a  

^a Gesell F Epilepsieforschung eV ^*  (Germany)

^b Epilepsy Center Kork   (Germany)

^c Biochemisches Labor   (Germany)

Author keywords

Phenytoin; Prediction; Protein binding; Valproic acid

Indexed keywords

PHENYTOIN; VALPROIC ACID;

ANALYTICAL ERROR; ARTICLE; COMPARATIVE STUDY; DIAGNOSTIC ACCURACY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; REGRESSION ANALYSIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FLUORESCENCE POLARIZATION; HUMANS; MODELS, THEORETICAL; PHENYTOIN; PROTEIN BINDING; VALPROIC ACID;

EID: 0031786217     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-199812000-00006     Document Type: Article

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