Isolation of recombinant phage clones expressing mycobacterial T cell antigens by screening a recombinant DNA library with human CD4+ Th1 clones

FEMS Immunology and Medical Microbiology

Volumn 22, Issue 3, 1998, Pages 205-216

  Mustafa, Abu Salim ^a   Lundin, Knut E A ^b   Oftung, Fredrik ^c  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UNIVERSITY OF OSLO   (Norway)

^c NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

gt11 library; CD4+ Th1 clone; Mycobacterial antigen; Recombinant phage clone

Indexed keywords

BACTERIAL ANTIGEN; CD4 ANTIGEN; HLA DR ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; RECOMBINANT DNA; T LYMPHOCYTE ANTIGEN;

ARTICLE; BACTERIOPHAGE LAMBDA; CLONE; CYTOTOXICITY; DNA LIBRARY; ESCHERICHIA COLI; HELPER CELL; MYCOBACTERIUM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

ANTIGEN-PRESENTING CELLS; ANTIGENS, BACTERIAL; CD4-POSITIVE T-LYMPHOCYTES; CLONE CELLS; GENE LIBRARY; HUMANS; LYMPHOCYTE ACTIVATION; LYSOGENY; MYCOBACTERIOPHAGES; MYCOBACTERIUM; MYCOBACTERIUM LEPRAE; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TH1 CELLS;

EID: 0031785858     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(98)00090-X     Document Type: Article

References (35)

1. North, R.J. (1973) Importance of thymus derived lymphocytes in cell mediated immunity to infection. Cell. Immunol. 7, 166-176.
2. Kaufmann, S.H.E. (1996) The interplay between cytokines and T cells in immunity to intracellular bacteria. In: T-Cell Subsets and Cytokines Interplay in Infectious Diseases (Mustafa, A.S., Al-Attiyah, R.J., Nath, I. and Chugh, T.D., Eds.), pp. 169-180. Karger, Basel.
3. Tascon, R.E., Stavropoulos, E., Lukacs, K.V. and Colston, M.J. (1998) Protection against Mycobacterium tuberculosis infection by CD8+ T cells requires the production of gamma interferon. Infect. Immun. 66, 830-834.
4. Abou-Zeid, C., Filley, E., Steele, J. and Rook, G.A.W. (1987) A simple new method for using antigens separated by polyacrylamide gel electrophoresis to stimulate lymphocytes in vitro after converting bands cut from western blots into antigen-bearing particles. J. Immunol. Methods 98, 5-10.
5. Gulle, H., Schoel, B. and Kaufmann, S.H.E. (1990) Direct blotting with viable cells of protein mixtures separated by two dimensional gel electrophoresis. J. Immunol. Methods 133, 253-261.
6. Andersen, P. and Heron, I. (1993) Simultaneous electroelution of whole SDS-polyacrylamide gels for the direct cellular analysis of complex protein mixtures. J. Immunol. Methods 161, 29-39.
7. Mustafa, A.S., Gill, H.K., Nerland, A., Britton, W.J., Mehra, V., Bloom, B.R., Young, R.A. and Godal, T. (1986) Human T cell clones recognize a major M. leprae antigen expressed in E. coli. Nature 319, 63-66.
8. Oftung, F., Mustafa, A.S., Husson, R., Young, R.A. and Godal, T. (1987) Human T cell clones recognize two abundant Mycobacterium tuberculosis protein antigen expressed in Escherichia coli. J. Immunol. 138, 927-931.
9. Young, R.A., Bloom, B.R., Grosskinsky, C.M., Ivanyi, J., Thomas, D. and Davis, R.W. (1985) Detection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc. Natl. Acad. Sci. USA 82, 2583-2587.
10. Young, R.A., Mehra, V., Sweetser, D., Buchanon, T., Clark-Curtiss, J., Davis, R.W. and Bloom, B.R. (1985) Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae. Nature 316, 450-452.
11. Mustafa, A.S., Oftung, F., Gill, H.K. and Natvig, I. (1986) Characteristics of human T cell clones from BCG and killed M. leprae vaccinated subjects and tuberculosis patients. Lepr. Rev. 57, 123-130.
12. Mustafa, A.S. (1995) Isolation and characterization of the genes of pathogenic mycobacteria that express antigens for T cell reactivity. Nutrition 11, 653-655.
13. Mustafa, A.S. (1996) Recombinant mycobacterial antigens recognized by human T cells. In: T-Cell Subsets and Cytokines Interplay in Infectious Diseases (Mustafa, A.S., Al-Attiyah, R.J., Nath, I. and Chugh, T.D., Eds.), pp. 201-211. Karger, Basel.
14. Mustafa, A.S. and Oftung, F. (1997) Identification of mycobacterial recombinant antigens recognized by human T cells. Med. Principles Pract. 6, 57-65.
15. Oftung, F. and Lundin, K.E.A. (1998) Identification of mycobacterial hsp70 reactive human T cell clones discriminating between M. tuberculosis and M. leprae. FEMS Immunol. Med. Microbiol. 20, 145-151.
16. Mustafa, A.S., Lundin, K.E.A., Meloen, R.H., Shinnick, T.M., Coulson, A.C.W. and Oftung, F. (1996) HLA-DR4 restricted T cell epitopes from the mycobacterial 60 000 molecular weight heat shock protein (hsp 60) do not map to the sequence homology regions with the human hsp 60. Immunology 87, 421-427.
17. Mustafa, A.S., Deggerdal, A., Lundin, K.A., Meloen, R.M., Shinnick, T.M. and Oftung, F. (1994) An HLA-DRw53-restricted T-cell epitope from a novel Mycobacterium leprae protein antigen important to the human memory T-cell repertoire against M. leprae. Infect. Immun. 62, 5595-5602.
18. Oftung, F., Geluk, A., Lundin, K.E.A., Meloen, R.H., Thole, J.E.R., Mustafa, A.S. and Ottenhoff, T.H.M. (1994) Mapping of multiple class II-restricted T-cell epitopes of the mycobacterial 70-kilodalton heat shock protein. Infect. Immun. 62, 5411-5418.
19. Mustafa, A.S. and Qvigstad, E. (1989) HLA-DR restricted antigen induced proliferation and cytotoxicity mediated by CD4+ T cell clones from subjects vaccinated with killed M. leprae. Int. J. Lepr. 57, 1-11.
20. Oftung, F., Lundin, K.E.A., Geluk, A., Ottenhoff, T.H.M., Shinnick, T.M., Meloen, R. and Mustafa, A.S. (1997) Primary structure and MHC restriction of peptide defined T cell epitopes from recombinantly expressed mycobacterial protein antigens. Med. Principles Pract. 6, 66-73.
21. Mustafa, A.S. and Oftung, F. (1993) Long lasting T cell reactivity to Mycobacterium leprae antigens in human volunteers vaccinated with killed M. leprae. Vaccine 11, 1108-1112.
22. Mustafa, A.S. and Godal, T. (1983) In vitro induction of human suppressor T cells by mycobacterial antigens. BCG activated OKT4+ cells mediate suppression of antigen-induced T cell proliferation. Clin. Exp. Immunol. 52, 29-37.
23. Vartdal, F., Gaudernack, G., Funderud, S., Bratlie, A., Lea, T., Ugelstad, J. and Thorsby, E. (1986) HLA class I and II typing using cells positively selected from blood by immunomagnetic isolation-a fast and reliable technique. Tissue Antigens 28, 301-312.
24. Ronningen, K.S., Spurkland, A., Markussen, G., Iwe, T., Vartdal, F. and Thorsby, E. (1990) Distribution of HLA class II alleles among Norwegian Caucasians. Hum. Immunol. 29, 275-281.
25. Sharrock, C., Lundin, K.E.A., Zeir, K., Zeevi, A., Thomson, M., Eirmann, T., Hansen, J.A., Mickelson, E. and Flomenberg, N. (1989) T cell recognition of HLA class II molecules: DR4 and DQw3. In: Immunobiology of HLA, Vol. 1 (Dupont, B., Ed.), pp. 509-513. Springer Verlag, New York.
26. Mustafa, A.S., Kvalheim, G., Degre, M. and Godal, T. (1986) Mycobacterium bovis BCG induced human T cell clones from BCG vaccinated healthy subjects: Antigen specificity and lymphokine production. Infect. Immun. 53, 491-497.
27. Mustafa, A.S. and Godal, T. (1985) BCG induced suppressor T cells optimal conditions for in vitro induction and mode of action. Clin. Exp. Immunol. 62, 474-481.
28. Oftung, F., Shinnick, T.M., Mustafa, A.S., Lundin, K.E.A., Godal, T. and Nerland, A.H. (1990) Heterogeneity among human T cell clones recognizing an HLA-DR4,Dw4-restricted epitope from the 18 kDa antigen of Mycobacterium leprae defined by synthetic peptides. J. Immunol. 144, 1478-1483.
29. Mustafa, A.S. (1988) Identification of T-cell activating recombinant antigens shared among three candidate antileprosy vaccines, killed M. leprae, M. bovis BCG and Mycobacterium w. Int. J. Lepr. 50, 265-273.
30. + cytotoxic T cells from BCG vaccinated healthy subjects: relation between cytotoxicity and suppression in vitro. Clin. Exp. Immunol. 69, 255-262.
31. Mustafa, A.S., Lundin, K.E.A. and Oftung, F. (1993) Human T cells recognize mycobacterial heat shock proteins in the context of multiple HLA-DR molecules: studies with healthy subjects vaccinated with Mycobacterium bovis BCG and Mycobacterium leprae. Infect. Immun. 61, 5294-5301.
32. Oftung, F., Mustafa, A.S., Shinnick, T.M., Houghton, R.A., Kvalheim, G., Degre, M., Lundin, K.E.A. and Godal, T. (1988) Epitopes of the Mycobacterium tuberculosis 65 kilodalton protein antigen as recognized by human T cells. J. Immunol. 141, 2749-2754.
33. Mustafa, A.S. and Oftung, F. (1997) Identification of mycobacterial recombinant antigens recognized by human T cells. Med. Principles Pract. 6, 57-65.
34. Satish, M., Esser, R.E., Thole, J.E.R. and Clark-Curtiss, J.E. (1990) Identification and characterization of antigenic determinants of Mycobacterium leprae that react with antibodies in sera of leprosy patients. Infect. Immun. 58, 1327-1336.
35. Del Prete, G. and Romagnani, S. (1996) Human TH1 and TH2 cells: functional properties, regulation of development and role in disease. In: T-Cell Subsets and Cytokines Interplay in Infectious Diseases (Mustafa, A.S., Al-Attiyah, R.J., Nath, I. and Chugh, T.D., Eds.), pp. 18-26. Karger, Basel.