Synthesis of 3'-arylsulfonyl-4'- [(diethoxyphosphoryl)difluoromethyl]thymidine analogs

Synthesis

Volumn , Issue 10, 1998, Pages 1511-1518

  Arnone, Alberto ^a   Bravo, Pierfrancesco ^b   Frigerio, Massimo ^b   Viani, Fiorenza ^a   Zappalà, Carmela ^b  

^a CNR   (Italy)

^b POLITECNICO DI MILANO   (Italy)

Author keywords

(difluoromethyl)phosphonates; 4' (diethoxyphosphoryl)difluoromethyl thymidines; A ntiviral agents; Fluorinated nucleosides; Lactol formation

Indexed keywords

4' [(DIETHOXYPHOSPHORYL)DIFLUOROMETHYL]THYMIDINE; ALCOHOL DERIVATIVE; FLUOROACETIC ACID; KETONE DERIVATIVE; LITHIUM DERIVATIVE; METHYLPHOSPHONIC ACID; NUCLEOSIDE ANALOG; TETRAHYDROFURAN DERIVATIVE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL REACTION; CHIRALITY; CYCLIZATION; DRUG SYNTHESIS; FLUORINATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; STEREOCHEMISTRY;

EID: 0031785774     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1998-4501     Document Type: Article

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