Kindling: Separate vs. shared mechanisms in affective disorders and epilepsy

Neuropsychobiology

Volumn 38, Issue 3, 1998, Pages 167-180

  Weiss, Susan R B ^a   Post, Robert M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Amygdala; Anticonvulsant; Psychiatry; Review; Seizures; Tolerance

Indexed keywords

4 AMINOBUTYRIC ACID; ATROPINE; CARBAMAZEPINE; CLONAZEPAM; CLONIDINE; COCAINE; DIAZEPAM; DIZOCILPINE; GABAPENTIN; LAMOTRIGINE; LIDOCAINE; MESSENGER RNA; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; NEUROPEPTIDE Y; OPIATE; PHENYTOIN; PROTIRELIN; VALPROIC ACID;

AFFECTIVE NEUROSIS; AMYGDALOID NUCLEUS; CLINICAL TRIAL; CONFERENCE PAPER; DEPRESSION; DISEASE COURSE; DRUG CROSS TOLERANCE; ELECTROCONVULSIVE THERAPY; EPILEPSY; EXPERIMENTAL MODEL; GENE EXPRESSION; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; KINDLING; LONG TERM POTENTIATION; META ANALYSIS; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL;

AMYGDALA; ANIMALS; ANTICONVULSANTS; DEPRESSION; DISEASE PROGRESSION; DRUG RESISTANCE; DRUG TOLERANCE; EPILEPSY; HUMANS; KINDLING, NEUROLOGIC; MODELS, NEUROLOGICAL; MOOD DISORDERS; NEURAL INHIBITION; NEURONAL PLASTICITY;

EID: 0031785311     PISSN: 0302282X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000026533     Document Type: Conference Paper

References (87)

1. Goddard LS, McIntyre DC, Leech CK: A permanent change in brain function resulting from daily electrical stimulation. Exp Neurol 1969; 25:295-330.
2. Pinel JPJ, Rovner LI: Experimental epileptogenesis: Kindling-induced epilepsy in rats. Exp Neurol 1978;58:335 346.
3. Pinel J: Spontaneous kindled motor seizures in rats; in Wada J (ed): Kindling II. New York, Raven Press, 1981, pp 179 192.
4. Sakai S, Baba H, Sato M, Wada JA: Effect of DN-1417 on photosensitivity and cortically kindled seizure in senegalese baboons, papio papio. Epilepsia 1991;32:16 21.
5. Wada JA, Sato M, Corcoran ME: Persistent seizure susceptibility and recurrent spontaneous seizures in kindled cata. Epilepsia 1974;15:465.
6. Engel J: The syndrome of mesial temporal lobe epilepsy: A role for kindling; in Corcoran ME, Moshe SL (eds): Kindling V. New York, Plenum Press, 1998, pp 469-484.
7. McNamara JO, Russel RD, Rigsbee L, Bonhaus DW: Anticonvulsant and antiepileptogenic actions of MK-801 in the kindling and electroshock models. Neuropharmacology 1988;27: 563 568.
8. Loscher W, Fisher JE, Nau H, Honack D: Valproic acid in amygdala-kindled rats: Alterations in anticonvulsant efficacy, adverse effects and drug and metabolite levels in various brain regions during chronic treatment. J Pharmacol Exp Ther 1989;250:1067 1078.
9. Albertson TE, Joy RM, Stark LG: Carbamazepine: A pharmacological study in the kindling model of epilepsy. Neuropharmacology 1984; 23:1117-1124.
10. Goddard GV, Douglas RM: Does the engram of kindling model the engram of normal long term memory. Can J Neurol Sci 1975;2:385-398.
11. Racine R: Kindling: The first decade. Neurosurgery 1978;3:234-252.
12. Post RM, Putnam F, Uhde TW, Weiss SRB: ECT as an antieonvulsant: Implications for its mechanism of action in affective illness. Ann NY Acad Sci 1986;462:376 388.
13. Post RM, Weiss SRB: Mode of action of anticonvulsants in affective illness; in Lerer B, Gershon S (eds): New Directions in Affective Disorders. New York, Springer, 1990.
14. Post R, Weiss S: Kindling: Implications for the course of treatment of affective disorders; in Modigh K, Robak O, Vestergaard P (eds): Anticonvulsants in Psychiatry. Hampshire, UK, Wrightson Biomedical, 1994, pp 113-137.
15. Weiss SRB, Post RM: Caveats in the use of the kindling model of affective disorders. Toxicol Indust Hlth 1994;10:421-447.
16. Mayberg HS: Limbic-cortical dysregulation: A proposed model of depression. J Neuropsychiatry Clin Neurosci 1997:471-481.
17. Post RM, Altshuler LL, Ketter TA, Denicoff K, Weiss SR: Antiepileptic drugs in affective illness: Clinical and theoretical implications Adv Nurol 1991;55:239 277.
18. Post RM, Weiss SRB, Chang D-M, Ketter TA: Mechanisms of action of carbamazepine in seizure and affective disorders; in Joffe RT, Calabrese JR (eds): Anticonvulsants in Mood Disorders. New York, Marcel Dekker, 1994. pp 43-92.
19. Pinel JPJ: Effects of diazepam and diphenylhydantoin on elicited and spontaneous seizures in kindled rats: A double dissociation. Pharmacol Biochem Behav 1983;18:61-63.
20. Weiss SRB, Post RM: Carbamazepine and carbamazepine-10,11-epoxide inhibit amygdala-kindled seizures in the rat but do not block their development. Clin Neuropharmacol 1987; 10:272-279.
21. Weiss SRB, Post RM, Szele F, Woodward R, Nierenberg J: Chronic carbamazepine inhibits the development of local anesthetic seizures kindled by cocaine and lidocaine. Brain Res 1989;497:72-79.
22. Weiss SRB, Post RM, Costello M, Nutt DJ, Tandeciarz S: Carbamazepine retards the development of cocaine-kindled seizures but not sensitization to cocaine-induced hyperactivity. Neuropsychopharmacology 1990;3:273-281.
23. Post RM, Kopanda RT, Lee A: Progressive behavioral changes during chronic lidocaine administration: Relationship to kindling. Life Sci 1975;17:943-950.
24. Post RM: Lidocaine kindled limbic seizures: Behavioral implications; in Wada JA (ed): Kindling 2. New York, Raven Press, 1981, pp 149-160.
25. Weiss SRB, Post RM, Aigner TG: Carbamazepine in the treatment of cocaine-induced disorders; in Watson RR (ed): Drug and Alcohol Abuse Reviews: Treatment of Drug and Alcohol Abuse. Clifton, Humana Press, 1992.
26. Clark M, Post RM, Weiss SRB, Cain CJ, Nakajima T: Regional expression of c-fos mRNA in rat brain during the evolution of amygdala kindled seizures. Mol Brain Res 1991;11:55-64.
27. Namba H, Iwasa H, Kubota M, Hagihara Y, Yamaura A: Changes of hippocampal glucose utilization subsequent to amygdaloid-kindled generalized seizures. Epilepsia 1991;32:27-32.
28. Caldecott-Hazard S, Engel J Jr: Limbic postictal events: Anatomical substrates and opioid receptor involvement. Prog Neuropsychopharmacol Biol Psychiatry 1987;11:389-118.
29. Pinel JPJ, Rovner LI: Electrode placement and kindling-induced experimental epilepsy. Lxp Neurol 1978;58:335 346.
30. Pinel JPJ: Kindling-induced experimental epilepsy in rats: Cortical stimulation. Exp Neurol 1981;71:559 569.
31. Post RM: Central stimulants: Clinical and experimental evidence on tolerance and sensitization: in Israel Y, Glaser F, Kalant H, Pophain RE, Schmidt W, Smart R (eds): Research Advances in Alcohol and Drug Problems. New York, Plenum Press, 1981. pp 1 65.
32. Downs AW, Eddy NB: The effect of repeated doses of cocaine on the rat. J Pharmacol Exp Ther 1932;46:199.
33. Post RM, Weiss SRB, Pert A: Sensitization and kindling effects of chronic cocaine administration; in Lakoski JM, Galloway MP, White FJ (eds): Cocaine Pharmacology, Physiology, and Clinical Strategies. Boca Raton, CRC Press, 1991. pp 115 161.
34. King G, Joyner C, Lee T, Kuhn C, Ellinwood E Jr: Intermittent and continuous cocaine administration: Residual behavioral states during withdrawal. Pharmacol Biochem Behav 1992; 43:243 248.
35. King G, Joyner C, Ellinwood EJ: Withdrawal from continuous or intermittent cocaine: Behavioral responsivity to 5-HT1 receptor agonists. Pharmacol Biochem Behav 1993;45:577 587.
36. Gilman AG, Goodman LS, Rall TW, Murad F: Goodman and Gillman's The Pharmacological Basis of Therapeutics, ed 7. New York, Macmillan, 1985.
37. Weiss SRB, Post RM: Development and reversal of contingent inefficacy and tolerance to the anticonvulsant effects of carbamazepine. Epilepsia 1991;32:140 145.
38. Mana MJ, Kim CK, Pinel JPJ, Jones CH: Contingent tolerance to the anticonvulsant effects of carbamazepine. diazepam. and sodium valproate in kindled rats. Pharmucol Biochem Behav 1992;41:121-126.
39. Mana MJ, Pinel JPF, Kim CK: Contingent tolerance to diazepam's anticonvulsant effect on amygdaloid kindled seizures in the rat. Soc Neurosci Abstr 1986;12:1564(422.11).
40. Pinel JPJ, Mana MJ, Renfrey G: Contingent tolerance to the anticonvulsant effects of alcohol. Alcohol 1985;2:495-499.
41. Weiss SRB, Clark M, Rosen JB, Smith MA, Post RM: Contingent tolerance to the anticonvulsant effects of carbamazepine: Relationship to loss of endogenous adaptive mechanisms. Brain Res Rev 1995;20:305 325.
42. Rosen JB, Kim S-Y, Post RM: Differential regional and time course increases in thyrotropin-releasing hormone, neuropeptide Y and enkephalin mRNAs following an amygdala kindled seizure. Mol Brain Res 1994;27:71 80.
43. Sato M, Morimoto K: Anti-epileptic effects of TRH-T and DN-1417. Kurume Med J 1983;30: S57 S64.
44. Kubck MJ, Low WC, Sattin A, Morzorati SL, Meyerhoff JL, Larsen SH: Role of TRH in seizure modulation. Ann NY Acad Sci 1989;553: 286 303.
45. Wan R-Q, Noguera EC, Weiss SRB: Anticonvulsant effects of intra-hippocampal injection of TRH in amygdala kindled rats. NeuroReport 1998; in press.
46. A receptor system in kindled rats by autoradiographic and in situ hybridization techniques: Contingent tolerance to carbamazepine. Mol Brain Res 1994;26:309-319.
47. Rosen JB, Weiss SRB, Post RM: Contingent tolerance to carbamazepine: Alterations in TRH mRNA and TRH receptor binding in limbic structures. Brain Res 1994;651:252 260.
48. Weiss SRB, Lewis R, Sohn E, Berger A, Post RH: Cross tolerance between carbamazepine and valproate in an amygdala kindled seizure paradigm (abstract). Soc Neurosci 1991 (Abstracts).
49. Weiss SRB, Post RM, Sohn E, Berger A, Lewis R: Cross-tolerance between carbamazepine and valproate on amygdala-kindled seizures. Epilepsy Res 1993;16:37-44.
50. Post RM, Weiss SRB: The neurobiology of treatment-resistant mood disorders; in Bloom FE. Kupfer DJ (eds): Psychopharmacology: The Fourth Generation of Progress. New York, Raven, 1995, pp 1155 1170.
51. Post RM, Mikalauskas K: Lithium tolerance and discontinuation as pathways to refractoriness: in Birch NJ, Padgham C, Hughes MS (eds): Lithium in Medicine and Biology. Lancashire, Marius, 1993. pp 71 84.
52. Post RM, Weiss SRB: Endogenous biochemical abnormalities in affective illness: Therapeutic vs. pathogenic. Biol Psychiatry 1992;32:469 484.
53. Callahan AM, Frye MA, Marangell LB, George MS, Ketter TA, L'Herrou T, Post RM: Comparative antidepressant effects of intravenous and intrathecal thyrotropin-releasing hormone: Confounding effects of tolerance and implications for therapeutics. Biol Psychiatry 1997;41: 264-272.
54. Marangell LB, George MS, Callahan AM, Ketter TA, Pazzaglia PJ, L'Herrou TA, Leverich GS, Post RM: Effects of intrathecal thyrotropin-releasing hormone (protirelin) in refractory depressed patients. Arch Gen Psychiatry 1997;54: 214 222.
55. Banki CM, Bissette G, Arato M, Nemeroff CB: Elevation of immunoreactive CSF TRH in depressed patients. Am J Psychiatry 1988;145: 1526 1531.
56. Ogawa N, Mizuno S, Mori A, Nukina I, Ota Z, Yamamoto M: Potential anti-depressive effects of thyrotropin releasing hormone (TRH) and its analogues. Peptides 1984;5:743 746.
57. Metcalf G: Regulatory peptides as a source of new drugs: The clinical prospects for analogues of TRH which are resistant to metabolic degradation. Brain Res 1982;257:389-408.
58. Huey LY, Janowsky DS, Mandell AJ, Judd LL. Pendery M: Preliminary studies on the use of thyrotropin releasing hormone in manic states, depression, and the dysphoria of alcohol withdrawal. Psychopharmacol Bull 1975;11:24-27.
59. Prange AJJ, Lara PP, Wilson IC, Alltop LB, Breese GR: Effects of thyrotropin-releasing hormone in depression. Lancet 1972;ii:999 1002.
60. Malenka RC: Synaptic plasticity in the hippocampus: LTP and LTD. Cell 1994;78:535-538.
61. Bear MF, Malenka RC: Synaptic plasticity: LTP and LTD. Curr Opin Neurobiol 1994;4:389 399.
62. Christie BR, Kerr DS, Abraham WC: Flip side of synaptie plasticity: Long-term depression mechanisms in the hippocampus. Hippocampus 1994;4:127 135.
63. Linden DJ: Long-term synaptic depression in the mammalian brain. Neuron 1994;12:457 472.
64. O'Dell TJ, Kandel ER: Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases. Learning Memory 1994;1:129 139.
65. Bliss T, Collingridge GL: A synaptic model of memory: Long-term potentiation in the hippocampus. Nature 1993;361:31 39.
66. Bliss T, Lomo T: Long-lasting potnetiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path. J Physiol 1973;232:331 356.
67. Tsumoto T: Long-term potentiation and long-term depression in the neocortex. Prog Neurobiol 1992;39:209 228.
68. Racine RJ, Wilson DA, Gingell R, Sunderland D: Long-term potentiation in the interpositus and vestibular nuclei in the rat. Exp Brain Res 1986;63:158 162.
69. Teyler TJ, Discenna P: Long-term potentiation as a candidate mnemonic device. Brain Res 1984;319:15 28.
70. Cain D: Long-term potentiation and kindling: How similar are the mechanisms? Trends Neurosci 1989;12:6-10.
71. Cain DP: Kindling in genetically altered mice: Implications for the role of LTP in kindling: in Corcoran ML, Moshe SL (eds): Kindling V. New York, Plenum Press, 1998. pp 285 298.
72. Froc D, Trepel C, Racine R: Induction of neocortical depotentiation and long-term depression in the adult behaving rat. Soc Neurosci Abstr 1996;22:1504.
73. Bashir ZI, Collingridge GL: An investigation the depotentiation ot long-term potentiation in the Cal region of the hippocampus. Exp Brain Res 1994;100:437-443.
74. Weiss SRB, Li XL, Rosen JB, Li H, Heynen T, Post RM: Quenching: Inhibition of development and expression of amygdala kindled seizures with low frequency stimulation. NeuroReport 1995;4:2171 2176.
75. Weiss S, Li X-L, Rosen J, Li H, Heynen T, Noguera E, Sitcoske M, Wan R: Quenching vs. kindling: Persistent alterations in neural responsivity. Ahstr ACNP 1996:193.
76. George MS, Wassermann E.M, Williams WA, Callahan A, Ketter TA, Basser P, Halleti M, Post RM: Daily repetitive transcranial magnetic stimulation (rTMS) improves mood in depression. NeuroReport 1995;6:1853-1856.
77. George MS, Wassermann EM, Williams WA, Steppel J, Pascual-Leone A, Basser P, Halleti M, Post RM: Changes in mood and hormone levels after rapid-rate transcranial magnetic stimulation (rTMS) of the prefrontal cortex J Neuropsychiatry Clin Neurosci 1996;8:172 ISO.
78. Kirkcaldie MT, Pridmore SA, Pascual-Leone A: Transcranial magnetic stimulation as therapy for depression and other disorders. Aust N Z J Psychiatry 1997;31:264-272.
79. Pascual-Leone A, Rubio B, Pallardo F, Catala MD: Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression [see comments]. Lancet 1996;348:233-237.
80. Post R, Kimbrell T, Frye M, George M, McCann U, Little J, Dunn R, Li H, Weiss S: Implication of kindling and quenching for the possible frequency dependence of rTMS. CNS Spectrums 1997;2:45-61.
81. Baxter LR Jr, Schwartz JM, Phelps ME, Mazziotta JC, Guze BH, Selin CE, Gerner RH, Sumida RM: Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry 1989;46:243-250.
82. Kennedy SH, Javanmard M, Vaccarino FJ: A review of functional neuroimaging in mood disorders: Positron emission tomography and depression. Can J Psychiatry 1997;42:467-475.
83. Bench CJ, Friston KJ, Brown RG, Scott LC, Frackowiak RS, Dolan RJ: The anatomy of melancholia: Focal abnormalities of cerebral blood flow in major depression. Psychol Med 1992; 22:607-615.
84. Shin LM, McNally RJ, Kosslyn SM, Thompson WL. Rauch SL, Alpert NM, Metzger LJ, Lasko NB, Orr SP, Pitman PK: A positron emission tomographic study of symptom provocation in PTSD. Ann NY Acad Sci 1997;821:521-523.
85. Rauch SL, van der Kolk BA, Fisler RE, Alpert NM, Orr SP, Savage CR, Fischman AJ, Jenike MA, Pitman RK: A symptom provocation study of posttraumatic stress disorder using positron emission tomography and script-driven imagery. Arch Gen Psychiatry 1996;53:380-387.
86. McCann UD, Kimbrell TA, George MS, Danielson AL, Herscovitch P, Hallett M, Post RM: Repetitive transcranial magnetic stimulation for PTSD: Two case reports. Arch Gen Psychiatry 1998; in press.
87. Kimbrell TA, Dunn RT, Wasserman EM, George MS, Danielson AL, Benson BE, Herscovitch P, Post RM: Regional decreases in glucose metabolism with 1 Hz prefrontal transcranial magnetic stimulation (TMS): A new technique for tracing functional networks in the human brain (abstracts). Soc Neurosci 1997;23: 1576.