Dietary protein restriction alters glucose but not protein metabolism in non-insulin-dependent diabetes mellitus

Metabolism: Clinical and Experimental

Volumn 47, Issue 9, 1998, Pages 1145-1151

  Hoffer, L John ^a,b   Taveroff, Arlene ^a   Hamadeh, Mazen J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMINO ACID METABOLISM; ARTICLE; CATABOLISM; DIET RESTRICTION; DIETARY INTAKE; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; HUMAN; HUMAN EXPERIMENT; MALE; NITROGEN BALANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; NORMAL HUMAN; NUTRITIONAL REQUIREMENT; PRIORITY JOURNAL; PROTEIN INTAKE; PROTEIN METABOLISM;

EID: 0031784118     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0026-0495(98)90291-8     Document Type: Article

References (51)

1. Magnusson I, Rothman DL, Katz LD, et al: Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study. J Clin Invest 90:1323-1327, 1992
2. Consoli A: Role of liver in pathophysiology of NIDDM. Diabetes Care 15:430-441, 1992
3. Jenssen T, Nurjhan N, Consoli A, et al: Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans. J Clin Invest 86:489-497, 1990
4. Jahoor F, Peters EJ, Wolfe RR: The relationship between gluconeogenic substrate supply and glucose production in humans. Am J Physiol 258:E288-E296, 1990
5. Paquot N, Schneiter P, Jequier E, et al: Effects of ingested fructose and infused glucagon on endogenous glucose production in obese NIDDM patients, obese non-diabetic subjects, and healthy subjects. Diabetologia 39:580-586, 1996
6. Perriello G, Nurjhan N, Stumvoll M, et al: Regulation of gluconeogenesis by glutamine in normal postabsorptive humans. Am J Physiol 35:E437-E445, 1997
7. Dietze G, Wicklmayr M, Hepp KD, et al: On gluconeogenesis of human liver. Diabetologia 12:555-561, 1976
8. Khan MA, Gannon MC, Nuttall FQ: Glucose appearance rate following protein ingestion in normal subjects. J Am Coll Nutr 11:701-706, 1992
9. Rossetti L, Rothman DL, DeFronzo RA, et al: Effect of dietary protein on in vivo insulin action and liver glycogen repletion. Am J Physiol 257:E212-E219, 1989
10. Tappy L, Acheson K, Normand S, et al: Effects of infused amino acids on glucose production and utilization in healthy adult subjects. Am J Physiol 262:E826-E833, 1992
11. Ahmed M, Nuttall FQ, Gannon MC, et al: Plasma glucagon and α-amino acid nitrogen response to various diets in normal humans. Am J Clin Nutr 33:1917-1924, 1980
12. Boden G, Tappy L, Jadali F, et al: Role of glucagon in disposal of an amino acid load. Am J Physiol 259:E225-E232, 1990
13. Jungas RL, Halperin ML, Brosnan JT: Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans. Physiol Rev 72:419-448, 1992
14. Lariviere F, Chiasson J-L, Schiffrin A, et al: Effects of dietary protein restriction on glucose and insulin metabolism in normal and diabetic humans. Metabolism 43:462-467, 1993
15. Hoffer LJ, Taveroff A, Schiffrin A: Metabolic adaptation to protein restriction in insulin-dependent diabetes mellitus. Am J Physiol 272:E59-E67, 1997
16. El-Khoury AE, Fukagawa NK, Sanchez M, et al: Validation of the tracer-balance concept with reference to leucine: 24-h intravenous tracer studies with L-[1-13C]leucine and [15N-15N]urea. Am J Clin Nutr 59:1000-1011, 1994
17. El-Khoury AE, Fukagawa NK, Sanchez M, et al: The 24-h pattern and rate of leucine oxidation, with particular reference to tracer estimates of leucine requirements in healthy adults. Am J Clin Nutr 59:1012-1020, 1994
18. Clark HD, Hoffer LJ: Reappraisal of the resting metabolic rate of normal young men. Am J Clin Nutr 53:21-26, 1991
19. Kushner RF, Kunigk A, Alspaugh M, et al: Validation of bioelectrical-impedance analysis as a measurement of change in body composition in obesity. Am J Clin Nutr 52:19-23, 1990
20. Food and Agriculture Organization/World Health Organization/ UNU Expert Consultation: Energy and protein requirements. World Health Organ Tech Rep Ser 724, 1985
21. Wolfe RR, Allsop JR, Burke JF: Glucose metabolism in man: Responses to intravenous glucose infusion. Metabolism 28:210-220, 1979
22. Caballero B, Wurtman RJ: Differential effects of insulin resistance on leucine and glucose kinetics in obesity. Metabolism 40:51-58, 1991
23. 13C-labelled glucose by mass spectrometry: Applications to the study of gluconeogenesis in liver cells. Biomed Environ Mass Spectrom 18:1010-1015, 1989
24. Bier DM: Intrinsically difficult problems: The kinetics of body proteins and amino acids in man. Diabetes Metab Rev 5:111-132, 1989
25. Taveroff A, Hoffer LJ: Are leucine turnover measurements valid in the intravenously fed state? Metabolism 43:1338-1345, 1993
26. Schwenk WF, Berg PJ, Beaufrere B, et al: Use of t-butyldimethylsilylation in the gas chromatographic/mass spectrometric analysis of physiologic compounds found in plasma using electron-impact ionization. Anal Biochem 141:101-109, 1984
27. 13C]leucine. Am J Physiol 238:E473-E479, 1980
28. Munro HN, Fleck A: Analysis of tissues and body fluids for nitrogenous constituents, in Munro HN (ed): Mammalian Protein Metabolism, vol 3. New York, NY, Academic, 1969, pp 424-525
29. Maroni BJ, Steinman TI, Mitch WE: A method for estimating nitrogen intake of patients with chronic renal failure. Kidney Int 27:58-65, 1985
30. Hoffer LJ: Nutritional status affects renal 3-methylhistidine handling in humans. Metabolism 39:744-748, 1990
31. Robitaille L, Hoffer LJ: Measurement of branched chain amino acids in blood plasma by high-performance liquid chromatography. Can J Physiol Pharmacol 66:613-617, 1988
32. Lariviere F, Kupranycz D, Chiasson J-L, et al: Plasma leucine kinetics and urinary nitrogen excretion in intensively-treated diabetes mellitus. Am J Physiol 263:E173-E179, 1992
33. Rigalleau V, Blanchetier V, Combe C, et al: A low-protein diet improves insulin sensitivity of endogenous glucose production in predialytic uremic patients. Am J Clin Nutr 65:1512-1516, 1997
34. Brodsky IG, Robbins DC, Hiser E, et al: Effects of low-protein diets on protein metabolism in insulin-dependent diabetes mellitus patients with early nephropathy. J Clin Endocrinol Metab 75:351-357, 1992
35. Pacy PJ, Price GM, Halliday D, et al: Nitrogen homeostasis in man: The diurnal responses of protein synthesis and degradation and amino acid oxidation to diets with increasing protein intakes. Clin Sci 86:103-118, 1994
36. Quevedo MR, Price GM, Halliday D, et al: Nitrogen homeostasis in man: Diurnal changes in nitrogen excretion, leucine oxidation and whole body leucine kinetics during a reduction from a high to a moderate protein intake. Clin Sci 86:185-193, 1994
37. Brodsky IG, Devlin JT: Effects of dietary protein restriction on regional amino acid metabolism in insulin-dependent diabetes mellitus. Am J Physiol 270:E148-E157, 1996
38. Stuart CA, Shangraw RE, Peters EJ, et al: Effect of dietary protein on bed-rest - related changes in whole-body-protein synthesis. Am J Clin Nutr 52:509-514, 1990
39. Goodship THJ, Mitch WE, Hoerr RA, et al: Adaptation to low-protein diets in renal failure: Leucine turnover and nitrogen balance. J Am Soc Nephrol 1:66-75, 1990
40. Zello GA, Telch J, Clarke R, et al: Reexamination of protein requirements in adult male humans by end-product measurements of leucine and lysine metabolism. J Nutr 122:1000-1008, 1992
41. Waterlow JC: The requirements of adult man for indispensable amino acids. Eur J Clin Nutr 50:S151-S179, 1997
42. Tessari P: Effects of insulin on whole-body and regional amino acid metabolism. Diabetes Metab Rev 10:253-285, 1994
43. Robert JJ, Bier D, Schoeller D, et al: Effects of intravenous glucose on whole body leucine dynamics, studied with 1-13C-leucine, in healthy young and elderly adults. J Gerontol 39:673-681, 1984
44. Motil KJ, Matthews DE, Bier DM, et al: Whole-body leucine and lysine metabolism: Response to dietary protein intake in young men. Am J Physiol 240:E712-E721, 1981
45. Bingham SA, Cummings JH: Urine nitrogen as an independent validatory measure of dietary intake: A study of nitrogen balance in individuals consuming their normal diet. Am J Clin Nutr 42:1276-1289, 1985
46. Munro HN: General aspects of the regulation of protein metabolism by diet and hormones, in Munro HN, Allison JB (eds): Mammalian Protein Metabolism, vol 1. New York, NY, Academic, 1964, pp 381-481
47. Carraro F, Wolfe RR: High-protein intake alters the response of fasting in normal human subjects. Am J Clin Nutr 55:959-962, 1992
48. Nuttall FQ, Mooradian AD, Gannon MC, et al: Effect of protein ingestion on the glucose and insulin response to a standardized oral glucose load. Diabetes Care 7:465-470, 1984
49. Nuttall FQ, Gannon MC: Plasma glucose and insulin response to macronutrients in nondiabetic and NIDDM subjects. Diabetes Care 14:824-838, 1991
50. Gin H, Aparicio M, Potaux L, et al: Reduced albuminuria and improved insulin sensitivity after dietary protein restriction in IDDM patients. Diabetes Care 12:369-370, 1989
51. Mak RHK, Turnover C, Thompson T, et al: Glucose metabolism in children with uremia: Effect of dietary phosphate and protein. Kidney Int 22:S206-S209, 1987 (suppl 22)