Human islet allotransplantation: World experience and current status

Digestive Surgery

Volumn 15, Issue 6, 1998, Pages 656-662

  Cretin, N ^a,b   Buhler L ^a   Fournier, B ^a   Caulfield, A ^a   Oberholzer, J ^a   Mentha, G ^a   Morel, Ph ^a  

^a UNIVERSITY HOSPITAL   (Switzerland)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Diabetes, type I; Islet transplantation; Pancreas transplantation

Indexed keywords

15 DEOXYSPERGUALIN; AZATHIOPRINE; C PEPTIDE; CYCLOSPORIN; IMMUNOGLOBULIN; INSULIN; LEFLUNOMIDE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; POLYCLONAL ANTIBODY; RAPAMYCIN; STEROID;

CRYOPRESERVATION; CULTURE MEDIUM; GRAFT REJECTION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INSULIN DEPENDENT DIABETES MELLITUS; ISOLATION AND PURIFICATION; KIDNEY TRANSPLANTATION; MICROENCAPSULATION; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PANCREAS TRANSPLANTATION; POSTOPERATIVE COMPLICATION; REVIEW;

EID: 0031783537     PISSN: 02534886     EISSN: None     Source Type: Journal    
DOI: 10.1159/000018672     Document Type: Review

References (72)

1. Natan DM, Fogel H, Norman D, Russell PS, Tolkoff-Rubin N, Delmonico FL, Auchincloss H, Camuso J, Cosimi AB: Long-term metabolic and quality of life results with pancreatic/renal transplantation in insulin-dependent diabetes mellitus. Transplantation 1991;52:85-91.
2. London NJM, Bell PRF: Pancreas and islet transplantation. Br J Surg 1992;79:6-7.
3. Dubernard JM, Rahbar M, Martin X, Laftavi MR, Lefrancois N: Pancreatic transplantation. Transplant Proc 1995;27:2641-2643.
4. International Pancreas Transplant Registry. Newsletter No 1, vol 6, 1997.
5. Sutherland DER: Pancreas and islet transplantation: Now and then. Transplant Proc 1996; 125:881-884.
6. Rosen CB, Frohnert PP, Velosa JY, Engen DE, Sterioff S: Morbidity of pancreas transplantation during cadaveric renal transplantation. Transplantation 1991;51:123-127.
7. Brayman KL, Stephanian E, Matas AJ, Schmidt W, Payne WD, Sutherland DER, Gores PF, Najarian JS, Dunn DL: Analysis of infectious complications occurring after solidorgan transplantation. Arch Surg 1992;127:38-48.
8. Schulak JY, Mayes JT, Hricik DE: Combined kidney and pancreas transplantation. Arch Surg 1990;125:881-884.
9. Sutherland DER, Gruessner A, Moudry-Munns KC: Tabulation of cases from the International Pancreas Transplant Registry (IPTR) and analysis of United Network for Organ Sharing (UNOS) United States of America Pancreas Transplant Registry data according to multiple variables. Transplant Proc 1993;25: 1707-1709.
10. Banting FG, Best C: The internal secretion of the pancreas. Lab Clin Med 1922;7:251-266.
11. Williams PW: Notes on diabetes treated with extract and by grafts of sheep's pancreas. Br Med J 1894;iii:1303.
12. Pybus FC: Notes on suprarenal and pancreatic grafting. Lancet 1924;ii:550.
13. Moskalewski S: Isolation and culture of the islets of Langerhans of the guinea pig. Gen Comp Endocrinol 1965;5:342-353.
14. Lacy PE, Kostianovsky M: Method for the isolation of intact islets of Langerhans from the rat pancreas. Diabetes 1967;16:35-39.
15. Ballinger WF, Lacy PE: Transplantation of intact pancreatic islets in rats. Surgery 1972;72: 175-186.
16. Sutherland DER, Steffes MW, Mauer SM, Najarian JS: Isolation of human and porcine islets of Langerhans and islet transplantation in pigs. J Surg Res 1974;16:102-111.
17. Alejandro R, Cutfield R, Shienvold FL, Latif Z, Mintz DH: Successful long-term survival of pancreatic islet allografts in spontaneous or pancreatectomy-induced diabetes in dogs. Diabetes 1985;34:825-828.
18. Warnock GL, Cattral MS, Rajotte RV: Normoglycemia after implantation of purified islet cells in dogs. Can J Surg 1988;31:421-426.
19. Mirkovitch V, Campiche M: Successful intrasplenic autotransplantation of pancreatic tissue in totally pancreatectomised dogs. Transplantation 1976;21:265-269.
20. Najarian JS, Sutherland DER, Matas AJ, Steffes MW, Simmons RL, Goetz FC: Human islet transplantation: A preliminary report. Transplant Proc 1977;9:233-236.
21. Ricordi C, Lacy PE, Finke EH, Olack BJ, Scharp DW: Automated method for isolation of human pancreatic islets. Diabetes 1988;37: 413-420.
22. Goetz FC: Evaluating the benefits of human islet transplantation. Diabetes 1980;29:52-55.
23. Leblond V, Sutton L, Doretn R, Davi F, Bitker MO, Gabarre J, Charlotte F, Ghoussoub JJ; Fourcade C, Fischer A, Gandjbakhch I, Binet JL, Raphael M: Lymphoproliferative disorders after organ transplantation: A report of 24 cases observed in a single center. J Clin Oncol 1995;13:961-968.
24. Morrison VA, Dunn DL, Manivel JC, Gajl-Peczalska KJ, Peterson BA: Clinical characteristics of post-transplant lymphoproliferative disorders. Am J Med 1994;97:14-24.
25. Ricordi C, Tzakis AG, Caroll B, Zeng Y, Rodriguez Rilo HL, Alejandro R, Shapiro R, Fung JJ, Demetris AJ, Mintz DH, Starzl E: Human islet isolation and allotransplantation in 22 consecutive cases. Transplantation 1992;53: 407-414.
26. Carroll PB, Rilo HLR, Alejandro R, Zeng Y, Khan R, Fontes P, Tzakis G, Carr B, Ricordi C: Long-term (> 3-year) insulin independence in a patient with pancreatic islet cell transplantation following upper abdominal exenteration and liver replacement for fibrolamellar hepatocellular carcinoma. Transplantation 1995;59: 875-879.
27. Brunicardi FC, Mullen Y: Issues in clinical islet transplantation. Pancreas 1994;9:281-290.
28. Bretzel RG, Hering BJ, Brendel MD, Schultz AO, Schultz B, Vietzke R, Federlin K, Boedeker RH, Gruessner A, Sutherland DER: International Islet Transplant Registry. Newsletter No 7, vol 6, 1996.
29. Memsic L, Busuttil RW, Traverso LW: Bleeding esophageal varices and portal vein thrombosis after pancreatic mixed-cell autotransplantation. Surgery 1984;95:238-242.
30. Shapiro AMJ, Lakey JRT, Rajotte RV, Warnock GL, Friedlich MS, Jewell LD, Kneteman NM: Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation 1995;59:1060-1063.
31. Cameron JL, Mehigan DG, Broe PJ, Zuidema GD: Diostal pancreatectomy and islet autotransplantation for chronic pancreatitis. Ann Surg 1981;193:312-317.
32. Mittal VK, Toledo-Pereyra LH, Sharma M, Ramaswamy K, Puri VK, Cortez JA, Gordon D: Acute portal hypertension and diseminated intravascular coagulation following pancreatic islet autotransplantation after subtotal pancreatectomy. Transplantation 1981;31:302-304.
33. Toledo-Pereyra LH, Rowlett AL, Cain W, Rosenberg JC, Gordon DA, Mackenzic GH: Hepatic infarction following intraportal islet cell autotransplantation after near total pancreatectomy. Transplantation 1984;38:88-89.
34. Gray DW: The role of exocrine tissue in pancreatic islet transplantation. Transplant Int 1989;2:41-45.
35. Warnock GL, Ellis D, Rajotte RV, Davidson I, Baekkeskos S, Egebjerg J: Studies of the isolation and viability of human islets of Langerhans. Transplantation 1988;45:957-963.
36. Olack B, Swanson C, McLear M, Lonfwith J, Scharp D, Lacy PE: Islet purification using Euro-Ficoll gradients. Transplant Proc 1991; 23:774-776.
37. Robertson GSM, Chadwick DR, Contractor H, James RF, London NJM: The optimization of large-scale density gradient isolation of human islets. Acta Diabetol 1993;30:93-98.
38. De Duve C: Tissue fractionation, past and present. J Cell Biol 1971;50:20-50.
39. Lake SP, Basset PD, Larkins A, Revell J, Walczak K, Chamberlain J, Rumford GM, London NJM, Weitch PS, Bell PR: Large-scale purification of human islets utilizing discontinuous albumin gradient on IBM 2991 cell separator. Diabetes 1989;38:143-145.
40. London NJM, Robertson GSM, Chadwick DR: Purification of human pancreatic islets by large scale continuous density gradient centrifugation. Horm Metab Res 1993;25:6.
41. Van Der Burg MP, Gooszen HG, Ploeg RJ, Guicherit OR, Scherft JP, Terpstra JL, Bruijn JA, Frolich M: Pancreatic islet isolation with UW solution: A new concept. Transplant Proc 1990;22:2050-2051.
42. Robertson GSM, Chadwick D, Contractor H, Rose S, Chamberlain R, Clayton H, Bell PR, James RF, London NJM: Storage of human pancreatic digest in University of Wisconsin solution significantly inmproves subsequent islet purification. Br J Surg 1992;79:899-902.
43. Conget I, Sarri Y, Novials A, Casamitjana R, Vives M, Gomis R: Functional properties of isolated human pancreatic islets beneficial effects of culture and exposure to high glucose concentrations. Diabète Métab 1994;20:99-107.
44. Lucas-Clerc C, Massart C, Campion JP, Launois B, Nicol M: Long-term culture of human pancreatic islets in an extracellular matrix: Morphological and metabolic effects. Mol Cell Endocrinol 1993;94:9-20.
45. Holmes MA, Clayton HA, Chadwick DR, Bell PR, London NJM, James RF: Functional studies of rat, porcine and human pancreatic islets cultured in ten commercially available media. Transplantation 1995;60:854-860.
46. Socci C, Davalli AM, Maffi P, Falqui L, Secchi A, Bertuzzi F, Vignali A, Magistretti P, Zammarchi O, Scaglia L, Gavazzi F, Piemonti L, De Nittis P, Ferrari P, De Carlo V, Pozza G: Allotransplantation to fresh and cryopreserved islets in patients with type I diabetes: Two-year experience. Transplant Proc 1993;25:898-991.
47. Kneteman NM, Alderson D, Scharp DW, Lacy PE: Prolonged cryopreservation of purified human pancreatic islets. Diabetes 1989;38:176-178.
48. Di Carlo A, Scharp DW, Gingerich RL, Giannarelli R, Ansara M, Olack BJ, Swanson CJ, Navalesi R: Insulin and glucagon release from isolated, perifuscd human islets following low-temperature culture and cryopreservation. Transplant Proc 1994;26:821-822.
49. Jindal R, Gray D: Preservation and storage of pancreatic islets. Transplantation 1994;57: 317-321.
50. Warnock GL, Gray DW, McShane P, Peters M, Morris PJ: Survival of cryopreserved isolated adult human pancreatic islets of Langerhans. Transplantation 1987;44:75-82.
51. Rajotte RV, Warnock GL, Kenteman NM: Cryopreservation of insulin-producing tissue in rats and dogs. World J Surg 1984;8:179-186.
52. Kneteman NM, Rajotte RV: Isolation and cryopreservation of human pancreatic islets. Transplant Proc 1986;18:182-185.
53. Rajotte RV, Evans MG, Warnock GL, Kneteman NM: Islet cryopreservation. Horm Metab Res 1989;25:72-81.
54. Rajotte RV: Cryopreservation of pancreatic islets. Transplant Proc 1994;26:395-396.
55. Kaufman DB, Morel P, Field MJ, Munn SR, Sutherland DER: Purified canine islet autografts. Functional outcome as influenced by islet number and implantation site. Transplantation 1990;50:385-391.
56. Gray DW: Islet isolation and transplantation techniques in the primate. Surg Gynecol Obstet 1990;170:225-232.
57. Altman JJ, Cugnenc PH, Tessier C, Capeau J, Adam R, Bismuth H, Saye A, Beaugrand M, Bethoux JP: Epiploic flap: A new site for islet implantation in man: Horm Metab Res 1990; 25:136-137.
58. Scharp DW, Lacy PE, Santiago JV, McCullough CS, Weide LG, Boyle PJ, Falqui L, Marchetti P, Ricordi C, Gingerich RL, Jaffe AS, Cryer PE, Hanto DW, Anderson CB, Flye MW: Results of our first nine intraportal islet allografts in type I insulin-dependent diabetic patients. Transplantation 1991;51:76-85.
59. Sccchi A, Socci C, Maffi P, Taglietti MV, Falqui L, Bertuzzi F, De Nittis P, Piemonti L, Scopsi L, Di Carlo V, Pozza G: Islet transplantation in IDDM patients. Diabetologia 1997; 40:225-231.
60. Soon-Shiong P, Lu NZ, Grewal I, Lanza R, Clark W: Prevention of CTL and NK cell-mediated cytotoxicity by microencapsulation. Horm Metab Res 1990;25(suppl)215-219.
61. Cotton CK: Engineering challenges in cell-encapsulation technology. Trends Biotechnol 1996;14:158-162.
62. Cotton CK: Implantable biohybrid artificial organs. Cell Transplant 1995;4:415-436.
63. Krestow M, Lum ZP, Tai IT, Sun AM: Xenotransplantation of microencapsulated fetal rat islets. Transplantation 1991;51:651-655.
64. Lum ZP, Tai IT, Krestow M, Norton J, Vacek I, Sun AM: Prolonged reversal of diabetic state in NOD mice by xenografts of microencapsulated rat islets. Diabetes 1991;40:1511-1516.
65. Lum ZP, Krestow M, Tai IT, Vacek I, Sun AM: Xenografts of rat islets into diabetic mice. Transplantation 1992;53:1180-1183.
66. Sun Y, Ma X, Zhou D, Vacek I, Sun AM: Normalization of diabetes in spontaneously diabetic cynomologus monkeys by xenografts of microencapsulated porcine islets without immunosuppression. J Clin Invest 1996;98:1417-1422.
67. Soon-Shiong P, Feldmann E, Nelson R, Komtedebbe J, Smidsrod O, Skjak-Braek G, Espevik T, Heintz E, Lee M: Successful reversal of spontaneous diabetes in dogs by intraperitoneal microencapsulated islets. Transplantation 1992;54:769-774.
68. Soon-Shiong P, Heintz RE, Merideh N, Yao Z, Zheng T, Murphy M, Moloney MK, Schmehl M, Harris M: Insuline-independence in a type I diabetic patient after encapsulated islet transplantation. Lancet 1994;343:950-951.
69. Scharp DW, Swanson CJ, Olack BJ, Latta PP, Hegre OD, Doherty EJ, Gentile FT, Flavin KS, Ansara MF, Lacy PE: Protection of encapsu-lated human islets implanted without immunosuppression in patients with type I or type II diabetes and nondiabetic control subjects. Diabetes 1994;43:1167-1170.
70. Calafiore R, Basta G, Falorni A, Brotzy G, Alfani D, Cortesini R, Brunetti P: Vascular graft of microencapsulated human pancreatic islets in nonimmunosuppressed diabetic recipients: Preliminary results. Diabetes Nutr Metab 1991;4:45-48.
71. Groth CG, Hering BJ, Geier C, Bretzel RG, Federlin K: Immunosuppression in pancreatic islet cell transplantation. Transplant Proc 1994;26:2756.
72. Gremlich S, Roduit R, Thorens B: Dexamethasone induces posttranslational degradation of GLUT2 and inhibition of insulin secretion in isolated pancreatic B cells. J Biol Chem 1997; 272:3216-3222.