Regulation of plasminogen activator inhibitor-1 mRNA accumulation by basic fibroblast growth factor and transforming growth factor-β1 in cultured rat astrocytes

Journal of Neurochemistry

Volumn 71, Issue 5, 1998, Pages 1944-1952

  Treichel, Julia A ^a   Reddington, Martin ^a,b   Kreutzberg, Georg W ^a  

^a MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^b Human Frontier Science Program Organization   (France)

Author keywords

Cytokines; Glia; mRNA stabilization; Proteases; Transcription

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; MESSENGER RNA; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL ACTIVATION; CONTROLLED STUDY; GLIA CELL; MESSENGER RNA SYNTHESIS; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0031783077     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71051944.x     Document Type: Article

References (67)

1. Akiyama H., Ikeda K., Kondo H., Kato M., and McGeer P. L. (1993) Microglia express the type 2 plasminogen activator inhibitor in the brain of control subjects and patients with Alzheimer's disease. Neurosci. Lett. 164, 233-235.
2. 1 pig kidney cells treated with calcitonin but not with 8-bromocyclic AMP. J. Biol. Chem. 263, 6183-6187.
3. Baron-Van Evercooren A., LePrince P., Register B., Lefebvre P. P., Delree P., Selak I., and Moonen G. (1987) Plasminogen activators in developing peripheral nervous system, cellular origin and mitogenic effect. Dev. Brain Res. 36, 101-108.
4. Blasi F., Vassalli J.-D., and Dano K. (1987) Urokinase-type plasminogen activator: proenzyme, receptor, and inhibitor. J. Cell Biol. 104, 801-804.
5. Busso N., Nicodeme E., Chesne C., Guillouzo A., Belin D., and Hyafil F. (1994) Urokinase and type 1 plasminogen activator inhibitor production by normal human hepatocytes: modulation by inflammatory agents. Hepatology 20, 186-190.
6. Campbell I. K., Wojta J., Novak U., and Hamilton J. A. (1994) Cytokine modulation of plasminogen activator inhibitor-1 (PAI-1) production by human articular cartilage and chondrocytes. Down-regulation by tumor necrosis factor α and up-regulation by transforming growth factor-β and basic fibroblast growth factor. Biochim. Biophys. Acta 1226, 277-285.
7. Carroll P. M., Tsirka S. E., Richards W. G., Frohman M. A., and Strickland S. (1994) The mouse tissue plasminogen activator gene 5′ flanking region directs appropriate expression in the development and a seizure-enhanced response in the CNS. Development 120, 3173-3183.
8. Chomczynski P. and Sacchi N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
9. Danø K., Andreasen P. A., Grodahl-Hansen J., Kristensen P., Nielsen L. S., and Skriver L. (1985) Plasminogen activators, tissue degradation, and cancer. Adv. Cancer Res. 44, 139-266.
10. Dong G., Schulick A. H., Deyoung M. B., and Dichek D. A. (1996) Identification of a cis-acting sequence in the human plasminogen activator inhibitor type-1 gene that mediates transforming growth factor beta-1 responsiveness in endothelium in vivo. J. Biol. Chem. 271, 29969-29977.
11. Dumler I., Petri T., and Schleuning W.-D. (1994) Induction of c-fos gene expression by urokinase-type activator in human ovarian cells. FEBS Lett. 343, 103-106.
12. Flanders K. C., Lüdecke G., Renzing J., Hamm C., Cissel D. S., and Unsicker K. (1993) Effects of TGF-βs and bFGF on astroglial cell growth and gene expression in vitro. Mol. Cell. Neurosci. 4, 406-417.
13. Flaumenhaft R. and Rifkin D. B. (1992) Cell density dependent effects of TGF-β demonstrated by a plasminogen activator-based assay for TGF-β1. J. Cell. Physiol. 152, 48-55.
14. Friedman G. C. and Seeds N. W. (1994) Tissue plasminogen activator expression in the embryonic nervous system. Dev. Brain Res. 81, 41-49.
15. Frey U., Mueller M., and Kuhl D. (1996) A different form of long-lasting potentiation revealed in tissue plasminogen activator mutant mice. J. Neurosci. 16, 2057-2063.
16. García-Rocha M., Avila J., and Armas-Portela R. (1994) Tissue-type plasminogen activator (tPA) is the main plasminogen activator associated with isolated rat nerve growth cones. Neurosci. Lett. 180, 123-126.
17. Goldsmith E. J. and Mottonen J. (1994) Serpins: the uncut version. Structure 2, 241-244.
18. Gualandris A., Jones T. E., Strickland S., and Tsirka S. E. (1996) Membrane depolarization induces calcium-dependent secretion of tissue plasminogen activator. J. Neurosci. 16, 2220-2225.
19. Hamilton J. A., Whitty G. A., Last K., Royston K., Hart P. H., and Burgess D. R. (1992) Interleukin-4 suppresses plasminogen activator inhibitor-2 formation in stimulated human monocytes. Blood 80, 121-125.
20. Hamilton J. A., Wojta J., Gallichio M., McGrath K., and Filonzi E. L. (1993a) Contrasting effects of transforming growth factor-β and IL-1 on the regulation of plasminogen activator inhibitors in human synovial fibroblasts. J. Immunol. 151, 5154-5161.
21. Hamilton J. A., Whitty G. A., Wojta J., Gallichio M., McGrath K., and Ianches G. (1993b) Regulation of plasminogen activator inhibitor-1 levels in human monocytes. Cell. Immunol. 152, 7-17.
22. Harrison T. M., Chidgey M. A., and Uff S. (1996) Novel markers for constitutive secretion used to show that tissue-plasminogen activator is sorted to the regulated pathway in transfected PC12 cells. Cell Biol. Int. 20, 293-299.
23. Heaton J. H., Kathju S., and Gelehrter T. D. (1992) Transcriptional and posttranscriptional regulation of type 1 plasminogen activator inhibitor and tissue-type plasminogen activator gene expression in HTC rat hepatoma cells by glucocorticoids and cyclic nucleotides. Mol. Endocrinol. 6, 53-60.
24. Huang Y. Y., Bach M. E., Lipp H. P., Zhuo M., Wolfer D. P., Hawkins R. D., Schoonjans L., Kandel E. R., Godfraind J. M., Mulligan R., Collen D., and Carmaliet P. (1996) Mice lacking the gene encoding tissue-type plasminogen activator show a selective interference with late-phase long-term potentiation in both Schaffer collateral and mossy fiber pathways. Proc. Natl. Acad. Sci. USA 93, 8699-8704.
25. Hughes R. A., Sendtner M., and Thoenen H. (1993) Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J. Neurosci. Res. 36, 663-671.
26. Hunter K. E., Sporn M. B., and Davies A. M. (1993) Transforming growth factor-βs inhibit mitogen-stimulated proliferation of astrocytes. Glia 7, 203-211.
27. Kiefer R., Lindholm D., and Kreutzberg G. W. (1993a) Interleukin-6 and transforming growth factor-β1 mRNAs are induced in rat facial nucleus following motoneuron axotomy. Eur. J. Neurosci. 5, 775-781.
28. Kiefer R., Gold R., Gehrmann J., Lindholm D., Wekerle H., and Kreutzberg G. W. (1993b) Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. J. Neurosci. Res. 36, 391-398.
29. Krystosek A. and Seeds N. W. (1978) Plasminogen activator production by cultures of developing cerebellum. Fed. Proc. 37, 1702.
30. Lazar P., Reddington M., Streit W., Raivich G., and Kreutzberg G. W. (1991) The action of calcitonin gene-related peptide on astrocyte morphology and cyclic AMP accumulation in astrocyte cultures from neonatal rat brain. Neurosci. Lett. 130, 99-102
31. LePrince P., Bonvoisin C., Rogister B., Mazyservais C., and Moonen G. (1996) Protein kinase-dependent and staurosporine-dependent induction of neunte outgrowth and plasminogen activator activity in PC12 cells. Biochem. Pharmacol. 52, 1399-1405.
32. Lindholm D., Castren E., Kiefer R., Zafra F., and Thoenen H. (1992) Transforming growth factor-β1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J. Cell Biol. 117, 395-400.
33. Logan A. and Berry M. (1993) Transforming growth factor-β1 and basic fibroblast growth factor in the injured CNS. Trends Pharmacol. Sci. 14, 337-343.
34. Logan A., Berry M., Gonzales A. M., Fratschy S. A., Sporn M. B., and Baird A. (1990) Effects of transforming growth factor β1 on scar production in the injured central nervous system of the rat. Eur. J. Neurosci. 6, 355-363.
35. Loskutoff D. J. (1991) Regulation of PAI-1 gene expression. Fibrinolysis 5, 197-206.
36. Lyons R. M., Keski-Oja J., and Moses H. L. (1988) Proteolytic activation of latent transforming growth factor-beta from fibroblast-conditioned medium. J. Cell Biol. 106, 1659-1665.
37. Lyons R. M., Gertry L. E., Purchio A. F., and Moses H. L. (1990) Basic fibroblast growth factor-induced activation of latent transforming growth factor β in endothelial cells: regulation of plasminogen activator activity. J. Cell Biol. 110, 1361-1367.
38. Moser T. L., Enghild J. J., Pizzo S. V., and Stack M. S. (1993) The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator. J. Biol. Chem. 268, 18917-18923.
39. Nagase H., Enghild J. J., Suzuki K., and Salvesen G. (1990) Stepwise activation mechanism of the precursor of matrix metalloproteinase 3 (stromelysin) by proteases and (4-aminophenyl)mercuric acetate. Biochemistry 29, 5783-5789.
40. Nakajima K., Tsuzaki N., Shimojo M., Hamanoue M., and Kohsaka S. (1992) Microglia isolated from rat brain secrete a urokinase-type plasminogen activator. Brain Res. 577, 285-292.
41. Nakajima K., Reddington M., Kohsaka S., and Kreutzberg G. W. (1996) Induction of urokinase-type plasminogen activator in rat facial nucleus by axotomy of the facial nerve. J. Neurochem. 66, 2500-2505.
42. Parmer R. J., Mahata M., Mahata S., Sebald M. T., O'Connor D. T., and Miles L. A. (1997) Tissue plasminogen activator (tPA) is targeted to the regulated secretory pathway. Catecholamine storage vesicles as a reservoir for the rapid release of tPA. J. Biol. Chem. 272, 1976-1982.
43. Qian Z., Gilbert M. E., Colicos M. A., Kandel E. R., and Kuhl D. (1993) Tissue-plasminogen activator is induced as an immediate-early gene during seizure, kindling and long-term potentiation. Nature 361, 453-457.
44. Reddington M., Haas C. A., and Kreutzberg G. W. (1994) The plasminogen activator system in neurons and glia during motoneuron regeneration. Neuropathol. Appl. Neurobiol. 20, 188-190.
45. Rogister B., Leprince P., Pettmann B., Labourdette G., Sensenbrenner M., and Moonen G. (1988) Brain basic fibroblast growth factor stimulates the release of plasminogen activators by newborn rat cultured astroglial cells. Neurosci. Lett. 91, 321-326.
46. Saksela O. and Rifkin D. B. (1988) Cell-associated plasminogen activation: regulation and physiological functions. Annu. Rev. Cell Biol. 4, 93-126.
47. Sandler M. A., Zhang J.-N., Westerhausen D. R. Jr., and Billadello J. J. (1994) A novel protein interacts with the major transforming growth factor-β responsive element in the plasminogen activator inhibitor type-1 gene. J. Biol. Chem. 269, 21500-21504.
48. Sappino A.-P., Madani R., Huarte J., Belin D., Kiss J. Z., Wohlwend A., and Vassalli J.-D. (1993) Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92, 679-685.
49. Sato Y. and Rifkin D. B. (1989) Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-β1-like molecule by plasmin during co-culture. J. Cell Biol. 106, 309-315.
50. Seeds N. W., Williams B. L., and Bickford P. C. (1995) Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning. Science 270, 1992-1994.
51. Seeds N. W., Friedman G., Hayden S., Thewke D., Haffke S., McGuire P., and Krystosek A. (1996) Plasminogen activators and their interaction with the extracellular matrix in neural development plasticity and regeneration. Semin. Neurosci. 8, 405-412.
52. Soreq H. and Miskin R. (1983) Plasminogen activator in the developing rat cerebellum: biosynthesis and localisation in granular neurons. Dev. Brain Res. 11, 149-158.
53. Spranger M., Lindholm D., Bandtlow C., Heumann R., Gnahn H., Näher-Noé M., and Thoenen H. (1990) Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo. Eur. J. Neurosci. 2, 69-76.
54. Sumi Y., Dent M. A. R., Owen D. E., Seeley P. J., and Morris R. J. (1992) The expression of tissue and urokinase-type plasminogen activators in neural development suggests different modes of proteolytic involvement in neuronal growth. Development 116, 625-637.
55. Thalacker F. W. and Nilsen-Hamilton M. (1992) Opposite and independent actions of cyclic AMP and transforming growth factor β in the regulation of type 1 plasminogen activator inhibitor expression. Biochem. J. 287, 855-862.
56. Toshniwal P. K., Tiku M. L., Tiku K., and Skosey J. L. (1987) Secretion of plasminogen activators by cerebral astrocytes and its modulation. J. Neurol. Sci. 80, 307-321.
57. Tranque P., Robbins R., Naftolin F., and Andrade-Gordon P. (1992) Regulation of plasminogen activators and type-1 plasminogen activator inhibitor by cyclic AMP and phorbol ester in rat astrocytes. Glia 6, 163-171.
58. Tsirka S. E., Rogeove A. D., and Strickland S. (1996) Neuronal cell death and tPA. Nature 384, 123-124.
59. van der Wal E., Gomez-Pinilla F., and Cotman C. W. (1993) Transforming growth factor-β1 is in plaques in Alzheimer and Down pathologies. Neuroreport 4, 69-72.
60. Vassalli J.-D., Sappino A.-P., and Belin D. (1991) The plasminogen activator/plasmin system. J. Clin. Invest. 88, 1067-1072.
61. Virji M. A. G., Vassalli J.-D., Estensen R. D., and Reich E. (1980) Plasminogen activator of islets of Langerhans: modulation by glucose and correlation with insulin production. Proc. Natl. Acad. Sci. USA 77, 875-879.
62. Wanaka A., Johnson E. J., and Milbrandt J. (1990) Localization of FGF receptor mRNA in the adult rat central nervous system by in situ hybridization. Neuron 5, 267-281.
63. Westerhausen D. R. Jr., Hopkins W. E., and Billadello J. J. (1991) Multiple transforming growth-factor-β-inducible elements regulate expression of the plasminogen activator inhibitor-type-1 gene in HepG2 cells. J. Biol. Chem. 266, 1092-1100.
64. Williams E. J., Furness J., Walsh F. S., and Doherty P. (1994) Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin. Neuron 13, 583-594.
65. Wojta J., Gallichio M., Zoellner H., Hufnagl P., Last K., Filonzi E. L., Binder B. R., Hamilton J. A., and McGrath K. (1993) Thrombin stimulates expression of tissue-type plasminogen activator and plasminogen activator inhibitor type 1 in cultured human vascular smooth muscle cells. Thromb. Haemost. 70, 469-474.
66. Yamamoto M., Sawaya R., Mohanam S., Loskutoff D. J., Bruner J. M., Rao V. H., Oka K., Tomonaga M., Nicolson G. L., and Rao J. S. (1994) Expression and cellular localization of messenger RNA for plasminogen activator inhibitor type 1 in human astrocytomas in vivo. Cancer Res. 54, 3329-3332.
67. Zeheb R. and Gelehrter T. D. (1988) Cloning and sequencing of cDNA for the rat plasminogen activator inhibitor-1. Gene 73, 459-468.