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Volumn 34, Issue 7, 1998, Pages 987-991

Single agent infusional 5-fluorouracil is not effective second-line therapy after raltitrexed (Tomudex®) in advanced colorectal cancer

Author keywords

5 fluorouracil; Chemotherapy; Colorectal cancer; Raltitrexed

Indexed keywords

CARMUSTINE; FLUOROURACIL; MITOMYCIN C; RALTITREXED;

EID: 0031782749     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-8049(98)00017-3     Document Type: Article
Times cited : (6)

References (17)
  • 1
    • 0029164564 scopus 로고
    • ZD1694 (Tomudex): A new thymidylate synthase inhibitor with activity in colorectal cancer
    • Jackman AL, Farrugia DC, Gibson W, et al. ZD1694 (Tomudex): a new thymidylate synthase inhibitor with activity in colorectal cancer. Eur J Cancer 1995, 31A(7/8), 1277-1282.
    • (1995) Eur J Cancer , vol.31 A , Issue.7-8 , pp. 1277-1282
    • Jackman, A.L.1    Farrugia, D.C.2    Gibson, W.3
  • 2
    • 5544237608 scopus 로고    scopus 로고
    • ® (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer
    • ® (raltitrexed) with 5-fluorouracil plus leucovorin in advanced colorectal cancer. Ann Oncol 1996, 7, 961-965.
    • (1996) Ann Oncol , vol.7 , pp. 961-965
    • Cunningham, D.1    Zalcberg, J.R.2    Rath, U.3
  • 3
    • 0029931840 scopus 로고    scopus 로고
    • "tomudex" (ZD 1694): A novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours
    • Cunningham D, Zalcberg J, Smith I, et al. "Tomudex" (ZD 1694): a novel thymidylate synthase inhibitor with clinical antitumour activity in a range of solid tumours. Ann Oncol 1996, 7, 179-182.
    • (1996) Ann Oncol , vol.7 , pp. 179-182
    • Cunningham, D.1    Zalcberg, J.2    Smith, I.3
  • 4
    • 0029930070 scopus 로고    scopus 로고
    • Resistance to Tomudex (ZD1694): Multifactorial in human breast and colon carcinoma cell lines
    • Drake J.C., Allegra C.J., Moran R.G., Johnston P.G. Resistance to Tomudex (ZD1694): multifactorial in human breast and colon carcinoma cell lines. Biochem Pharmacol. 51:1996;1349-1355.
    • (1996) Biochem Pharmacol , vol.51 , pp. 1349-1355
    • Drake, J.C.1    Allegra, C.J.2    Moran, R.G.3    Johnston, P.G.4
  • 5
    • 0029156922 scopus 로고
    • Thymidylate synthase and drug resistance
    • Peters GJ, Van der Wilt CL, Triest B van, et al. Thymidylate synthase and drug resistance. Eur J Cancer 1995, 31A(7/8), 1299-1305.
    • (1995) Eur J Cancer , vol.31 A , Issue.7-8 , pp. 1299-1305
    • Peters, G.J.1    Van Der Wilt, C.L.2    Van Triest, B.3
  • 6
    • 0026637845 scopus 로고
    • Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules
    • Aschele C., Sobrero A., Faderan M.A., Bertino J.R. Novel mechanism(s) of resistance to 5-fluorouracil in human colon cancer (HCT-8) sublines following exposure to two different clinically relevant dose schedules. Cancer Res. 51:1992;1855-1864.
    • (1992) Cancer Res , vol.51 , pp. 1855-1864
    • Aschele, C.1    Sobrero, A.2    Faderan, M.A.3    Bertino, J.R.4
  • 7
    • 0031015454 scopus 로고    scopus 로고
    • Fluorouracil in colorectal cancer - A tale of two drugs: Implications for biochemical modulation
    • Sobrero A.F., Aschele C., Bertino J.R. Fluorouracil in colorectal cancer - a tale of two drugs: implications for biochemical modulation. J Clin Oncol. 15:(1):1997;368-381.
    • (1997) J Clin Oncol , vol.15 , Issue.1 , pp. 368-381
    • Sobrero, A.F.1    Aschele, C.2    Bertino, J.R.3
  • 8
    • 9044245305 scopus 로고    scopus 로고
    • ZD1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer
    • Zalcberg JR, Cunningham D, Van Cutsem E, et al. ZD1694: a novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. J Clin Oncol 1996, 14(3), 716-721.
    • (1996) J Clin Oncol , vol.14 , Issue.3 , pp. 716-721
    • Zalcberg, J.R.1    Cunningham, D.2    Van Cutsem, E.3
  • 9
    • 0344503902 scopus 로고    scopus 로고
    • A pharmacodynamic study of the thymidylate synthase inhibitor Tomudex in advanced colorectal cancer (abstract)
    • Farrugia D, Cunningham D, Danenberg P, et al. A pharmacodynamic study of the thymidylate synthase inhibitor Tomudex in advanced colorectal cancer (abstract). Proc Am Assoc Cancer Res 1997, 38, 615.
    • (1997) Proc Am Assoc Cancer Res , vol.38 , pp. 615
    • Farrugia, D.1    Cunningham, D.2    Danenberg, P.3
  • 10
    • 0001139165 scopus 로고
    • Phase I trial of ZD1694 (Tomudex), a direct inhibitor of thymidylate synthase
    • Sorensen JM, Jordan E, Grem JL , et al. Phase I trial of ZD1694 (Tomudex), a direct inhibitor of thymidylate synthase. Ann Oncol 1994, 5(Suppl. 5), 132.
    • (1994) Ann Oncol , vol.5 , Issue.SUPPL. 5 , pp. 132
    • Sorensen, J.M.1    Jordan, E.2    Grem, J.L.3
  • 11
    • 0001826735 scopus 로고
    • Interactions and cross resistance patterns between various schedules of 5-FU and the new, folate-based thymidylate synthase inhibitor Tomudex (D1694)
    • Harstrick A, Schleucher N, Gonzales A, et al. Interactions and cross resistance patterns between various schedules of 5-FU and the new, folate-based thymidylate synthase inhibitor Tomudex (D1694). Eur J Cancer 1995, 31A(5), S30.
    • (1995) Eur J Cancer , vol.31 A , Issue.5
    • Harstrick, A.1    Schleucher, N.2    Gonzales, A.3
  • 12
    • 0028787690 scopus 로고
    • Fluorouracil: Active in ZD1694 (Tomudex)-resistant cell lines with markedly elevated thymidylate synthase levels
    • Johnston P.G., Behan K.A., Allegra C.J., Drake J.C. Fluorouracil: active in ZD1694 (Tomudex)-resistant cell lines with markedly elevated thymidylate synthase levels. J Natl Cancer Inst. 87:(20):1995;1558-1559.
    • (1995) J Natl Cancer Inst , vol.87 , Issue.20 , pp. 1558-1559
    • Johnston, P.G.1    Behan, K.A.2    Allegra, C.J.3    Drake, J.C.4
  • 13
    • 0027317751 scopus 로고
    • Decreased folylpolyglutamate synthase expression: A novel mechanism of fluorouracil resistance
    • Wang F.S., Achele C., Sobrero A., Chang Y.M., Bertino J.R. Decreased folylpolyglutamate synthase expression: a novel mechanism of fluorouracil resistance. Cancer Res. 53:1993;3677-3680.
    • (1993) Cancer Res , vol.53 , pp. 3677-3680
    • Wang, F.S.1    Achele, C.2    Sobrero, A.3    Chang, Y.M.4    Bertino, J.R.5
  • 14
    • 0345366123 scopus 로고    scopus 로고
    • A prospective randomised trial of protracted venous infusion (PVI) 5-FU with or without mitomycin C in advanced colorectal cancer
    • Ross P, Norman A, Cunningham D, et al. A prospective randomised trial of protracted venous infusion (PVI) 5-FU with or without mitomycin C in advanced colorectal cancer. Br J Cancer 1997, 76(1), 32.
    • (1997) Br J Cancer , vol.76 , Issue.1 , pp. 32
    • Ross, P.1    Norman, A.2    Cunningham, D.3
  • 15
    • 0031014627 scopus 로고    scopus 로고
    • Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy
    • Rougier P, Bugat R, Douillard JY, et al. Phase II study of irinotecan in the treatment of advanced colorectal cancer in chemotherapy-naive patients and patients pretreated with fluorouracil-based chemotherapy. J Clin Oncol 1997, 15(1), 251-260.
    • (1997) J Clin Oncol , vol.15 , Issue.1 , pp. 251-260
    • Rougier, P.1    Bugat, R.2    Douillard, J.Y.3
  • 16
    • 10344253782 scopus 로고    scopus 로고
    • Biweekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil, and leucovorin in patients with metastatic colorectal cancer
    • Bertheault-Cvitkovic F, Jami A, Ithzaki M, et al. Biweekly intensified ambulatory chronomodulated chemotherapy with oxaliplatin, fluorouracil, and leucovorin in patients with metastatic colorectal cancer. J Clin Oncol 1996, 14(11), 2950-2958.
    • (1996) J Clin Oncol , vol.14 , Issue.11 , pp. 2950-2958
    • Bertheault-Cvitkovic, F.1    Jami, A.2    Ithzaki, M.3
  • 17
    • 0028323029 scopus 로고
    • Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma
    • Conti JA, Kemeny N, Seiter K, et al. Trial of sequential trimetrexate, fluorouracil, and high-dose leucovorin in previously treated patients with gastrointestinal carcinoma. J Clin Oncol 1994, 12(4), 695-700.
    • (1994) J Clin Oncol , vol.12 , Issue.4 , pp. 695-700
    • Conti, J.A.1    Kemeny, N.2    Seiter, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.