메뉴 건너뛰기




Volumn 15, Issue 6, 1998, Pages 835-842

The molecular mobility of supercooled amorphous indomethacin as a function of temperature and relative humidity

Author keywords

Amorphous state; Dielectric relaxation; Indomethacin; Water

Indexed keywords

INDOMETACIN;

EID: 0031782493     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011960112116     Document Type: Article
Times cited : (159)

References (46)
  • 1
    • 0030638567 scopus 로고    scopus 로고
    • Characteristics and Significance of the Amorphous State in Pharmaceutical Systems
    • B. C. Hancock and G. Zografi. Characteristics and Significance of the Amorphous State in Pharmaceutical Systems. J. Pharm. Sci. 86:1-12 (1997).
    • (1997) J. Pharm. Sci. , vol.86 , pp. 1-12
    • Hancock, B.C.1    Zografi, G.2
  • 2
    • 0028597539 scopus 로고
    • Crystallization of Indomethacin from the Amorphous State below and above its Glass Transition Temperature
    • M. Yoshioka, B. C. Hancock, and G. Zografi. Crystallization of Indomethacin from the Amorphous State Below and Above its Glass Transition Temperature. J. Pharm. Sci. 83:1700-1705 (1994).
    • (1994) J. Pharm. Sci. , vol.83 , pp. 1700-1705
    • Yoshioka, M.1    Hancock, B.C.2    Zografi, G.3
  • 3
    • 0029056118 scopus 로고
    • Inhibition of Indomethacin Crystallization in Poly(vinylpyrrolidone) Coprecipitates
    • M. Yoshioka, B. C. Hancock, and G. Zografi. Inhibition of Indomethacin Crystallization in Poly(vinylpyrrolidone) Coprecipitates. J. Pharm. Sci. 84:983-986 (1995).
    • (1995) J. Pharm. Sci. , vol.84 , pp. 983-986
    • Yoshioka, M.1    Hancock, B.C.2    Zografi, G.3
  • 4
    • 0031056536 scopus 로고    scopus 로고
    • Effects of Sorbed Water on the Crystallization of Indomethacin from the Amorphous State
    • V. Andronis, M. Yoshioka, and G. Zografi. Effects of Sorbed Water on the Crystallization of Indomethacin from the Amorphous State. J. Pharm. Sci. 86:346-351 (1997).
    • (1997) J. Pharm. Sci. , vol.86 , pp. 346-351
    • Andronis, V.1    Yoshioka, M.2    Zografi, G.3
  • 5
    • 0029015405 scopus 로고
    • The Molecular Mobility of Amorphous Pharmaceutical Solids below Their Glass Transition Temperatures
    • B. C. Hancock, S. L. Shamblin, and G. Zografi. The Molecular Mobility of Amorphous Pharmaceutical Solids Below Their Glass Transition Temperatures. Pharm. Res. 12:799-806 (1995).
    • (1995) Pharm. Res. , vol.12 , pp. 799-806
    • Hancock, B.C.1    Shamblin, S.L.2    Zografi, G.3
  • 6
    • 0030981479 scopus 로고    scopus 로고
    • Molecular Mobility of Supercooled Amorphous Indomethacin, Determined by Dynamic Mechanical Analysis
    • V. Andronis and G. Zografi. Molecular Mobility of Supercooled Amorphous Indomethacin, Determined by Dynamic Mechanical Analysis. Pharm. Res. 14:410-414 (1997).
    • (1997) Pharm. Res. , vol.14 , pp. 410-414
    • Andronis, V.1    Zografi, G.2
  • 8
    • 9544227573 scopus 로고
    • Dependence of the Glass Transition Temperature on Heating and Cooling Rate
    • C. T. Moynihan, A. J. Easteal, J. Wilder, and J. Tucker. Dependence of the Glass Transition Temperature on Heating and Cooling Rate. J. Phys. Chem. 78:2673-2677 (1974).
    • (1974) J. Phys. Chem. , vol.78 , pp. 2673-2677
    • Moynihan, C.T.1    Easteal, A.J.2    Wilder, J.3    Tucker, J.4
  • 9
    • 0016870767 scopus 로고
    • Analysis of Structural Relaxation in Glass Using Rate Heating Data
    • M. DeBolt, A. Esteal, P. Macedo, and C. Moynihan. Analysis of Structural Relaxation in Glass Using Rate Heating Data. J. Amer. Ceram. Soc. 59:16-21 (1976).
    • (1976) J. Amer. Ceram. Soc. , vol.59 , pp. 16-21
    • Debolt, M.1    Esteal, A.2    Macedo, P.3    Moynihan, C.4
  • 10
    • 15144357529 scopus 로고    scopus 로고
    • Moynihan in Ref. 11 has shown that a correlation exists between the activation enthalpy ΔH* and the width of the glass transition. However since the correlation constant is not known a priori for indomethacin, or for any other amorphous material, the method does not really allow for the direct determination of ΔH*
    • Moynihan in Ref. 11 has shown that a correlation exists between the activation enthalpy ΔH* and the width of the glass transition. However since the correlation constant is not known a priori for indomethacin, or for any other amorphous material, the method does not really allow for the direct determination of ΔH*.
  • 11
    • 84986364793 scopus 로고
    • Correlation between the Width of the Glass Transition Region and the Temperature Dependence of the Viscosity of High-Tg Glasses
    • C. T. Moynihan. Correlation Between the Width of the Glass Transition Region and the Temperature Dependence of the Viscosity of High-Tg Glasses. J. Am. Ceram. Soc. 76:1081-1087 (1993).
    • (1993) J. Am. Ceram. Soc. , vol.76 , pp. 1081-1087
    • Moynihan, C.T.1
  • 12
    • 0038427316 scopus 로고
    • Measurement of the Dielectric Properties and Thermal Expansion of Polymers from Ambient to Liquid Helium Temperatures
    • R. D. McCammon and R. N. Work. Measurement of the Dielectric Properties and Thermal Expansion of Polymers from Ambient to Liquid Helium Temperatures. Rev. Sci. Instrum 36:1169-1173 (1965).
    • (1965) Rev. Sci. Instrum , vol.36 , pp. 1169-1173
    • McCammon, R.D.1    Work, R.N.2
  • 13
    • 0343908281 scopus 로고
    • Dielectric measuring techniques
    • A. R. Von Hippel (eds), John Wiley, New York
    • R. F. Field. Dielectric measuring techniques. In A. R. Von Hippel (eds), Dielectric Materials and Applications, John Wiley, New York, 1954.
    • (1954) Dielectric Materials and Applications
    • Field, R.F.1
  • 14
    • 15144348247 scopus 로고
    • Electrical Methods
    • R. A. Fava (eds), Academic Press, New York
    • R. H. Boyd. Electrical Methods. In R. A. Fava (eds), Methods of Experimental Physics, Academic Press, New York, 1980.
    • (1980) Methods of Experimental Physics
    • Boyd, R.H.1
  • 16
    • 0000350738 scopus 로고
    • Dielectric Relaxation in Liquids I. The Representation of Relaxation Behaviour
    • D. W. Davidson. Dielectric Relaxation in Liquids I. The Representation of Relaxation Behaviour. Can. J. Chem. 39:571-594 (1961).
    • (1961) Can. J. Chem. , vol.39 , pp. 571-594
    • Davidson, D.W.1
  • 17
    • 10844287652 scopus 로고
    • Detailed Comparison of the Williams-Watts and Cole-Davidson Functions
    • C. P. Lindsey and G. D. Patterson. Detailed Comparison of the Williams-Watts and Cole-Davidson Functions. J. Chem. Phys. 73:3348-3357 (1980).
    • (1980) J. Chem. Phys. , vol.73 , pp. 3348-3357
    • Lindsey, C.P.1    Patterson, G.D.2
  • 19
    • 33751124528 scopus 로고
    • Nonexponential Relaxations in Strong and Fragile Glass Formers
    • R. Bohmer, K. L. Ngai, C. A. Angell, and D. J. Plazek. Nonexponential Relaxations in Strong and Fragile Glass Formers. J. Chem. Phys. 99:4201-4209 (1993).
    • (1993) J. Chem. Phys. , vol.99 , pp. 4201-4209
    • Bohmer, R.1    Ngai, K.L.2    Angell, C.A.3    Plazek, D.J.4
  • 20
    • 0028416385 scopus 로고
    • Enthalpy Relaxation and Recovery in Amorphous Materials
    • I. M. Hodge. Enthalpy Relaxation and Recovery in Amorphous Materials. J. Non-Cryst. Solids. 169:211-266 (1994).
    • (1994) J. Non-Cryst. Solids. , vol.169 , pp. 211-266
    • Hodge, I.M.1
  • 21
    • 0029831538 scopus 로고    scopus 로고
    • How Does Residual Water Affect the Solid-State Degradation of Drugs in the Amorphous State?
    • E. Y. Shalaev and G. Zografi. How Does Residual Water Affect the Solid-State Degradation of Drugs in the Amorphous State? J. Pharm. Sci. 85: 1137-1141 (1996).
    • (1996) J. Pharm. Sci. , vol.85 , pp. 1137-1141
    • Shalaev, E.Y.1    Zografi, G.2
  • 23
    • 0001062409 scopus 로고
    • C, T-Dependence of the Self Diffusion in Concentrated Aqueous Sucrose Solutions
    • D. Girlich, H. D. Ludemann, C. Buttersack, and C. Buchholz. c, T-Dependence of the Self Diffusion in Concentrated Aqueous Sucrose Solutions. Z. Naturforsch 49:258-264 (1994).
    • (1994) Z. Naturforsch , vol.49 , pp. 258-264
    • Girlich, D.1    Ludemann, H.D.2    Buttersack, C.3    Buchholz, C.4
  • 24
    • 3843117886 scopus 로고
    • Dynamic Viscosity of a Simple Glass-Forming Liquid
    • N. Menon, S. R. Nagel, and D. C. Venerus. Dynamic Viscosity of a Simple Glass-Forming Liquid. Phys. Rev. Lett. 73:963-966 (1994).
    • (1994) Phys. Rev. Lett. , vol.73 , pp. 963-966
    • Menon, N.1    Nagel, S.R.2    Venerus, D.C.3
  • 25
    • 0000866240 scopus 로고
    • Dielectric Relaxations in the Liquid and Glassy States of Glucose and Its Water Mixtures
    • R. Chan, K. Pathmanathan, and G. P. Johari. Dielectric Relaxations in the Liquid and Glassy States of Glucose and Its Water Mixtures. J. Phys. Chem. 90:6358-6362 (1986).
    • (1986) J. Phys. Chem. , vol.90 , pp. 6358-6362
    • Chan, R.1    Pathmanathan, K.2    Johari, G.P.3
  • 26
    • 0031423468 scopus 로고    scopus 로고
    • Spectroscopic Characterization of Interactions between PVP and Indomethacin in Amorphous Molecular Dispersions
    • L. S. Taylor and G. Zografi. Spectroscopic Characterization of Interactions Between PVP and Indomethacin in Amorphous Molecular Dispersions. Pharm. Res. 14:1691-1698 (1997).
    • (1997) Pharm. Res. , vol.14 , pp. 1691-1698
    • Taylor, L.S.1    Zografi, G.2
  • 28
    • 0000805458 scopus 로고    scopus 로고
    • Structural Relaxation and H Bonding in Isomeric Octanols and Their LiCl Solutions by Calorimetry
    • G. Sartor, K. Hofer, and G. P. Johari. Structural Relaxation and H Bonding in Isomeric Octanols and Their LiCl Solutions by Calorimetry. J. Phys. Chem. 100:6801-6807 (1996).
    • (1996) J. Phys. Chem. , vol.100 , pp. 6801-6807
    • Sartor, G.1    Hofer, K.2    Johari, G.P.3
  • 30
    • 0023028276 scopus 로고
    • Some Physicochemical Properties of Glassy Indomethacin
    • E. Fukuoka, M. Makita, and S. Yamamura. Some Physicochemical Properties of Glassy Indomethacin. Chem. Pharm. Bull. 34:4314-4321 (1986).
    • (1986) Chem. Pharm. Bull. , vol.34 , pp. 4314-4321
    • Fukuoka, E.1    Makita, M.2    Yamamura, S.3
  • 31
    • 0029255938 scopus 로고
    • α-Relaxation in the Glass Transition Range of Amorphous Polymers. 1. Temperature Behavior Across the Glass Transition
    • A. Alegria, E. Guerrica-Echevarria, L. Goitiandia, I. Telleria, and J. Colmenero. α-Relaxation in the Glass Transition Range of Amorphous Polymers. 1. Temperature Behavior Across the Glass Transition. Macromolecules 28:1516-1527 (1995).
    • (1995) Macromolecules , vol.28 , pp. 1516-1527
    • Alegria, A.1    Guerrica-Echevarria, E.2    Goitiandia, L.3    Telleria, I.4    Colmenero, J.5
  • 32
    • 0029274708 scopus 로고
    • Physical Aging in Polymer Glasses
    • I. M. Hodge. Physical Aging in Polymer Glasses. Science 267:1945-1947 (1995).
    • (1995) Science , vol.267 , pp. 1945-1947
    • Hodge, I.M.1
  • 33
    • 0742294357 scopus 로고
    • Nature of the Glass Transition and the Glassy State
    • J. H. Gibbs and E. A. DiMarzio. Nature of the Glass Transition and the Glassy State. J. Chem. Phys. 28:373-383 (1958).
    • (1958) J. Chem. Phys. , vol.28 , pp. 373-383
    • Gibbs, J.H.1    Dimarzio, E.A.2
  • 34
    • 0347936294 scopus 로고
    • On the Temperature Dependence of Cooperative Properties in Glass-Forming Liquids
    • G. Adam and J. H. Gibbs. On the Temperature Dependence of Cooperative Properties in Glass-Forming Liquids. J. Chem. Phys. 43:139-146 (1965).
    • (1965) J. Chem. Phys. , vol.43 , pp. 139-146
    • Adam, G.1    Gibbs, J.H.2
  • 35
    • 0028761409 scopus 로고
    • Heat Capacities and Glass Transitions of 1-Propanol and 3-Methylpentane under Pressure. New Evidence for the Entropy Theory
    • S. Takahara, O. Yamamuro, and H. Suga. Heat Capacities and Glass Transitions of 1-Propanol and 3-Methylpentane Under Pressure. New Evidence for the Entropy Theory. J. Non-Cryst. Solids. 171:259-270 (1994).
    • (1994) J. Non-Cryst. Solids. , vol.171 , pp. 259-270
    • Takahara, S.1    Yamamuro, O.2    Suga, H.3
  • 36
    • 0347612478 scopus 로고
    • Calorimetric Study of 3-Bromopentane: Correlation between Structural Relaxation Time and Configurational Entropy
    • S. Takahara, O. Yamamuro, and T. Matsuo. Calorimetric Study of 3-Bromopentane: Correlation Between Structural Relaxation Time and Configurational Entropy. J. Phys. Chem. 99:9589-9592 (1995).
    • (1995) J. Phys. Chem. , vol.99 , pp. 9589-9592
    • Takahara, S.1    Yamamuro, O.2    Matsuo, T.3
  • 37
    • 0021459132 scopus 로고
    • Use of the Adam-Gibbs Equation in the Analysis of Structural Relaxation
    • G. W. Scherer. Use of the Adam-Gibbs Equation in the Analysis of Structural Relaxation. J. Am. Ceram. Soc. 67:504-511 (1984).
    • (1984) J. Am. Ceram. Soc. , vol.67 , pp. 504-511
    • Scherer, G.W.1
  • 38
    • 0026413564 scopus 로고
    • Relaxation in Liquids, Polymers and Plastic Crystals - Strong/Fragile Patterns and Problems
    • C. Angell. Relaxation in Liquids, Polymers and Plastic Crystals - Strong/Fragile Patterns and Problems. J. Non-Cryst. Solids. 131-133:13-31 (1991).
    • (1991) J. Non-Cryst. Solids. , vol.131-133 , pp. 13-31
    • Angell, C.1
  • 39
    • 0025474645 scopus 로고
    • Theories of Relaxation
    • G. W. Scherer. Theories of Relaxation. J. Non-Cryst. Solids. 123:75-89 (1990).
    • (1990) J. Non-Cryst. Solids. , vol.123 , pp. 75-89
    • Scherer, G.W.1
  • 40
    • 0001300435 scopus 로고
    • Effects of Annealing and Prior History on Enthalpy Relaxation in Glassy Polymers. 6. Adam-Gibbs Formulation of Nonlinearity
    • I. M. Hodge. Effects of Annealing and Prior History on Enthalpy Relaxation in Glassy Polymers. 6. Adam-Gibbs Formulation of Nonlinearity. Macromolecules 20:2897-2908 (1987).
    • (1987) Macromolecules , vol.20 , pp. 2897-2908
    • Hodge, I.M.1
  • 42
    • 0028530389 scopus 로고
    • Heat Capacities and Glass Transitions of Ground Amorphous Solid and Liquid- Quenched Glass of Tri-O-Methyl-β-Cyclodextrin
    • I. Tsukushi, O. Yamamuro, and H. Suga. Heat Capacities and Glass Transitions of Ground Amorphous Solid and Liquid-Quenched Glass of Tri-O-Methyl-β-Cyclodextrin. J. Non-Cryst. Solids 175:187-194 (1994).
    • (1994) J. Non-Cryst. Solids , vol.175 , pp. 187-194
    • Tsukushi, I.1    Yamamuro, O.2    Suga, H.3
  • 43
    • 0028401414 scopus 로고
    • Principal Features of Structural Relaxation in Glassy Polymers. A Review
    • J. Mijovic, L. Nicolais, A. D'Amore, and J. M. Kenny. Principal Features of Structural Relaxation in Glassy Polymers. A Review. Polym. Eng. Sci. 34:381-389 (1994).
    • (1994) Polym. Eng. Sci. , vol.34 , pp. 381-389
    • Mijovic, J.1    Nicolais, L.2    D'Amore, A.3    Kenny, J.M.4
  • 44
  • 45
    • 0026415759 scopus 로고
    • Correlation of Polymer Segmental Chain Dynamics with Temperature-Dependent Time-Scale Shifts
    • D. J. Plazek and K. L. Ngai. Correlation of Polymer Segmental Chain Dynamics with Temperature-Dependent Time-Scale Shifts, Macromolecules 24:1222-1224 (1991).
    • (1991) Macromolecules , vol.24 , pp. 1222-1224
    • Plazek, D.J.1    Ngai, K.L.2
  • 46
    • 0030188824 scopus 로고    scopus 로고
    • Strong and Fragile Liquids - A Brief Critique
    • I. M. Hodge. Strong and Fragile Liquids - A Brief Critique. J. Non-Cryst. Solids. 202:164-172 (1996).
    • (1996) J. Non-Cryst. Solids. , vol.202 , pp. 164-172
    • Hodge, I.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.