Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: The impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells

Diabetologia

Volumn 41, Issue 10, 1998, Pages 1194-1198

  Almind, K ^a   Ambye, L ^a   Urhammer, S A ^a   Hansen, T ^a   Echwald, S M ^a   Holst, J J ^b   Gromada, J ^c   Thorens, B ^d   Pedersen, O ^a  

^a STENO DIABETES CENTER   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NOVO NORDISK A S   (Denmark)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

C peptide response; Genetics; GIP receptor; Incretins; Mutations; Transfections; Type II diabetes mellitus

Indexed keywords

AMINO ACID; C PEPTIDE; CYCLIC AMP; DNA; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; RECEPTOR;

ADULT; AGED; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CHINESE HAMSTER; CLINICAL TRIAL; CODON; CONTROLLED STUDY; EXON; FEMALE; FIBROBLAST; GENE FREQUENCY; GENE MUTATION; GENETIC POLYMORPHISM; HOMOZYGOSITY; HUMAN; INTRON; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET BETA CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

ALLELES; ANIMALS; C-PEPTIDE; CELL LINE; CRICETINAE; CRICETULUS; CYCLIC AMP; DIABETES MELLITUS, TYPE 2; DNA MUTATIONAL ANALYSIS; GASTRIC INHIBITORY POLYPEPTIDE; GENE EXPRESSION; GENE FREQUENCY; GLUCOSE TOLERANCE TEST; HOMOZYGOTE; HUMANS; ISLETS OF LANGERHANS; MUTATION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; RECEPTORS, GASTROINTESTINAL HORMONE; TRANSFECTION;

EID: 0031781959     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051051     Document Type: Article

References (10)

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