A placebo-controlled study of three osteocalcin assays for assessment of prednisolone-induced suppression of bone turnover

Journal of Endocrinology

Volumn 159, Issue 1, 1998, Pages 127-131

  Heuck, C ^a   Wolthers, O D ^a,b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b RANDERS REGIONAL HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; MONOCLONAL ANTIBODY; OSTEOCALCIN; PLACEBO; PREDNISOLONE;

ADULT; ARTICLE; BONE METABOLISM; BONE TURNOVER; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HORMONAL REGULATION; HORMONE DETERMINATION; HUMAN; INTERMETHOD COMPARISON; MALE; ORAL DRUG ADMINISTRATION; OSTEOBLAST; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANALYSIS OF VARIANCE; BONE REMODELING; DEPRESSION, CHEMICAL; DOUBLE-BLIND METHOD; FEMALE; FLUOROIMMUNOASSAY; GLUCOCORTICOIDS; HUMANS; IMMUNORADIOMETRIC ASSAY; MALE; MIDDLE AGED; OSTEOCALCIN; PREDNISOLONE; RADIOIMMUNOASSAY;

EID: 0031781136     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1590127     Document Type: Article

References (29)

1. Bland JM & Altman DG 1986 Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986 i 307-310.
2. Blumsohn A, Hannon RA & Eastell R 1995 Apparent instability of osteocalcin in serum as measured with different commercially available immunoassays. Clinical Chemistry 41 318-319.
3. Cecchettin M, Bellometti S, Torri G & Galzigna L 1995 Comparison of commercial osteocalcin assay kits in evaluating osteoporasis. Current Therapeutic Research 56 163-168.
4. Cis Bio International 1994. ELSA-OSTEO. Gif-Sur-Yvette Cedex, France.
5. Cis Bio International 1995. OSTK-PR. Gif-Sur-Yvette Cedex, France.
6. Deftos LJ, Wolfert RL, Hill CS & Burton DW 1992 Two-site assays of bone gla protein (osteocalcin) demonstrate immunochemical heterogeneity of the intact molecule. Clinical Chemistry 38 2318-2321.
7. Delmas PD, Christiansen C, Mann KG & Price PA 1990 Bone Gla protein (osteocalcin) assay standardization report. Journal of Bone and Mineral Research 5 5-11.
8. Diaz Diego EM, Guerrero R & de la Piedra C 1994 Six osteocalcin assays compared. Clinical Chemistry 40 2071-2077.
9. Garaero P, Grimaux M, Seguin P & Delmas PD 1994 Characterization of immunoreactive forms of human osteocalcin generated in viva and in vitro. Journal of Bone and Mineral Research 9 255-264.
10. Gundberg CM, Markowitz ME, Mizruchi M & Rosen JF 1985 Osteocalcin in human serum: a circadian rhythm. Journal of Clinical Endocrinology and Metabolism 60 736-739.
11. Hodsman AB, Toogood JH, Jennings B, Fraher LJ & Baskerville JC 1991 Differential effects of inhaled budesonide and oral prednisolone on serum osteocalcin. Journal of Clinical Endocrinology and Metabolism 72 530-540.
12. Kabi Phannacia Diagnostics AB 1994 Pharmacia CAP system osteocalcin FEIA. Uppsala, Sweden: Kabi Pharmacia Diagnostics AB.
13. Knutsson U, Stierna P, Marcus C, Carlstedt Duke J, Carlstrom K & Bronnegard M 1995 Effects of intranasal glucocorticoids on endogenous glucocorticoid peripheral and central function. Journal of Endocrinology 144 301-310.
14. Lane SJ, Vaja S, Swaminathan R & Lee TH 1996 Effects of prednisolone on bone turnover in patients with corticosteroid resistant asthma. Clinical and Experimental Allergy 26 1197-1201.
15. Lems WF, Jacobs JW, van den Brink HR, van Rijn HJ & Bijlsma JW 1993 Transient decrease in osteocalcin and markers of type 1 collagen turnover during high-dose corticosteroid pulse therapy in rheumatoid arthritis. British Journal of Rheumatology 32 787-789.
16. LoCascio V, Bonucci E, Imbimbo B, Ballanti P, Adami S, Milani S, Tartarotti D & DellaRocca C 1990 Bone loss in response to long-term glucocorticoid therapy. Bone and Mineral 8 39-51.
17. Masters PW, Jones RG, Purves DA, Cooper EH & Cooney JM 1994 Commercial assays for serum osteocalcin give clinically discordant results. Clinical Chemistry 40 358-363.
18. Meeran K, Hattersley A, Burrin J, Shiner R & Ibbertson K 1995 Oral and inhaled corticosteroids reduce bone formation as shown by plasma osteocalcin levels. American Journal of Respiratory and Critical Care Medicine 151 333-336.
19. Morice AH, Morris D & Lawson MP 1996 A comparison of nebulized budesonide with oral prednisolone in the treatment of exacerbations of obstructive pulmonary disease. Clinical Pharmacology and Therapeutics 60 675-678.
20. Nielsen HK, Charles P & Mosekilde L 1988a The effect of single oral doses of prednisone on the circadian rhythm of serum osteocalcin in normal subjects. Journal of Clinical Endocrinology and Metabolism 67 1025-1030.
21. Nielsen HK, Thomsen K, Eriksen EF, Charles P, Storm T & Mosekilde L 1988b The effects of high-dose glucocorticoid administration on serum bone gamma carboxyglutamic acid-containing protein, serum alkaline phosphatase and vitamin D metabolites in normal subjects. Bone and Mineral 4 105-113.
22. Reid IR 1989 Pathogenesis and treatment of steroid osteoporosis. Clinical Endocrinology 30 83-103.
23. Tarallo P, Henny J, Fournier B & Siest G 1990 Plasma osteocalcin: biological variations and reference limits. Scandinavian Journal of Clinical and Laboratory Investigation 50 649-655.
24. Taylor AK, Linkhart SG, Mohan S & Baylink DJ 1988 Development of a new radioimmunoassay for human osteocalcin: evidence of a midmolecule epitope. Metabolism 37 872-877.
25. Toogood JH & Hodsman AB 1991 Effects of inhaled and oral corticosteroids on bone. Annals of Allergy 67 87-90.
26. Tracy RP, Andrianorivo A, Riggs BL & Mann KG 1990 Comparison of monoclonal and polyclonal antibody-based immunoassays for osteocalcin: a study of sources of variation in assay results. Journal of Bone and Mineral Research 5 451-461.
27. Wolthers OD, Riis BJ & Pedersen S 1993 Bone turnover in asthmatic children treated with oral prednisolone or inhaled budesonide. Pediatric Pulmonology 16 341-346.
28. Wolthers OD, Heuck C, Ternowitz T, Heickendorf L, Nielsen HK & Frystyk J 1996 The insulin-like growth factor axis and bone and collagen turnover in children with atopic dermatitis treated with topical glucocorticosteroids. Dermatology 192 337-342.
29. Worth H, Stammen D & Keck E 1994 Therapy of steroid-induced bone loss in adult asthmatics with calcium, vitamin D, and a diphosphonate. American Journal of Respiratory and Critical Care Medicine 150 394-397.