Identification of novel staphylococcal virulence genes by in vivo expression technology

Molecular Microbiology

Volumn 27, Issue 5, 1998, Pages 967-976

  Lowe, Adrian M ^a,b   Beattie, David T ^a,b   Deresiewicz, Robert L ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Virus Research Institute Inc Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL VIRULENCE; GENE EXPRESSION; GENE LOCUS; GENE TECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STAPHYLOCOCCUS;

AGRA; BACTERIA (MICROORGANISMS); MURINAE; POSIBACTERIA; STAPHYLOCOCCUS;

EID: 0031780325     PISSN: 0950382X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2958.1998.00741.x     Document Type: Article

References (41)

1. Ayliffe, G.A.J. (1997) The progressive intercontinental spread of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 24: S74-9.
2. Boyce, J.M. (1997) Epidemiology and prevention of nosocomial infections. In The Staphylococci in Human Disease. Crossley, K.B., and Archer, G.L. (eds). New York: Churchill Livingstone, pp. 309-329.
3. Camilli, A., Beattie, D.T., and Mekalanos, J.J. (1994) Use of genetic recombination as a reporter of gene expression. Proc Natl Acad Sci USA 91: 2634-2638.
4. Camilli, A., and Mekalanos, J.J. (1995) Use of recombinase gene fusions to identify Vibrio cholerae genes induced during infection. Mol Microbiol 18: 671-683.
5. Cheung, A.L., Eberhardt, K.J., Chung, E., Yeaman, M.R., Sullam, P.M., Ramos, M., et al. (1994) Diminished virulence of a sar-/agr-mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest 94: 1815-1822.
6. Deresiewicz, R.L., Flaxenburg, J.A., Chan, M., Finberg, R.W., and Kasper, D.L. (1994) Intracellular expression of toxic shock syndrome toxin 1 in Saccharomyces cerevisiae. Infect Immun 62: 2202-2207.
7. Engler, H.D., and Kapral, F.A. (1992) The production of a bactericidal monoglyceride in staphylococcal abscesses. J Med Microbiol 37: 238-244.
8. Foster, T.J., and McDevitt, D. (1994) Surface-associated proteins of Staphylococcus aureus: their possible roles in virulence. FEMS Microbiol Lett 118: 199-206.
9. Heithoff, D.M., Conner, C.P., Hanna, P.C., Julio, S.M., Hentschel, U., and Mahan, M.J. (1997) Bacterial infection as assessed by in vivo gene expression. Proc Natl Acad Sci USA 94: 934-939.
10. Hienz, S.A., Schennings, T., Heimdahl, A., and Flock, J.-I. (1996) Collagen binding of Staphylococcus aureus is a virulence factor in experimental endocarditis. J Infect Dis 174: 83-88.
11. Hiramatsu, K. (1997) Reduced susceptibility of Staphylococcus aureus to vancomycin - Japan 1996. Morb Mortal Wkly Rep 46: 624-626.
12. Ichikawa, S., and Kaji, A. (1989) Molecular cloning and expression of ribosome releasing factor. J Biol Chem 264: 20054-20059.
13. Janosi, L., Shimizu, I., and Kaji, A. (1994) Ribosome recycling factor (ribosome releasing factor) is essential for bacterial growth. Proc Natl Acad Sci USA 91: 4249-4253.
14. Janosi, L., Hara, H., Zhang, S., and Kaji, A. (1996a) Ribosome recycling by ribosome recycling factor (rrf) - an important but overlooked step of protein biosynthesis. Adv Biophys 32: 121-201.
15. Janosi, L., Ricker, R., and Kaji, A. (1996b) Dual functions of ribosome releasing factor in protein biosynthesis: disassembling the termination complex and preventing translational errors. Biochimie 78: 959-969.
16. Ji, G., Beavis, R., and Novick, R.P. (1997) Bacterial interference caused by autoinducing peptide variants. Science 276: 2027-2030.
17. Kapral, F.A., Smith, S., and Lal, D. (1992) The esterification of fatty acids by Staphylococcus aureus fatty acid modifying enzyme (FAME) and its inhibition by glycerides. J Med Microbiol 37: 235-237.
18. Lazarevic, V., Margot, P., Soldo, B., and Karamata, D. (1992) Sequencing and analysis of the Bacillus subtilis lytRABC divergon: a regulatory unit encompassing the structural genes of the N-acetylmuramoyl-L-alanine amidase and its modifier. J Gen Microbiol 138: 1949-1961.
19. Lee, C.Y., Buranen, S.L., and Ye, Z.-H. (1991) Construction of single-copy integration vectors for Staphylococcus aureus. Gene 103: 101-105.
20. Lee, J.C., Hopkins, C.A., and Pier, G.B. (1985) The role of the Staphylococcus aureus capsule in abscess formation. Zbl Bakt Suppl 14: 219-224.
21. Mahan, M.J., Slauch, J.M., and Mekalanos, J.J. (1993) Selection of bacterial virulence genes that are specifically induced in host tissues. Science 259: 686-688.
22. Mahan, M.J., Tobias, J.W., Slauch, J.M., Hanna, P.C., Collier, R.J., and Mekalanos, J.J. (1995) Antibiotic based selection for bacterial genes that are specifically induced during infection of a host. Proc Natl Acad Sd USA 92: 669-673.
23. Mani, N., Baddour, L.M., Offut, D.Q., Vijaranakul, U., Nadakavukaren, M.J., and Jayasawal, R.K. (1994) Autolysis-defective mutant of Staphylococcus aureus: pathological considerations, genetic mapping, and electron microscopic studies. Infect Immun 62: 1406-1409.
24. Newman, B.J., and Grindley, N.D.F. (1984) Mutants of the gamma-delta resolvase: a genetic analysis of the recombination function. Cell 38: 463-469.
25. Novick, R.P., Projan, S.J., Kornblum, J., Ross, H.F., Ji, G., Kreiswirth, B., et al. (1995) The agr P2 operon: an auto-catalytic sensory transduction system in Staphylococcus aureus. Mol Gen Genet 248: 446-458.
26. Oshida, T., Sugai, M., Komatsuzawa, H., Hong, Y.-M., Suginaka, H., and Tomasz, A. (1995) A Staphylococcus aureus autolysin that has an N-acetylmuramoyl-L-alanine amidase domain and an endo-β-N-acetylglucosaminidase domain: cloning, sequence analysis, and characterization. Proc Natl Acad Sci USA 92: 285-289.
27. Panlilio, A.L., Culver, D.H., Gaynes, R.P., Banerjee, S., Henderson, T.S., Toison, J.S., et al. (1992) Methicillin-resistant Staphylococcus aureus in US hospitals, 1975-91. Infect Control Hosp Epidemiol 13: 582-586.
28. Peng, H.L., Novick, R.P., Kreiswirth, B., Kornblum, J., and Schlievert, P. (1988) Cloning, characterization, and sequencing of an accessory gene regulator (agr) in Staphylococcus aureus. J Bacteriol 170: 4365-4372.
29. Perez-Casal, J., Caparon, M.G., and Scott, J.R. (1991) Mry, a trans-acting positive regulator of the M protein gene of Streptococcus pyogenes with similarity to the receptor proteins of two-component regulatory systems. J Bacteriol 173: 2617-2624.
30. Ranelli, D.M., Jones, C.L., Johns, M.B., Mussey, G.J., and Khan, S.A. (1985) Molecular cloning of staphylococcal enterotoxin B gene in Escherichia coli and Staphylococcus aureus. Proc Natl Acad Sci USA 82: 5850-5854.
31. Rosner, B.A. (1995) Regression and correlation methods. In Fundamentals of Biostatistics. Belmont, CA: Wadsworth Publishing Company, pp. 443-550.
32. Schäferkordt, S., and Chakraborty, T. (1995) Vector plasmid for insertional mutagenesis and directional cloning in Listeria spp. BioTechniques 19: 720-725.
33. Shryock, T.R., Dye, E.S., and Kapral, F.A. (1992) The accumulation of bactericidal lipids in staphylococcal abscesses. J Med Microbiol 36: 332-6.
34. Smeltzer, M.S., Gill, S.R., and Iandolo, J.J. (1992) Localization of a chromosomal mutation affecting expression of extracellular lipase in Staphylococcus aureus. J Bacteriol 174: 4000-4006.
35. Stark, W.M., Grindley, N.D.F., Hatfull, G.F., and Boocock, M.R. (1991) Resolvase-catalysed reactions between res sites differing in the central dinucleotide of subsite I. EMBO J 10: 3541-3548.
36. Sullam, P.M., Bayer, A.S., Foss, W.M., and Cheung, A.L. (1996) Diminished platelet binding in vitro by Staphylococcus aureus is associated with reduced virulence in a rabbit model of endocarditis. Infect Immun 64: 4915-4921.
37. Takiff, H.E., Baker, T., Copeland, T., Chen, S.-M., and Court, D.L. (1992) Locating essential Escherichia coli genes by using mini-Tn 10 transposons: pdxJ operon. J Bacteriol 174: 1544-1553.
38. Varón, D., Brody, M.S., and Price, C.W. (1996) Bacillus subtilis operon under the dual control of the general stress transcription factor sigma-B and the sporulation transcription factor sigma-H. Mol Microbiol 20: 339-350.
39. Wang, J., Mushegian, A., Lory, S., and Jin, S. (1996) Large-scale isolation of candidate virulence genes of Pseudomonas aeruginosa by in vivo selection. Proc Natl Acad Sci USA 93: 10434-10439.
40. Wirth, R., An, F., and Clewell, D.B. (1987) Highly efficient cloning system for Streptococcus faecalis: protoplast transformation, shuttle vectors, and applications. In Streptococcal Genetics. Ferretti, J.J., and Curtiss, III, R. (eds). Washington, DC: American Society for Microbiology Press, pp. 25-27.
41. Yanisch-Perron, C., Vieira, J., and Messing, J. (1985) Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33: 103-199.