Protective effect of the combined treatment of pancreatic and neutrophil elastase inhibitors on acute pancreatitis elicited by lipopolysaccharide in rats given intraductal injection of taurocholate plus trypsin

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 357, Issue 5, 1998, Pages 558-564

  Yamano, Mayumi ^a   Umeda, Masako ^a   Miyata, Keiji ^a   Yamada, Toshimitsu ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

Acute pancreatitis; Lipopolysaccharide (LPS); Multiple organ failure (MOF); Myeloperoxidase (MPO); Neutrophil elastase; Pancreatic elastase; Taurocholate; Trypsin

Indexed keywords

ENZYME INHIBITOR; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDE; TAUROCHOLIC ACID; TRYPSIN;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME INHIBITION; INTRAPERITONEAL DRUG ADMINISTRATION; MORTALITY; MULTIPLE ORGAN FAILURE; NONHUMAN; PANCREAS DUCT; PATHOGENESIS; PROPHYLAXIS; RAT;

ANIMALS; DRUG THERAPY, COMBINATION; ENZYME INHIBITORS; INJECTIONS, INTRAPERITONEAL; LEUKOCYTE ELASTASE; LIPOPOLYSACCHARIDES; MALE; PANCREATIC DUCTS; PANCREATIC ELASTASE; PEROXIDASE; RATS; RATS, WISTAR; TAUROCHOLIC ACID; TRYPSIN;

EID: 0031780237     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005208     Document Type: Article

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