Maintained vasodilatory response to cromakalim after inhibition of nitric oxide synthesis

Journal of Cardiovascular Pharmacology

Volumn 31, Issue 6, 1998, Pages 921-929

  Herrera, Gerald M ^a   Resta, Thomas C ^a   Candelaria, John J ^a   Walker, Benjimen R ^a  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

Author keywords

ATP sensitive K channel; Conscious rats; Endothelial cells; Endothelium dependent vasodilation; Intracellular calcium; Isolated rat lungs; Isolated rat tail arteries

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; ADENOSINE TRIPHOSPHATE; BRADYKININ; CALCIUM CHANNEL; CROMAKALIM; GLIBENCLAMIDE; IONOMYCIN; N(G) NITROARGININE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENDOTHELIUM CELL; HYPERPOLARIZATION; LUNG PERFUSION; MALE; NONHUMAN; PRESSOR RESPONSE; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE RELAXATION; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ANIMALS; ARTERIES; CALCIUM; CELLS, CULTURED; CROMAKALIM; ENDOTHELIUM, VASCULAR; MALE; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; TAIL; VASODILATOR AGENTS;

EID: 0031780133     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199806000-00017     Document Type: Article

References (40)

1. Nelson MT, Quayle JM. Physiological roles and properties of potassium channels in arterial smooth muscle. Am J Physiol 1995; 268:C799-822.
2. ATP channels in vascular smooth muscle. Cardiovasc Res 1994;28:797-804.
3. + channels. Trends Pharmacol Sci 1989;10:431-5.
4. + channels in arterial smooth muscle. Science 1989;245: 177-80.
5. 2+ and nitric oxide in bradykinin-stimulated vascular endothelial cells. Circ Res 1995;76: 922-4.
6. 2+ regulation and endothelial vascular function. Endothelium 1994;1:223-36.
7. Colden-Stanfield M, Schilling WP, Ritchie AK, Eskin SG, Navarro LT, Kunze DL. Bradykinin-induced increases in cytosolic calcium and ionic currents in cultured bovine aortic endothelial cells. Circ Res 1987;61:632-40.
8. Johns A, Lategan TW, Lodge NJ, Ryan US, Breemen CV, Adams DJ. Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells. Tissue Cell 1987;19:733-45.
9. Brunet PC, Bény JL. Substance P and bradykinin hyperpolarize pig coronary artery endothelial cells in primary culture. Blood Vessels 1989;26:228-34.
10. Busse R, Fichtner H, Lückhoff A, Kohlhardt M. Hyperpolarization and increased free calcium in acetylcholine-stimulated endothelial cells. Am J Physiol 1988;255:H965-9.
11. + channel in cultured bovine aortic endothelial cells. Pflugers Arch 1988;412: 469-81.
12. Lückhoff A, Busse R. Calcium influx into endothelial cells and formation of endothelium-derived relaxing factor is controlled by the membrane potential. Pflugers Arch 1990;416:305-11.
13. Lückhoff A, Busse R. Activators of potassium channels enhance calcium influx into endothelial cells as a consequence of potassium currents. Naunyn Schmiedebergs Arch Pharmacol 1990;342:94-9.
14. Katnik C, Adams DJ. An ATP-sensitive potassium conductance in rabbit arterial endothelial cells. J Physiol 1995;485:595-606.
15. + channels in rat aorta and brain microvascular endothelial cells. Am J Physiol 1993;265:C812-21.
16. + channels and nitric oxide on pial arterioles in piglets. J Cereb Blood Flow Metab 1996;16:1158-64.
17. + Channel pulmonary vasodilation in fetal lambs: role of endothelium-derived nitric oxide. J Appl Physiol 1992;73:188-94.
18. ω-nitro-L-arginine methyl ester-sensitive responses to cromakalim and diazoxide in the rat mesenteric bed. Eur J Pharmacol 1997; 319:229-38.
19. Brizzee BL, Russ RD, Walker BR. Role of vasopressin in acutely altered baroreflex sensitivity during hemorrhage in rats. Am J Physiol 1991;261:R677-85.
20. Eichinger MR, Resta TC, Balderrama DS, et al. Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia. J Appl Physiol 1995;79:1173-80.
21. Doyle MP, Galey WR, Walker BR. Reduced erythrocyte deformability alters pulmonary hemodynamics. J Appl Physiol 1989;67: 2593-9.
22. Russ RD, Walker BR. Maintained endothelium-dependent pulmonary vasodilation following chronic hypoxia in the rat. J Appl Physiol 1993;74:339-44.
23. Hakim TS. Identification of constriction in large versus small vessels using the arterial-venous and the double occlusion techniques in isolated canine lungs. Respiration 1988;54:61-9.
24. Townsley MI, Korthius RJ, Rippe B, Parker JC, Taylor AE. Validation of double occlusion method for Pc,i in lung and skeletal muscle. J Appl Physiol 1986;61:127-32.
25. McGuire PG, Orkin RW. A simple procedure to culture and passage endothelial cells from large vessels of small animals. Biol Techn 1987;5(6):546-54.
26. Guo J-P, Murohara T, Buerke M, Scalia R, Lefer AM. Direct measurement of nitric oxide release from vascular endothelial cells. J Appl Physiol 1996;81(2):774-9.
27. G-methylarginine, an inhibitor of endothelium-derived nitric oxide synthesis, is a potent pressor agent in the guinea pig: does nitric oxide regulate blood pressure in vivo? Biochem Biophys Res Commun 1989;160:881-6.
28. Elsner D, Müntze A, Kromer EP, Riegger GAJ. Inhibition of synthesis of endothelium derived nitric oxide in conscious dogs hemodynamic, renal, and hormonal effects. Am J Hypertens 1992;5: 288-91.
29. Rees DD, Palmer RMJ, Moncada S. Role of endothelium-derived nitric oxide in the regulation of blood pressure. Proc Natl Acad Sci U S A 1989;86:3375-8.
30. Hamilton TC, Weston AH. Cromakalim, nicorandil and pinacidil: novel drugs which open potassium channels in vascular smooth muscle. Gen Pharmacol 1989;20:1-9.
31. Kajioka S, Nakashima M, Kitamura K, Kuriyama H. Mechanisms of vasodilation induced by potassium-channel activators. Clin Sci 1991;81:129-39.
32. Beech DJ, Zhang H, Nakao K, Bolton TB. K Channel activation by nucleotide diphosphates and its inhibition by glibenclamide in vascular smooth muscle cells. Br J Pharmacol 1993;110:573-82.
33. Resta TC, Walker BR. Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation. Am J Physiol 1996;270:H888-96.
34. Katnik C, Adams DJ. Characterization of ATP-sensitive potassium channels in freshly dissociated rabbit aortic endothelial cells. Am J Physiol 1997;272:H2507-11.
35. Murphy HS, Maroughi M, Till GO, Ward PA. Phorbol-stimulated influx of extracellular calcium in rat pulmonary artery endothelial cells. Am J Physiol 1994;267:L145-51.
36. Randall MD, Griffith TM. Modulation of vasodilatation to levcromakalim by hypoxia and EDRF in the rabbit isolated ear: a comparison with pinacidil, sodium nitroprusside and verapamil. Br J Pharmacol 1993;109:386-93.
37. Taylor SG, Southerton JS, Weston AH, Baker JRJ. Endothelium-dependent effects of acetylcholine in rat aorta: a comparison with sodium nitroprusside and cromakalim. Br J Pharmacol 1988;94: 853-63.
38. Zhang H, Stockbridge N, Weir B, Vollrath B, Cook D. Vasodilation of canine cerebral arteries by nicorandil, pinacidil, and lemakalim. Gen Pharmacol 1992;23:197-201.
39. Okabe K, Kajioka S, Nakao K, Kitamura K, Kuriyama H, Weston AH. Actions of cromakalim on ionic currents recorded from single smooth muscle cells of the rat portal vein. J Pharmacol Exp Ther 1990;252:832-9.
40. + currents in rabbit sinus node and atrial myocytes. Biochim Biophys Acta 1995;1266:268-72.