Intelligent peptide-mapping method for recombinant human tissue-type plasminogen activator by lysyl-endopeptidase digestion

Analytica Chimica Acta

Volumn 365, Issue 1-3, 1998, Pages 241-247

  Shikata, Yasushi ^a   Kuwada, Manabu ^a   Hayashi, Yuichirou ^a   Hashimoto, Akira ^a   Koide, Atsushi ^a   Asakawa, Naoki ^a  

^a EISAI CO LTD   (Japan)

Author keywords

C4 column; HPLC; Lysyl endopeptidase; Peptide mapping; Sugar variant; Tissue type plasminogen activator (t PA)

Indexed keywords

PEPTIDE FRAGMENT; PROTEINASE; RECOMBINANT PLASMINOGEN ACTIVATOR;

AMINO ACID SEQUENCE; ARTICLE; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PEPTIDE MAPPING; PRIORITY JOURNAL; TECHNIQUE;

EID: 0031779425     PISSN: 00032670     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-2670(97)00603-X     Document Type: Article

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