Lecithin has no effect on serum lipoprotein, plasma fibrinogen and macro molecular protein complex levels in hyperlipidaemic men in a double-blind controlled study

European Journal of Clinical Nutrition

Volumn 52, Issue 6, 1998, Pages 419-424

  Oosthuizen, W ^a   Vorster, H H ^a   Vermaak, Wjh ^b   Smuts, C M ^c   Jerling, J C ^a   Veldman, F J ^a   Burger, H M ^a  

^a NORTH WEST UNIVERSITY   (South Africa)

^b UNIVERSITY OF PRETORIA   (South Africa)

^c Nutritional Intervention Res Unit   (South Africa)

Author keywords

Fibrinogen; Lecithin; Lipids; Lipoproteins; Macro molecular protein complex; Phospholipids

Indexed keywords

APOLIPOPROTEIN A; APOLIPOPROTEIN B; CHOLESTEROL; FIBRINOGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LINOLEIC ACID; LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PHOSPHATIDYLCHOLINE; PROTEIN; SUNFLOWER OIL; TRIACYLGLYCEROL; YOGHURT;

ADULT; ARTICLE; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLEX FORMATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FIBRINOGEN BLOOD LEVEL; HUMAN; HYPERLIPIDEMIA; LIPOPROTEIN BLOOD LEVEL; MALE; RANDOMIZED CONTROLLED TRIAL; SOYBEAN; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

GLYCINE MAX; HELIANTHUS;

EID: 0031779409     PISSN: 09543007     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejcn.1600580     Document Type: Article

References (27)

1. Beil FU & Grundy SM (1980): Studies on plasma lipoproteins during absorption of exogenous lecithin in man. J. Lipid. Res. 21, 525-536.
2. Childs MT, Bowlin JA, Ogilvie JT, Hazzard WR & Albers JJ (1981): The contrasting effects of a dietary soya lecithin product and corn oil on lipoprotein lipids in normolipidemic and familial hypercholesterolemic subjects. Atherosclerosis 38, 217-228.
3. Cobb M, Turkki P, Linscheer W & Raheja K (1980): Lecithin supplementation in healthy volunteers: effect on cholesterol esterification and plasma, and bile lipids. Nutr. Metab. 24, 228-237.
4. Conover WJ (1971): Practical Nonparametric Statistics. pp. 110-111. John Wiley & Sons Inc.: New York.
5. Davies LGG & Murdoch L (1959): "Lipostabil": A pilot study. Br. Med. J. 2, 619-620.
6. Ernst E & Resch KL (1993): Fibrinogen as a cardiovascular risk factor: a meta-analysis and review of the literature. Ann. Intern. Med. 118, 956-963.
7. Gouws E & Langenhoven ML (1986): Fatty Acid Composition. Amino Acid Composition. First Supplement to NRIND Food Composition Tables. 2nd edn, p. 80. Medical Research Council: Cape Town, South Africa.
8. Greten H, Raetzer H, Stiehl A & Schettler G (1980): The effect of polyunsaturated phosphatidylcholine on plasma lipids and fecal sterol excretion. Atherosclerosis 36, 81-88.
9. Gurr M (1993): Fats. In: Garrow JS & James WPT (eds) Human Nutrition & Dietetics. Churchill Livingstone: Edinburgh, pp. 77-101.
10. Kesaniemi YA & Grundy SM (1986): Effects of dietary polyenylphosphatidylcholine on metabolism of cholesterol and triglycerides in hypertriglyceridemic patients. Am. J. Clin. Nutr. 43, 98-107.
11. Knuiman JT, Beynen AC & Katan MB (1989): Lecithin intake and serum cholesterol. Am. J. Clin. Nutr. 49, 266-268.
12. Langenhoven ML, Kruger M, Gouws E & Faber M (1991): MRC Food Composition Tables. 3rd edn, p. 245. National Research Institute for Nutritional Disease of the South African Medical Research Council: Cape Town, South Africa.
13. Lands WEM (1995): Long-term fat intake and biomarkers. Am. J. Clin. Nutr. 61, 721S-725S.
14. Lee RD & Nieman DC (1993): Nutritional Assessment, p. 232. Madison: WCB Brown & Benchmark.
15. Lipinski B, Federman SM & Krolewski AS (1995): Macromolecular protein complex in human plasma: interaction with fibrin & fibrinolysis. Throm. Res. 78, 461-465.
16. Mahan LK & Arlin M (1992): Krause's Food, Nutrition and Diet Therapy, p. 49. W.B. Saunders Company: Philadelphia.
17. Morrison LM (1958): Serum cholesterol reduction with lecithin. Geriatrics 13, 12-19.
18. Newman B, Selby JV, Quesenberry CP Jr, King MC, Friedman GD & Fabsitz RR (1990): Nongenetic influences on obesity on other cardiovascular disease risk factors: an analysis of identical twins. Am. J. Public Health 80, 675-678.
19. Prack M, Sanborn T, Waugh D, Simkin H, Clark SB & Small DM (1983): Effects of polyunsaturated lecithin on plasma and lipoprotein cholesterol and fatty acids in normal men. In: Perkins EG & Visek WJ (eds) Dietary Fats and Health, American Oil Chemist's Society: USA, pp. 689-697.
20. Ratnoff OD & Menzies C (1951): A new method for the determination of fibrinogen in small samples of plasma J. Lab. Clin. Med. 37, 316-320.
21. Saba P, Galeone F, Salvadonni F, Pagliai E, Guidi G & Scalabrino A (1978): Effects of soyabean polyunsaturated phosphatidylcholine (Lipostabil®) on hyperlipoproteinemia. Curr. Ther. Res. 24, 299-306.
22. Simon JA, Hodgkins ML, Browner WS, Neuhaus JM, Bernert JT Jr & Hulley SB (1995): Serum fatty acids and the risk of coronary heart disease. Am. J. Epidemiol. 142, 469-476.
23. Smuts CM, Kruger M, Van Jaarsveld PJ, Fincham JE, Schall R, Van Der Merwe KJ & Benadé AJS (1992): The influence of fish oil supplementation on plasma lipoproteins and arterial lipids in Vervet monkeys with established atherosclerosis. Prostaglandins. Leukot. Essent. Fatty Acids 47, 129-138.
24. Steiner A & Domanski B (1944): Effect of feeding of soya lecithin on serum cholesterol level of man. Proc. Soc. Exp. Biol. Med. 55, 236-238.
25. Ter Welle HF, Van Gent CM, Dekker W & Willebrands AF (1974): The effect of soya lecithin on serum lipid values in type II hyperlipoproteinemia. Acta. Med. Scand. 195, 267-271.
26. Tompkins RK & Parkin LG (1980): Effects of long-term ingestion of soya phospholipids on serum lipids in humans. Am. J. Surg. 140, 360-364.
27. Veldman FJ (1996): Possible Mechanisms Through Which Pectin Influences Fibrinogen Concentration and Fibrin Network Structure. Unpublished thesis, pp. 1-219. Potchefstroom University for Christian Higher Education: Potchefstroom, South Africa.