Expression of the 150-kd oxygen-regulated protein in human breast cancer

Laboratory Investigation

Volumn 78, Issue 6, 1998, Pages 699-706

  Tsukamoto, Yoshitane ^a   Kuwabara, Keisuke ^b   Hirota, Seiichi ^b   Kawano, Kiyoshi ^c   Yoshikawa, Kiyoshi ^c   Ozawa, Kentaro ^b   Kobayashi, Tomohiro ^d   Yanagi, Hideki ^d   Stern, David M ^e   Tohyama, Masaya ^b   Kitamura, Yukihiko ^b   Ogawa, Satoshi ^b  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c OSAKA ROSAI HOSPITAL   (Japan)

^d Kyoto University   (Japan)

^e New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HEAT SHOCK PROTEIN; OXYGEN REGULATED PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER INVASION; CELL INFILTRATION; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REOXYGENATION; TISSUE SPECIFICITY;

ADENOCARCINOMA, MUCINOUS; ADULT; AGED; BLOTTING, NORTHERN; BLOTTING, WESTERN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEOPLASM INVASIVENESS; PROTEINS;

EID: 0031779303     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Cai JW, Henderson BW, Shen JW, and Subjeck JR (1993). Induction of glucose regulated proteins during growth of a murine tumor. J Cell Physiol 154:229-237.
2. Chen X, Easton D, Oh HJ, Lee-Yoon DS, Liu X, and Subjeck JR (1996). The 170 kDa glucose regulated stress protein is a large HSP70-, HSP110-like protein of the endoplasmic reticulum. FEBS Lett 380:68-72.
3. Chirgwin JM, Przybyla AE, MacDonald RJ, and Rutter WJ (1979). Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299.
4. Craven RA, Egerton M, and Stirling CJ (1996). A novel Hsp70 of the yeast ER lumen is required for the efficient translocation of a number of protein precursors. EMBO J 15:2640-2650.
5. Dierks T, Volkmer J, Schlenstedt G, Jung C, Sandholzer U, Zachmann K, Schlotterhose P, Neifer K, Schmidt B, and Zimmermann R (1996). A microsomal ATP-binding protein involved in efficient protein transport into mammalian endoplasmic reticulum. EMBO J 15:6931-6942.
6. Ebert BL, Firth JD, and Ratcliffe PJ (1995). Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct cis-acting sequences. J Biol Chem 270:29083-29089.
7. Ebert BL, Gleadle JM, O'Rourke JF, Bartlett SM, Poulton J, and Ratcliffe PJ (1996). Isoenzyme-specific regulation of genes involved in energy metabolism by hypoxia: Similarities with the regulation of erythropoietin. Biochem J 313:809-814.
8. Firth JD, Ebert BL, Pugh CW, and Ratcliffe PJ (1994). Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer. Proc Natl Acad Sci USA 91:6496-6500.
9. Firth JD, Ebert BL, and Ratcliffe PJ (1995). Hypoxic regulation of lactate dehydrogenase A: Interaction between hypoxia-inducible factor 1 and cAMP response elements. J Biol Chem 270:21021-21027.
10. Hirota S, Ito A, Nagoshi J, Takeda M, Kurata A, Takatsuka Y, Kohri K, Nomura S, and Kitamura Y (1995). Expression of bone matrix protein messenger ribonucleic acids in human breast cancers: Possible involvement of osteopontin in development of calcifying foci. Lab Invest 72:64-69.
11. Ikeda J, Kaneda S, Kuwabara K, Ogawa S, Kobayashi K, Matsumoto M, Yura T, and Yanagi H (1997). Cloning and expression of cDNA encoding the human 150 kDa oxygen-regulated protein. Biochem Biophys Res Commun 230:94-97.
12. Jamora C, Dennert G, and Lee AS (1996). Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. Proc Natl Acad Sci USA 93:7690-7694.
13. Kato S, Hirano A, Kato M, Herz F, and Ohama E (1993). Comparative study on the expression of stress-response protein (srp) 72, srp 27, B-crystallin and ubiquitin in brain tumors. An immunohistochemical investigation. Neuropathol Appl Neurobiol 19:436-442.
14. Koong AC, Chen EY, Lee AS, Brown JM, and Giaccia AJ (1994). Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction, Int J Radiat Oncol Biol Phys 28:661-666.
15. Kuwabara K, Matsumoto M, Ikeda J, Hori O, Ogawa S, Maeda Y, Kitagawa K, Imuta N, Kinoshita K, Stern DM, Yanagi H, and Kamada T (1996). Purification and characterization of a novel stress protein, the 150 kDa oxygen-regulated protein (ORP150), from cultured rat astrocytes and its expression in ischemic mouse brain. J Biol Chem 271: 5025-5032.
16. Kuznetsov G, Chen LB, and Nigam SK (1997). Multiple molecular chaperones complex with misfolded large oligomeric glycoproteins in the endoplasmic reticulum. J Biol Chem 272:3057-3063.
17. Li LJ, Li X, Ferrario A, Rucker N, Liu ES, Wong S, Corner CJ, and Lee AS (1992). Establishment of a Chinese hamster ovary cell line that expresses grp78 antisense transcripts and suppresses A23187 induction of both GRP78 and GRP94. J Cell Physiol 153:575-582.
18. Lin HY, Masso-Welch P, Di YP, Cai JW, Shen JW, and Subjeck JR (1993). The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin. Mol Biol Cell 4:1109-19.
19. Lowry O, Rosenbrough NJ, Farr LA, and Randall RJ (1951). Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275.
20. Maines MD and Abrahamsson P (1996). Expression of heme oxygenase-1 (HSP32) in human prostate: Normal, hyperplastic, and tumor tissue distribution. Urology 47:727-733.
21. Murphy BJ, Laderoute KR, Short SM, and Sutherland RM (1991). The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells. Br J Cancer 64:69-73.
22. 2+ - binding protein with a carboxy-terminal NDEL sequence showed partial homology with 70-kDa heat shock protein (hsp70). Cell Struct Funct 20:133-141.
23. Oesterreich S, Weng CN, Qiu M, Hilsenbeck SG, Osborne CK, and Fuqua SA (1993). The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines. Cancer Res 53:4443-4448.
24. Ratcliffe PJ, Ebert BL, Firth DJ, Gleadle JM, Maxwell PH, Nagao M, O'Rourke JF, Pugh CW, and Wood SM (1997). Oxygen regulated gene expression: Erythropoietin as a model system. Kidney Int 51:514-526.
25. Sanger A, Nicklen S, and Coulson A (1977). DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467.
26. Sciandra JJ, Subjeck JR, Hughes CS (1984). Induction of glucose-regulated proteins during anaerobic exposure and of heat-shock proteins after reoxygenation. Proc Natl Acad Sci USA 81:4843-4847.
27. Semenza GL (1996). Transcriptional regulation by hypoxia-inducible factor 1: Molecular mechanisms of oxygen homeostasis. Trends Cardiovasc Med 6:151-158.
28. Semenza GL, Roth PH, Fang HM, and Wang GL (1994). Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1. J Biol Chem 269: 23757-23763.
29. Shen J, Hughes C, Chao C, Cai J, Bartels C, Gessner T, and Subjeck JR (1987). Coinduction of glucose regulated proteins and doxorubicin resistance in Chinese hamster cells. Proc Natl Acad Sci USA 84:3278-3282.
30. Shiu RPC, Pouyssegur J, and Pastan I (1977). Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous sarcoma virus-transformed chick embryo fibroblasts. Proc Natl Acad Sci USA 74:3840-3844.
31. Thor A, Benz C, Moore D II, Goldman E, Edgerton S, Landry J, Schwartz L, Mayall B, Hickey E, and Weber LA (1991). Stress response protein (srp-27) determination in primary human breast carcinoma: Clinical, histological, and prognostic correlations. J Natl Cancer Inst 83:170-178.
32. Tsukamoto Y, Kuwabara K, Hirota S, Ikeda J, Stern D, Yanagi H, Matsumoto M, Ogawa S, and Kitamura Y (1996). 150-kD oxygen-regulated protein is expressed in human atherosclerotic plaques and allows mononuclear phagocytes to withstand cellular stress on exposure to hypoxia and modified low density lipoprotein. J Clin Invest 98:1930-1941.
33. Vaupel P, Kallinowski F, and Okunieff P (1989). Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review. Cancer Res 49:6449-6465.