The effects of extracellular pH with and without bicarbonate on intracellular procaine concentrations and anesthetic effects in crayfish giant axons

Anesthesiology

Volumn 88, Issue 6, 1998, Pages 1549-1557

  Ibusuki, Shoichiro ^a   Katsuki, Hiroshi ^b   Takasaki, Mayumi ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b NONE

Author keywords

Crayfish; Ion selective electrodes; Local anesthetics; Microelectrodes; Procaine; Sodium bicarbonate

Indexed keywords

BICARBONATE; LOCAL ANESTHETIC AGENT; PROCAINE;

ACIDIFICATION; ALKALINIZATION; ANESTHESIA MECHANISM; ANIMAL CELL; ARTICLE; CELL PH; CONTROLLED STUDY; CRAYFISH; EVOKED RESPONSE; GIANT AXON; IONIZATION; LOCAL ANESTHESIA; MICROELECTRODE; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL;

ACTION POTENTIALS; ANESTHETICS, LOCAL; ANIMALS; ASTACOIDEA; AXONS; DRUG SYNERGISM; HYDROGEN-ION CONCENTRATION; MICROELECTRODES; PROCAINE; SODIUM BICARBONATE;

EID: 0031779230     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199806000-00019     Document Type: Article

References (31)

1. Catchlove RFH: Potentiation of two different local anaesthetics by carbon dioxide. Br J Anaesth 1973; 45:471-4
2. 2. Anesth Analg 1987; 66:9-17
3. Tetzlaff JE, Yoon HJ, Brems J, Javorsky T: Alkalinization of mepivacaine improves the quality of motor block associated with interscalene brachial plexus anesthesia for shoulder surgery. Reg Anesth 1995; 20:128-32
4. Benzon HT, Toleikis JR, Dixit P, Goodman I, Hill JA: Onset, intensity of blockade and somatosensory evoked potential changes of the lumbosacral dermatomes after epidural anesthesia with alkalinized lidocaine. Anesth Analg 1993; 76:328-32
5. DiFazio CA, Carron H, Grosslight KR, Moscicki JC, Bolding WR, Johns RA: Comparison of pH-adjusted lidocaine solutions for epidural anesthesia. Anesth Analg 1986; 65:760-4
6. Capogna G, Celleno D, Laudano D, Giunta F: Alkalinization of local anesthetics. Which block, which local anesthetic? Reg Anesth 1995; 20:369-77
7. Narahashi T, Frazier DT, Yamada M: The site of action and active form of local anesthetics. I. Theory and pH experiments with tertiary compounds. J Pharmacol Exp Ther 1970; 171:32-51
8. Ritter JM, Doktor HS, Benjamin N: Paradoxical effect of bicarbonate on cytoplasmic pH. Lancet 1990; 335:1243-6
9. 2 and pH on local anesthetic action. J Pharmacol Exp Ther 1972; 181:298-309
10. Wallin BG: Intracellular ion concentration in single crayfish axons. Acta Physiol Scand 1967; 70:419-30
11. Ammann D, Lanter F, Steiner RA, Schulthess P, Shijo Y, Simon W: Neutral carrier based hydrogen ion selective microelectrode for extra- and intracellular studies. Anal Chem 1981; 53:2267-9
12. Kubota T, Hagiwara N, Fujimoto M: Intracellular calcium measurements with PVC-resin Ca-selective microelectrodes in frog proximal tubules and sartorius muscle fibers. Jpn J Physiol 1990; 40:79-95
13. Yokono A, Satake H, Kaneshina S, Yokono S, Ogli K: Local anesthetic-sensitive electrodes: Preparation of coated-wire electrodes and their basic properties in vitro. Anesth Analg 1992; 75:1063-9
14. Satake H, Hori H, Kaneshina S: A coated wire electrode sensitive to tetraphenylphosphonium ion for measurement of the mitochondrial membrane potential. Anal Lett 1991; 24:295-304
15. Bouklouze AA, El-Jammal A, Patriarche GJ, Christian GD: New modified polymeric electrodes selective to local anaesthetic compounds. J Pharm Biomed Anal 1991; 9:393-9
16. Shoukry AF, Issa YM, El-Sheik R, Zareh M: Plastic membrane ion selective electrodes for the determination of some anesthetic compounds. Microchem J 1988; 37:299-305
17. Butterworth JF IV, Strichartz GR: Molecular mechanisms of local anesthesia: A review. ANESTHESIOLOGY 1990; 72:711-34
18. 2+-selective electrodes: A novel PVC-gelled neutral carrier mixture compared with other currently available sensors. J Neurosci Meth 1981; 4:73-86
19. Lee CO, Im WB, Sonn JK: Intracellular sodium ion activity: Reliable measurement and stimulation-induced change in cardiac Purkinje fibers. Can J Physiol Pharmacol 1987; 65:954-62
20. Guilbault GG, Durst RA, Frant MS, Freiser H, Hansen EH, Light TS, Pungor E, Rechnitz G, Rice NM, Rohm TJ, Simon W, Thomas JDR: Recommendations for nomenclature of ion-selective electrodes. Pure Appl Chem 1976; 48:129-32
21. Roos A, Boron WF: Intracellular pH. Physiol Reviews 1981; 61:296-434
22. 14-procaine and lidocaine in intact and desheathed sciatic nerve trunks. J Pharmacol Exp Ther 1970; 172:18-32
23. Bianchi CP, Bolton TC: Action of local anesthetics on coupling systems in muscle. J Pharmacol Exp Ther 1967; 157:388-405
24. 14C in single giant axons of the squid. Neuropharmacology 1972; 11:727-32
25. Ritchie JM, Ritchie B, Greengard P: The effect of the nerve sheath on the action of local anesthetics. J Pharmacol Exp Ther 1965; 150:160-4
26. Bromage PR, Burfoot MF, Crowell DE, Truant AP: Quality of epidural blockade III: Carbonated local anaesthetic solutions. Br J Anaesth 1967; 39:197-209
27. Schwarz W, Palade PT, Hille B: Local anesthetics: Effect of pH on use-dependent block of sodium channel in frog muscle. Biophys J 1977; 20:343-68
28. + buffering power of snail neurones. J Physiol 1989; 409:89-101
29. Wong K, Strichartz GR, Raymond SA: On the mechanisms of potentiation of local anesthetics by bicarbonate buffer: Drug structure-activity studies on isolated peripheral nerve. Anesth Analg 1993; 76:131-43
30. 2 at constant pH. Reg Anesth 1990; 15:89-93
31. Hille B: Local anesthetics: Hydrophilic and hydrophobic pathways for the drug receptor reactions. J Gen Physiol 1977; 69:497-515