Synthesis of (S)-1-(1H-indol-4-yloxy)-3[4-(3-methoxyphenyl)-4- hydroxypiperidin-1-yl]-propan-2-ol (LY333068) succinate, and its 3-[14C]- isotopomer based on chiral glycerol-[14C] derivatives

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 41, Issue 6, 1998, Pages 465-475

  Czeskis, Boris A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

5HT(1A) antagonist; Carbon 14 labeled; LY333068 succinate

Indexed keywords

AMINO ACIDS; CARBOXYLATION; ISOMERS; ISOTOPES;

5HT(1A) ANTAGONIST; BUILDING BLOCKES; CARBON 14; CARBON 14 LABELED; DIOXOLANE; HYDROXYINDOLES; ISOTOPOMERS; L-SERINE; LY333068 SUCCINATE; RADIOCHEMICAL YIELD;

CARBON;

1 (1H INDOL 4 YLOXY) 3 [4 (3 METHOXYPHENYL) 4 HYDROXYPIPERIDIN 1 YL] PROPAN 2 OL SUCCINATE; 1,3 DIOXOLANE DERIVATIVE; 2,2 DIMETHYL 1,3 DIOXOLANE 4 CARBOXYLATE; GLYCEROL; LY 333068; SERINE; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; CHIRALITY; DEAMINATION; DRUG SYNTHESIS; ESTERIFICATION; ISOTOPE LABELING; RADIOCHEMISTRY; STRUCTURE ANALYSIS;

EID: 0031779201     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199806)41:6<465::AID-JLCR103>3.0.CO;2-B     Document Type: Article

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