DNA as a basis for acquired long-term memory in neurons

Medical Hypotheses

Volumn 50, Issue 5, 1998, Pages 451-455

  Bergin, R ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DNA DETERMINATION; DNA SEQUENCE; HUMAN; HYPOTHESIS; LONG TERM MEMORY; LONG TERM POTENTIATION; NERVE CELL; PRIORITY JOURNAL;

EID: 0031779156     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(98)90218-3     Document Type: Article

References (57)

1. Magner L N. A History of Medicine. New York: Marcel Dekker, 1992.
2. Descartes R. Treatise on man. In: The Philosophical Writings of Descartes. Cambridge: Cambridge University Press, 1985.
3. Ebbinghaus H. Über das Gedachtnis. Leipzig: Duncker, 1885.
4. Ferrier D. The Functions of the Brain. London: Smith, Elder, & Co, 1886.
5. Jackson J H. The Croonian lectures on evolution and dissolution of the nervous system. Br Med J 1884; 1: 591-593.
6. James W. The Principles of Psychology. New York: Henry Holt & Co, 1890.
7. Korsakoff S S. Étude médico-psychologique sur une forme des maladies de la mémoire. Revue Philosophique 1889; 5: 501-530.
8. Ribot T H. The Diseases of Memory. New York: Appleton & Co, 1882.
9. Eccles J C. The Neurophysiological Basis of Mind. Oxford: Clarendon Press, 1953.
10. Hebb D O. The Organization of Behaviour. New York: Wiley, 1949.
11. Martinez J L Jr, Derrick BE. Long-term potentiation and learning. Annu Rev Psychol 1996; 47: 173-203.
12. Gallistel R. Is long-term potentiation a plausible basis for memory? In: McGaugh J L, Weinberger N M, Lynch G, eds. Brain and Memory: Modulation and Mediation of Plasticity. New York: Oxford University Press, 1995: 328-337.
13. Rochester N, Holland J H, Haibt L H, Duda W L. Tests on a cell assembly theory of the action of the brain, using a large digital computer. IRE Trans Inform Theory 1956; IT-2: 80-93.
14. MacGregor R J, McMullen T. Computer simulations of diffusely connected neuronal populations. Biol Cybern 1978; 28: 12-127.
15. Lansner A, Fransen E. Modeling Hebbian cell assemblies comprised of cortical neurons. Network 1992; 3: 105-119.
16. Lashley K S. In search of the engram. Symp Soc Exp Biol 1950; 4: 454-482.
17. Byrne W L, Samuel D, Bennet E L et al. Memory transfer. Science 1966; 153: 658-659.
18. Ungar G. Molecular mechanisms in information processing. Int Rev Neurobiol 1970; 13: 223-250.
19. Dudai Y. The Neurobiology of Memory: Concepts, Findings, Trends. Oxford: Oxford University Press, 1989.
20. Dingman W, Sporn M B. The incorporation of 8-azaguanine into rat brain RNA and its effects on maze learning by the rat: an inquiry into the chemical basis of memory. J Psychiatr Res 1961; 1: 1-11.
21. Flexner J B, Flexner L B, Stellar E. Memory in mice as affected by intracerebral puromycin. Science 1963; 141: 567-569.
22. Barondes S H. Protein-synthesis dependent and protein-synthesis independent memory storage processes. In: Deutsch D, Deutsch J A, eds Short-term Memory. New York: Academic Press, 1975: 379-390.
23. Hydén H. The differentiation of brain cell protein, learning and memory. BioSystems 1977; 8: 213-218.
24. Kandel E R. Genes, nerve cells, and the remembrance of things past. J Neuropsychiatry Clin Neurosci 1989; 1: 103-125.
25. Spatz H C. Posttranslational modification of protein kinase A: the link between short-term and long-term memory. Behav Brain Res 1995; 66: 79-84.
26. Frank D A, Greenberg M E. CREB: A mediator of long-term memory from mollusks to mammals. Cell 1994; 79: 5-8.
27. Yin J C P, Wallach J S, Del Vecchio M et al. Induction of a dominant negative CREB transgene-specifically blocks long-term memory in Drosophila. Cell 1994; 79: 49-58.
28. Mayford M, Abel T, Kandel E R. Transgenic approaches to cognition. Curr Opin Neurobiol 1995; 5: 141-148.
29. Malinow R, Schulman H, Tsien R W. Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP. Science 1989; 245: 862-866.
30. O'Dell T J, Kandel E R, Grant SGN. Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors. Nature 1991; 353: 558-560.
31. Silva A J, Stevens C F, Tonegawa S, Wang Y. Deficient hippocampal long-term potentation in α-calcium-calmodulin kinase II mutant mice. Science 1992; 257: 201-206.
32. Silva A J, Paylor R, Wehner J M, Tonegawa S. Impaired spatial learning in α-calcium-calmodulin kinase II mutant mice. Science 1992; 257: 206-211.
33. DeZazzo J, Tully T. Dissection of memory formation: from behavioral pharmacology to molecular genetics. Trends Neurosci 1995; 18: 212-218.
34. Giuditta A, Libonati M, Packard A, Prozzo N. Nuclear counts in the brain lobes of Octopus Vulgaris as a function of body size. Brain Res 1971; 25: 55-62.
35. De Marianis B, Olmo E, Giuditta A. Excess DNA in the nuclei of the subesophageal region of octopus brain. J Comp Neurol 1979; 186: 293-300.
36. Stambolova M A, Cox D, Mathias A P. The occurrence of two types of deoxyribonucleic acid polymerase activity in the main classes of nuclei obtained from the brains of infant and adult rats. Biochem J 1974; 140: 65-71.
37. Kimberlin R H, Shirt D B, Collis S C. The turnover of isotopically labelled DNA in vivo in developing, adult and scrapie-affected mouse brain. J Neurochem 1974; 23: 241-248.
38. Perrone-Capano C, D'Onofrio G, Giuditta A. DNA turnover in rat cerebral cortex. J Neurochem 1982; 38: 52-56.
39. 3H-thymidine incorporation into brain DNA during learning. Physiol Chem Phys 1972; 4: 391-397.
40. 3H-thymidine during learning. Physiol Chem Phys 1972; 4: 335-338.
41. Giuditta A, Perrone-Capano C, D'Onofrio G, Toniatti C, Menna T, Hydén H. Synthesis of rat brain DNA during acquisition of an appetitive task. Pharmacol Biochem Behav 1986; 25: 651-658.
42. Giuditta A, Abrescia P, Rutigliano B. Effect of electroshock on thymidine incorporation into rat brain DNA. J Neurochem 1978; 31: 983-987.
43. von Neumann J. The Computer and the Brain. New Haven, CT: Yale University Press, 1958: 63-64.
44. Lindahl T, Nyberg B. Rate of depurination of native deoxyribonucleic acid. Biochemistry 1972; 11: 3610-3618.
45. Walker A P, Bachelard H S. Studies on DNA damage and repair in the mammalian brain. J Neurochem 1988; 51: 1394-1399.
46. Hanawalt P C, Gee P, Ho L, Hsu R K, Kane C J M. Genomic heterogeneity of DNA repair: role in aging? Ann NY Acad Sci 1992; 663: 17-25.
47. Vilenchik M M, Tretjak T M. Evidence for unscheduled DNA synthesis in rat brain. J Neurochem 1977; 29: 1159-1161.
48. Ishikawa T, Takayama S, Kitagawa T. Autoradiographic demonstration of DNA repair synthesis in ganglion cells of aquarium fish at various age in vivo. Virchows Arch B Cell Pathol 1978; 28: 235-242.
49. Wintzerith M, Wittendorp E, Rechenmann R V, Mandel P. Nuclear, nucleolar-repair, or turnover of DNA in adult rat brain. J Neurosci Res 1977; 3(3): 217-230.
50. Subrahmanyam K, Subba Rao K. Ultraviolet light-induced unscheduled DNA-synthesis in isolated neurons of rat brain of different ages. Mech Ageing Dev 1991; 57: 283-291.
51. Heyting C, van't Veer L. Repair of ethymitrosurea-induced DNA damage in the newborn rat, II: Localization of unscheduled DNA synthesis in the developing rat brain. Carcinogenesis 1981; 2: 1173-1180.
52. 3H-thymidine. Curr Mod Biol 1968; 2: 274-282.
53. Moroz P E. A hypothesis of the code of nerve impulses. Acta Biotheor 1980; 29 101-109.
54. Lipton R J. DNA solution of hard computational problems. Science 1995; 268: 542-545.
55. Adleman L M. Molecular computation of solutions to combinatorial problems. Science 1994; 266: 1021-1024.
56. Berg R H, Hvilstedt S, Ramanujam P S. Peptide oligomers for holographic data storage. Nature 1996; 383: 505-508.
57. Bergin R, Giesecke J, Fagerholm P. Unpublished results, 1981.