Human antithrombin III variant production from recombinant BHK cells in a fed-batch culture with on-line control of glucose and glutamine concentrations

Journal of Fermentation and Bioengineering

Volumn 85, Issue 5, 1998, Pages 532-535

  Honda, Hiroyuki ^a   Lenas, Petros ^a   Watanabe, Hideki ^b   Kitade, Tamotsu ^a   Kobayashi, Takeshi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b EISAI CO LTD   (Japan)

Author keywords

Antithrombin III; BHK cells; Fed batch culture; Mammalian cell culture; Monosaccharide content

Indexed keywords

ANIMAL CELL CULTURE; BATCH CELL CULTURE; DRUG PRODUCTS; GLUCOSE; PROTEINS;

FED-BATCH CULTURE; HUMAN ANTITHROMBIN;

GENETIC ENGINEERING;

ANTITHROMBIN III; GLUCOSE; GLUTAMINE;

ANIMAL CELL; ARTICLE; CELL METABOLISM; CELL STRAIN BHK; CULTURE MEDIUM; NONHUMAN; PROTEIN SYNTHESIS;

ANIMALIA; MAMMALIA;

EID: 0031778742     PISSN: 0922338X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0922-338X(98)80102-5     Document Type: Article

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