The plasma FK506-binding protein 12 level is related to acute cellular rejection in small bowel transplantation

Immunopharmacology and Immunotoxicology

Volumn 20, Issue 2, 1998, Pages 211-216

  Tarumi, K ^a   Yagihashi, A ^a   Watanabe, N ^a   Kameshima, H ^a   Yajima, T ^a   Hirata, K ^a  

^a SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ACR; FK506; FKBP12; SBTx

Indexed keywords

BINDING PROTEIN; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 4; TACROLIMUS; TUMOR NECROSIS FACTOR ALPHA;

ALLOGRAFT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFICACY; ENZYME ACTIVITY; GRAFT REJECTION; IMMUNOSUPPRESSIVE TREATMENT; INTESTINE TRANSPLANTATION; ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

EID: 0031778730     PISSN: 08923973     EISSN: None     Source Type: Journal    
DOI: 10.3109/08923979809038540     Document Type: Article

References (10)

1. Todo S, Tzakis A, Ryes J, et al. Small intestinal transplantation in humans with or without the colon. Transplantation 27:840-848, 1994.
2. Fruman DA, Burakoff SJ, Bierer BE. Immunophilins in protein folding and immunosuppression. FASEB J 8:391-400, 1994.
3. Shirakata Y, Kobayashi M, Ohtsuka K, et al. Inhibitory effect of plasma FKBP12 on immunosuppressive activity of FK506. Transplantation 27:1582-1587, 1995.
4. Monchik GJ, Russell PS. Transplantation of small bowel in the rat: technical and immunological consideration. Surgery 70:693-702, 1971.
5. Grenier FC, Luczkiw J, Bergmann M, et al. A whole blood FK506 assay for the IMx analyzer. Transplant Proc 23:2748-2749, 1991.
6. Kobayashi M, Ohtsuka K, Tamura K, et al. Production of monoclonal antibody against recombinant human FKBP-12 and subcellular localization of FKBP-12 in human mononuclear and polymorphonuclear cells. Transplant Proc 25:655-657, 1993.
7. Sherry B, Yarlett N, Strupp A, Cerami A. Identification of cyclophilin as a proinflammatory secretory product of lipopolysaccharide-activated macrophages. Proc Natl Acad Sci USA 89:3511-3515, 1992.
8. Xu Q, Leiva MC, Fischkoff SA, Handschumacher RE, Lyttle CR. Leukocyte chemotactic activity of cyclophilin. J Biol Chem 267:11968-11971, 1992.
9. Leiva MC, Lyttle CR. Leukocyte chemotactic activity of FKBP and inhibition by FK506. Biochem Biophys Res Commun 186:1178-1183, 1992
10. Todo S, Fung JJ, Starzl TE, et al. Liver, kidney and thoracic organ transplantation under FK506. Ann Surg 22:13, 1990.